نتائج البحث

An RNA-targeting CRISPR–Cas13d system alleviates disease-related phenotypes in Huntington’s disease models

• Authors : Morelli, Kathryn H; Wu, Qian; Gosztyla, Maya L

Subjects: Medical Biotechnology; Biomedical and Clinical Sciences; Neurosciences

• Source: Nature Neuroscience. 26(1)

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Profiling the mouse brain endothelial transcriptome in health and disease models reveals a core blood–brain barrier dysfunction module

• Authors : Munji, Roeben Nocon; Soung, Allison Luen; Weiner, Geoffrey Aaron

Subjects: Biomedical and Clinical Sciences; Neurosciences; Human Genome

• Source: Nature Neuroscience. 22(11)

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Oligodendrocytes produce amyloid-β and contribute to plaque formation alongside neurons in Alzheimer's disease model mice.

• Authors : Sasmita AO; Department of Neurogenetics, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany. .; International Max Planck Research School for Neurosciences, Göttingen, Germany. .

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/metabolism ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/pathology ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/genetics

• Source: Nature neuroscience [Nat Neurosci] 2024 Sep; Vol. 27 (9), pp. 1668-1674. Date of Electronic Publication: 2024 Aug 05.Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 9809671 Publication Model: Print-Electronic Cited Medium: Internet

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Rescue of long-range circuit dysfunction in Alzheimer's disease models.

• Authors : Busche MA; Institute of Neuroscience, Technische Universität München, Munich, Germany.; Department of Psychiatry and Psychotherapy, Technische Universität München, Munich, Germany.

Subjects: Alzheimer Disease/Alzheimer Disease/Alzheimer Disease/*pathology ; Amyloid beta-Peptides/Amyloid beta-Peptides/Amyloid beta-Peptides/*metabolism ; Hippocampus/Hippocampus/Hippocampus/*physiopathology

• Source: Nature neuroscience [Nat Neurosci] 2015 Nov; Vol. 18 (11), pp. 1623-30. Date of Electronic Publication: 2015 Oct 12.Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 9809671 Publication Model: Print-Electronic Cited Medium: Internet

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Opportunities and challenges of pluripotent stem cell neurodegenerative disease models.

• Authors : Sandoe, Jackson¹; Eggan, Kevin²

• Source: Nature Neuroscience. Jul2013, Vol. 16 Issue 7, p780-789. 10p.

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Selective elimination of glutamatergic synapses on striatopallidal neurons in Parkinson disease models.

• Authors : Day, Michelle¹; Zhongfeng Wang¹; Jun Ding¹

• Source: Nature Neuroscience. Feb2006, Vol. 9 Issue 2, p251-259. 9p. 1 Black and White Photograph, 4 Graphs.

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Rescue of long-range circuit dysfunction in Alzheimer's disease models

• Authors : Marc Aurel Busche; Maja Kekuš; Hans Förstl

Subjects: Neocortex; Amyloid beta-Peptides; Mechanism (biology)

• Source: Nature neuroscience. 18(11)

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Neutrophil adhesion in brain capillaries reduces cortical blood flow and impairs memory function in Alzheimer's disease mouse models.

• Authors : Cruz Hernández, Jean C; Bracko, Oliver; Kersbergen, Calvin J

Subjects: Capillaries; Brain; Neutrophils

• Source: Nature neuroscience. 22(3)

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Dysfunction of cortical GABAergic neurons leads to sensory hyper-reactivity in a Shank3 mouse model of ASD

• Authors : Chen, Qian; Deister, Christopher A; Gao, Xian

Subjects: Mental Health; Intellectual and Developmental Disabilities (IDD); Autism

• Source: Nature Neuroscience. 23(4)

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Impaired perceptual learning in a mouse model of Fragile X syndrome is mediated by parvalbumin neuron dysfunction and is reversible.

• Authors : Goel, Anubhuti; Cantu, Daniel A; Guilfoyle, Janna

Subjects: Visual Cortex; Neuropil; Neurons

• Source: Nature neuroscience. 21(10)

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