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Academic Journal

Tanshinone IIA promotes osteogenic differentiation potential and suppresses adipogenic differentiation potential of bone marrow mesenchymal stem cells.

  • Authors : Wang W; Department of Orthopedics, Hubei Provincial Hospital of Traditional Chinese Medicine, Wuhan, Hubei 430074, P.R. China.; Wu H

Subjects: Mesenchymal Stem Cells*/Mesenchymal Stem Cells*/Mesenchymal Stem Cells*/drug effects ; Mesenchymal Stem Cells*/Mesenchymal Stem Cells*/Mesenchymal Stem Cells*/metabolism ; Mesenchymal Stem Cells*/Mesenchymal Stem Cells*/Mesenchymal Stem Cells*/cytology

  • Source: Molecular medicine reports [Mol Med Rep] 2024 Oct; Vol. 30 (4). Date of Electronic Publication: 2024 Aug 12.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Tanshinone IIA regulates expression of glucose transporter 1 via activation of the HIF‑1α signaling pathway.

  • Authors : Zhou Y; Central Laboratory, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200062, P.R. China.; Zhang H

Subjects: Abietanes*/Abietanes*/Abietanes*/pharmacology ; Endothelial Cells*/Endothelial Cells*/Endothelial Cells*/metabolism ; Salvia miltiorrhiza*/Salvia miltiorrhiza*/Salvia miltiorrhiza*/chemistry

  • Source: Molecular medicine reports [Mol Med Rep] 2022 Nov; Vol. 26 (5). Date of Electronic Publication: 2022 Sep 07.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Tanshinone I and simvastatin inhibit melanoma tumour cell growth by regulating poly (ADP ribose) polymerase 1 expression.

  • Authors : Zhang Y; Department of Pharmacy, Guangzhou Institute of Dermatology, Guangzhou, Guangdong 510095, P.R. China.; Huang J

Subjects: Abietanes/Abietanes/Abietanes/*administration & dosage ; Antineoplastic Combined Chemotherapy Protocols/Antineoplastic Combined Chemotherapy Protocols/Antineoplastic Combined Chemotherapy Protocols/*administration & dosage ; Melanoma/Melanoma/Melanoma/*drug therapy

  • Source: Molecular medicine reports [Mol Med Rep] 2021 Jan; Vol. 23 (1). Date of Electronic Publication: 2020 Nov 12.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Identifying the mechanisms underlying the protective effect of tetramethylpyrazine against cisplatin‑induced in vitro ototoxicity in HEI‑OC1 auditory cells using gene expression profiling.

  • Authors : Guan G; Department of Otolaryngology, The Second Hospital of Jilin University, Changchun, Jilin 130041, P.R. China.; He X

Subjects: Abietanes/Abietanes/Abietanes/*pharmacology ; Hearing Loss, Sensorineural/Hearing Loss, Sensorineural/Hearing Loss, Sensorineural/*metabolism ; Pyrazines/Pyrazines/Pyrazines/*pharmacology

  • Source: Molecular medicine reports [Mol Med Rep] 2020 Dec; Vol. 22 (6), pp. 5053-5068. Date of Electronic Publication: 2020 Oct 23.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Carnosic acid alleviates brain injury through NF‑κB‑regulated inflammation and Caspase‑3‑associated apoptosis in high fat‑induced mouse models.

  • Authors : Liu Y; Department of Anesthesiology, Traditional Chinese Medicine Hospital Affiliated to Xinjiang Medical University, Urumqi, Xinjiang 830099, P.R. China.; Zhang Y

Subjects: Abietanes/Abietanes/Abietanes/*therapeutic use ; Anti-Inflammatory Agents/Anti-Inflammatory Agents/Anti-Inflammatory Agents/*therapeutic use ; Brain Injuries/Brain Injuries/Brain Injuries/*drug therapy

  • Source: Molecular medicine reports [Mol Med Rep] 2019 Jul; Vol. 20 (1), pp. 495-504. Date of Electronic Publication: 2019 May 27.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Tanshinone IIA induces apoptosis via inhibition of Wnt/β‑catenin/MGMT signaling in AtT‑20 cells.

  • Authors : Li ZY; Brain Center, Shenzhen Key Laboratory of Neurosurgery, Shenzhen Second People's Hospital, Shenzhen University 1st Affiliated Hospital, Shenzhen, Guangdong 518035, P.R. China.; Huang GD

Subjects: Gene Expression Regulation, Neoplastic*; Abietanes/Abietanes/Abietanes/*pharmacology ; Antineoplastic Agents, Phytogenic/Antineoplastic Agents, Phytogenic/Antineoplastic Agents, Phytogenic/*pharmacology

  • Source: Molecular medicine reports [Mol Med Rep] 2017 Nov; Vol. 16 (5), pp. 5908-5914. Date of Electronic Publication: 2017 Aug 22.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Ferruginol exhibits anticancer effects in OVCAR‑3 human ovary cancer cells by inducing apoptosis, inhibition of cancer cell migration and G2/M phase cell cycle arrest.

  • Authors : Xiong WD; Department of Obstetrics and Gynecology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325027, P.R. China.; Gong J

Subjects: Abietanes/Abietanes/Abietanes/*toxicity ; Antineoplastic Agents, Phytogenic/Antineoplastic Agents, Phytogenic/Antineoplastic Agents, Phytogenic/*toxicity ; Apoptosis/Apoptosis/Apoptosis/*drug effects

  • Source: Molecular medicine reports [Mol Med Rep] 2017 Nov; Vol. 16 (5), pp. 7013-7017. Date of Electronic Publication: 2017 Sep 13.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Articular cartilage degradation is prevented by tanshinone IIA through inhibiting apoptosis and the expression of inflammatory cytokines.

  • Authors : Jia PT; Department of Orthopedics, Yantaishan Hospital, Yantai, Shandong 264001, P.R. China.; Zhang XL

Subjects: Abietanes/Abietanes/Abietanes/*pharmacology ; Apoptosis/Apoptosis/Apoptosis/*drug effects ; Cartilage, Articular/Cartilage, Articular/Cartilage, Articular/*drug effects

  • Source: Molecular medicine reports [Mol Med Rep] 2017 Nov; Vol. 16 (5), pp. 6285-6289. Date of Electronic Publication: 2017 Aug 23.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Tanshinone IIA increases protein expression levels of PERK, ATF6, IRE1α, CHOP, caspase‑3 and caspase‑12 in pancreatic cancer BxPC‑3 cell‑derived xenograft tumors.

  • Authors : Chiu TL; Division of Neurooncology, Neuro‑Medical Scientific Center, Buddhist Tzu‑Chi General Hospital, Hualien 97004, Taiwan, R.O.C.; Su CC

Subjects: Abietanes/Abietanes/Abietanes/*toxicity ; Activating Transcription Factor 6/Activating Transcription Factor 6/Activating Transcription Factor 6/*metabolism ; Antineoplastic Agents, Phytogenic/Antineoplastic Agents, Phytogenic/Antineoplastic Agents, Phytogenic/*toxicity

  • Source: Molecular medicine reports [Mol Med Rep] 2017 May; Vol. 15 (5), pp. 3259-3263. Date of Electronic Publication: 2017 Mar 22.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Effects of tanshinone IIA on fibrosis in a rat model of cirrhosis through heme oxygenase-1, inflammation, oxidative stress and apoptosis.

  • Authors : Shu M; Department of Hepatobiliary Surgery, Ningbo No. 2 Hospital, Ningbo, Zhejiang 315010, P.R. China.; Hu XR

Subjects: Abietanes/Abietanes/Abietanes/*pharmacology ; Anti-Inflammatory Agents, Non-Steroidal/Anti-Inflammatory Agents, Non-Steroidal/Anti-Inflammatory Agents, Non-Steroidal/*pharmacology ; Apoptosis/Apoptosis/Apoptosis/*drug effects

  • Source: Molecular medicine reports [Mol Med Rep] 2016 Apr; Vol. 13 (4), pp. 3036-42. Date of Electronic Publication: 2016 Feb 10.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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