نتائج البحث

Abundant clock proteins point to missing molecular regulation in the plant circadian clock.

• Authors : Urquiza-García, Uriel^1,2,3 (AUTHOR); Molina, Nacho^1,4 (AUTHOR); Halliday, Karen J⁵ (AUTHOR)

• Source: Molecular Systems Biology. Apr2025, Vol. 21 Issue 4, p361-389. 29p.

تفاصيل العنوان

Gemcitabine and ATR inhibitors synergize to kill PDAC cells by blocking DNA damage response.

• Authors : Höfer S; Chair of Proteomics and Bioanalytics, Technical University of Munich, Freising, Germany.; Frasch L

Subjects: Deoxycytidine*/Deoxycytidine*/Deoxycytidine*/analogs & derivatives ; Deoxycytidine*/Deoxycytidine*/Deoxycytidine*/pharmacology ; DNA Damage*/DNA Damage*/DNA Damage*/drug effects

• Source: Molecular systems biology [Mol Syst Biol] 2025 Mar; Vol. 21 (3), pp. 231-253. Date of Electronic Publication: 2025 Jan 21.Publisher: EMBO Press Country of Publication: Germany NLM ID: 101235389 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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High‐throughput metabolomics predicts drug–target relationships for eukaryotic proteins.

• Authors : Holbrook‐Smith, Duncan¹ (AUTHOR); Durot, Stephan¹ (AUTHOR); Sauer, Uwe¹ (AUTHOR)

• Source: Molecular Systems Biology. Feb2022, Vol. 18 Issue 2, p1-16. 16p.

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Systematic identification of 20S proteasome substrates.

• Authors : Pepelnjak, Monika¹ (AUTHOR); Rogawski, Rivkah² (AUTHOR); Arkind, Galina² (AUTHOR)

• Source: Molecular Systems Biology. Apr2024, Vol. 20 Issue 4, p403-427. 25p.

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Systematic discovery of protein interaction interfaces using AlphaFold and experimental validation.

• Authors : Lee CY; Institute of Molecular Biology (IMB) gGmbH, 55128, Mainz, Germany.; Hubrich D

Subjects: Proteins*/Proteins*/Proteins*/metabolism ; Carrier Proteins*; Humans

• Source: Molecular systems biology [Mol Syst Biol] 2024 Feb; Vol. 20 (2), pp. 75-97. Date of Electronic Publication: 2024 Jan 15.Publisher: EMBO Press Country of Publication: Germany NLM ID: 101235389 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Global atlas of predicted functional domains in Legionella pneumophila Dot/Icm translocated effectors.

• Authors : Patel DT; Department of Microbiology, Immunology and Infectious Diseases, University of Calgary, Calgary, AB, T2N 4N1, Canada.; Stogios PJ

Subjects: Legionella pneumophila*/Legionella pneumophila*/Legionella pneumophila*/metabolism ; Legionella pneumophila*/Legionella pneumophila*/Legionella pneumophila*/genetics ; Bacterial Proteins*/Bacterial Proteins*/Bacterial Proteins*/metabolism

• Source: Molecular systems biology [Mol Syst Biol] 2025 Jan; Vol. 21 (1), pp. 59-89. Date of Electronic Publication: 2024 Nov 19.Publisher: EMBO Press Country of Publication: Germany NLM ID: 101235389 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Deep quantification of substrate turnover defines protease subsite cooperativity.

• Authors : Gudipati RK; Friedrich Miescher Institute for Biomedical Research, Fabrikstrasse 24, Basel, 4056, Switzerland.; Center for Advanced Technologies, Adam Mickiewicz University, Uniwersytetu Poznańskiego 10, 61-614, Poznań, Poland.

Subjects: Dipeptidyl Peptidase 4*/Dipeptidyl Peptidase 4*/Dipeptidyl Peptidase 4*/metabolism ; Dipeptidyl Peptidase 4*/Dipeptidyl Peptidase 4*/Dipeptidyl Peptidase 4*/chemistry ; Caenorhabditis elegans*/Caenorhabditis elegans*/Caenorhabditis elegans*/enzymology

• Source: Molecular systems biology [Mol Syst Biol] 2024 Dec; Vol. 20 (12), pp. 1303-1328. Date of Electronic Publication: 2024 Oct 28.Publisher: EMBO Press Country of Publication: Germany NLM ID: 101235389 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Systematic identification of structure-specific protein–protein interactions.

• Authors : Holfeld, Aleš¹ (AUTHOR); Schuster, Dina^1,2,3 (AUTHOR); Sesterhenn, Fabian¹ (AUTHOR)

• Source: Molecular Systems Biology. Jun2024, Vol. 20 Issue 6, p651-675. 25p.

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Phosphorylation-linked complex profiling identifies assemblies required for Hippo signal integration.

• Authors : Uliana F; Department of Biology, Institute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland.; Department of Biology, Institute of Biochemistry, ETH Zurich, Zurich, Switzerland.

Subjects: Signal Transduction* ; Adaptor Proteins, Signal Transducing*/Adaptor Proteins, Signal Transducing*/Adaptor Proteins, Signal Transducing*/metabolism; Humans

• Source: Molecular systems biology [Mol Syst Biol] 2023 Apr 12; Vol. 19 (4), pp. e11024. Date of Electronic Publication: 2023 Mar 10.Publisher: EMBO Press Country of Publication: Germany NLM ID: 101235389 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Identification of type VI secretion system effector-immunity pairs using structural bioinformatics.

• Authors : Geller AM; Department of Plant Pathology and Microbiology, The Institute of Environmental Science, The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot, Israel.; Shalom M

Subjects: Computational Biology*/Computational Biology*/Computational Biology*/methods ; Type VI Secretion Systems*/Type VI Secretion Systems*/Type VI Secretion Systems*/genetics ; Type VI Secretion Systems*/Type VI Secretion Systems*/Type VI Secretion Systems*/metabolism

• Source: Molecular systems biology [Mol Syst Biol] 2024 Jun; Vol. 20 (6), pp. 702-718. Date of Electronic Publication: 2024 Apr 24.Publisher: EMBO Press Country of Publication: Germany NLM ID: 101235389 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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