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Academic Journal

Astragaloside IV protects against autoimmune myasthenia gravis in rats via regulation of mitophagy and apoptosis.

Authors : Zhang J; Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510405, P.R. China.; Huang J

Subjects: Saponins*/Saponins*/Saponins*/pharmacology ; Apoptosis*/Apoptosis*/Apoptosis*/drug effects ; Triterpenes*/Triterpenes*/Triterpenes*/pharmacology

Source: Molecular medicine reports [Mol Med Rep] 2024 Jul; Vol. 30 (1). Date of Electronic Publication: 2024 May 24.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Antihypertension effect of astragaloside IV during cerebral ischemia reperfusion in rats.

Authors : Shen F; Department of Anesthesiology, Shenzhen Traditional Chinese Medicine Hospital, 4th Medical School of Guangzhou University of Traditional Chinese Medicine, Shenzhen, Guangdong 518033.; Meng Y

Subjects: Saponins*/Saponins*/Saponins*/pharmacology ; Saponins*/Saponins*/Saponins*/therapeutic use ; Triterpenes*/Triterpenes*/Triterpenes*/pharmacology

Source: Molecular medicine reports [Mol Med Rep] 2023 Jan; Vol. 27 (1). Date of Electronic Publication: 2022 Nov 04.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Exploration of the hepatoprotective effect and mechanism of magnesium isoglycyrrhizinate in mice with arsenic trioxide‑induced acute liver injury.

Authors : Liu M; Department of Pharmacology, School of Pharmacy, Hebei University of Chinese Medicine, Shijiazhuang, Hebei 050200, P.R. China.; Zheng B

Subjects: Arsenic Trioxide/Arsenic Trioxide/Arsenic Trioxide/*adverse effects ; Liver/Liver/Liver/*drug effects ; Liver/Liver/Liver/*injuries

Source: Molecular medicine reports [Mol Med Rep] 2021 Jun; Vol. 23 (6). Date of Electronic Publication: 2021 Apr 13.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Neuroprotective effect of tormentic acid against memory impairment and neuro‑inflammation in an Alzheimer's disease mouse model.

Authors : Cui W; Department of Human Anatomy, Xinxiang Medical University, Xinxiang, Henan 453003, P.R. China.; Sun C

Subjects: Alzheimer Disease/Alzheimer Disease/Alzheimer Disease/*drug therapy ; Inflammation/Inflammation/Inflammation/*metabolism ; Memory Disorders/Memory Disorders/Memory Disorders/*drug therapy

Source: Molecular medicine reports [Mol Med Rep] 2020 Aug; Vol. 22 (2), pp. 739-750. Date of Electronic Publication: 2020 May 18.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Autophagy flux inhibition mediated by celastrol sensitized lung cancer cells to TRAIL‑induced apoptosis via regulation of mitochondrial transmembrane potential and reactive oxygen species.

Authors : Nazim UM; Department of Biochemistry, Biosafety Research Institute, College of Veterinary Medicine, Chonbuk National University, Iksan, Jeonbuk 54596, Republic of Korea.; Yin H

Subjects: Gene Expression Regulation, Neoplastic*; Antineoplastic Agents, Phytogenic/Antineoplastic Agents, Phytogenic/Antineoplastic Agents, Phytogenic/*pharmacology ; Apoptosis/Apoptosis/Apoptosis/*drug effects

Source: Molecular medicine reports [Mol Med Rep] 2019 Feb; Vol. 19 (2), pp. 984-993. Date of Electronic Publication: 2018 Dec 12.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Asiaticoside produces an antidepressant‑like effect in a chronic unpredictable mild stress model of depression in mice, involving reversion of inflammation and the PKA/pCREB/BDNF signaling pathway.

Authors : Wang L; Department of Cardiovascular Medicine, The Second People's Hospital of Lianyungang, Lianyungang, Jiangsu 222000, P.R. China.; Guo T

Subjects: Antidepressive Agents/Antidepressive Agents/Antidepressive Agents/*administration & dosage ; Brain-Derived Neurotrophic Factor/Brain-Derived Neurotrophic Factor/Brain-Derived Neurotrophic Factor/*metabolism ; Cyclic AMP Response Element-Binding Protein/Cyclic AMP Response Element-Binding Protein/Cyclic AMP Response Element-Binding Protein/*metabolism

Source: Molecular medicine reports [Mol Med Rep] 2020 Sep; Vol. 22 (3), pp. 2364-2372. Date of Electronic Publication: 2020 Jul 06.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Celastrol inhibits glucocorticoid‑induced osteoporosis in rat via the PI3K/AKT and Wnt signaling pathways.

Authors : Xi J; Department of Minimally Invasive Spine Surgery, The 309th Hospital of the People's Liberation Army, Beijing 100091, P.R. China.; Li Q

Subjects: Osteoporosis/Osteoporosis/Osteoporosis/*drug therapy ; Osteoporosis/Osteoporosis/Osteoporosis/*genetics ; Triterpenes/Triterpenes/Triterpenes/*administration & dosage

Source: Molecular medicine reports [Mol Med Rep] 2018 Nov; Vol. 18 (5), pp. 4753-4759. Date of Electronic Publication: 2018 Sep 03.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Axl is a novel target of celastrol that inhibits cell proliferation and migration, and increases the cytotoxicity of gefitinib in EGFR mutant non‑small cell lung cancer cells.

Authors : Lee YJ; Department of Pharmacology, College of Medicine, Catholic University of Daegu, Daegu 42472, Republic of Korea.; Kim SY

Subjects: Mutation*; Carcinoma, Non-Small-Cell Lung/Carcinoma, Non-Small-Cell Lung/Carcinoma, Non-Small-Cell Lung/*genetics ; Gefitinib/Gefitinib/Gefitinib/*pharmacology

Source: Molecular medicine reports [Mol Med Rep] 2019 Apr; Vol. 19 (4), pp. 3230-3236. Date of Electronic Publication: 2019 Feb 14.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Combination of pristimerin and paclitaxel additively induces autophagy in human breast cancer cells via ERK1/2 regulation.

Authors : Lee Y; Department of Surgery, Chungnam National University Hospital, Jung‑gu, Daejeon 35015, Republic of Korea.; Na J

Subjects: Autophagy/Autophagy/Autophagy/*drug effects ; Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*metabolism ; Mitogen-Activated Protein Kinase 1/Mitogen-Activated Protein Kinase 1/Mitogen-Activated Protein Kinase 1/*metabolism

Source: Molecular medicine reports [Mol Med Rep] 2018 Nov; Vol. 18 (5), pp. 4281-4288. Date of Electronic Publication: 2018 Sep 14.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Astragaloside IV prevents high glucose‑induced cell apoptosis and inflammatory reactions through inhibition of the JNK pathway in human umbilical vein endothelial cells.

Authors : You L; Graduate Institute, Anhui University of Chinese Medicine, Hefei, Anhui 230031, P.R. China.; Fang Z

Subjects: Astragalus propinquus/Astragalus propinquus/Astragalus propinquus/*chemistry ; Inflammation/Inflammation/Inflammation/*drug therapy ; MAP Kinase Signaling System/MAP Kinase Signaling System/MAP Kinase Signaling System/*drug effects

Source: Molecular medicine reports [Mol Med Rep] 2019 Mar; Vol. 19 (3), pp. 1603-1612. Date of Electronic Publication: 2019 Jan 03.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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نتائج البحث

فلترة النتائج

Astragaloside IV protects against autoimmune myasthenia gravis in rats via regulation of mitophagy and apoptosis.

Antihypertension effect of astragaloside IV during cerebral ischemia reperfusion in rats.

Exploration of the hepatoprotective effect and mechanism of magnesium isoglycyrrhizinate in mice with arsenic trioxide‑induced acute liver injury.

Neuroprotective effect of tormentic acid against memory impairment and neuro‑inflammation in an Alzheimer's disease mouse model.

Autophagy flux inhibition mediated by celastrol sensitized lung cancer cells to TRAIL‑induced apoptosis via regulation of mitochondrial transmembrane potential and reactive oxygen species.

Asiaticoside produces an antidepressant‑like effect in a chronic unpredictable mild stress model of depression in mice, involving reversion of inflammation and the PKA/pCREB/BDNF signaling pathway.

Celastrol inhibits glucocorticoid‑induced osteoporosis in rat via the PI3K/AKT and Wnt signaling pathways.

Axl is a novel target of celastrol that inhibits cell proliferation and migration, and increases the cytotoxicity of gefitinib in EGFR mutant non‑small cell lung cancer cells.

Combination of pristimerin and paclitaxel additively induces autophagy in human breast cancer cells via ERK1/2 regulation.

Astragaloside IV prevents high glucose‑induced cell apoptosis and inflammatory reactions through inhibition of the JNK pathway in human umbilical vein endothelial cells.

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