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Mitochondrial CISD1/Cisd accumulation blocks mitophagy and genetic or pharmacological inhibition rescues neurodegenerative phenotypes in Pink1/parkin models

• Authors : Aitor Martinez; Alvaro Sanchez-Martinez; Jake T. Pickering

Subjects: CISD1; CISD2; Cisd

• Source: Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-21 (2024)

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Mitochondrial CISD1/Cisd accumulation blocks mitophagy and genetic or pharmacological inhibition rescues neurodegenerative phenotypes in Pink1/parkin models.

• Authors : Martinez, Aitor^1,2 (AUTHOR) ; Sanchez-Martinez, Alvaro¹ (AUTHOR); Pickering, Jake T.¹ (AUTHOR)

• Source: Molecular Neurodegeneration. 1/25/2024, Vol. 19 Issue 1, p1-21. 21p.

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Cholesterol alters mitophagy by impairing optineurin recruitment and lysosomal clearance in Alzheimer’s disease

• Authors : Vicente Roca-Agujetas; Elisabet Barbero-Camps; Cristina de Dios

Subjects: APP-PSEN1 mice; Mitochondria; Glutathione

• Source: Molecular Neurodegeneration, Vol 16, Iss 1, Pp 1-26 (2021)

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Cholesterol alters mitophagy by impairing optineurin recruitment and lysosomal clearance in Alzheimer's disease.

• Authors : Roca-Agujetas, Vicente^1,2 (AUTHOR); Barbero-Camps, Elisabet¹ (AUTHOR); de Dios, Cristina^1,2,3 (AUTHOR)

• Source: Molecular Neurodegeneration. 3/8/2021, Vol. 16 Issue 1, p1-26. 26p.

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Tauopathy-associated tau modifications selectively impact neurodegeneration and mitophagy in a novel C. elegans single-copy transgenic model

• Authors : Sanjib Guha; Sarah Fischer; Gail V. W. Johnson

Subjects: Alzheimer’s disease; C. elegans; Tau

• Source: Molecular Neurodegeneration, Vol 15, Iss 1, Pp 1-16 (2020)

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Tauopathy-associated tau modifications selectively impact neurodegeneration and mitophagy in a novel C. elegans single-copy transgenic model.

• Authors : Guha S; Department of Anesthesiology & Perioperative Medicine, Box 604, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY, 14642, USA.; Fischer S

Subjects: Mitophagy/Mitophagy/Mitophagy/*physiology ; Nerve Degeneration/Nerve Degeneration/Nerve Degeneration/*pathology ; Tauopathies/Tauopathies/Tauopathies/*pathology

• Source: Molecular neurodegeneration [Mol Neurodegener] 2020 Nov 09; Vol. 15 (1), pp. 65. Date of Electronic Publication: 2020 Nov 09.Publisher: BioMed Central Country of Publication: England NLM ID: 101266600 Publication Model: Electronic Cited Medium: Internet ISSN: 1750-1326

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Upregulation of Ca2+-binding proteins contributes to VTA dopamine neuron survival in the early phases of Alzheimer’s disease in Tg2576 mice

• Authors : Livia La Barbera; Annalisa Nobili; Emma Cauzzi

Subjects: Calbindin; Calretinin; Autophagy

• Source: Molecular Neurodegeneration, Vol 17, Iss 1, Pp 1-22 (2022)

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PINK1 and Parkin mitochondrial quality control: a source of regional vulnerability in Parkinson’s disease

• Authors : Preston Ge; Valina L. Dawson; Ted M. Dawson

Subjects: Parkinson disease; Parkin; PINK1

• Source: Molecular Neurodegeneration, Vol 15, Iss 1, Pp 1-18 (2020)

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Hexokinases link DJ-1 to the PINK1/parkin pathway

• Authors : David N. Hauser; Adamantios Mamais; Melissa M. Conti

Subjects: Proteomics; RNA-Seq; Metabolomics

• Source: Molecular Neurodegeneration, Vol 12, Iss 1, Pp 1-17 (2017)

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The PINK1 p.I368N mutation affects protein stability and ubiquitin kinase activity

• Authors : Maya Ando; Fabienne C. Fiesel; Roman Hudec

Subjects: Parkinson’s disease; PINK1; PARKIN

• Source: Molecular Neurodegeneration, Vol 12, Iss 1, Pp 1-19 (2017)

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