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Academic Journal

Chimeric antigen receptor macrophages targeting c-MET(CAR-M-c-MET) inhibit pancreatic cancer progression and improve cytotoxic chemotherapeutic efficacy.

  • Authors : Zheng H; Department of General Surgery, State Key Laboratory of Complex Severe and Rare Diseases, Dongcheng District, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, No.1 Shuai Fu Yuan, Beijing, 100730, China.; Yang X

Subjects: Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/therapy ; Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/pathology ; Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/immunology

  • Source: Molecular cancer [Mol Cancer] 2024 Dec 06; Vol. 23 (1), pp. 270. Date of Electronic Publication: 2024 Dec 06.Publisher: BioMed Central Country of Publication: England NLM ID: 101147698 Publication Model: Electronic Cited Medium: Internet ISSN: 1476-4598

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Academic Journal

Liquid biopsy techniques and pancreatic cancer: diagnosis, monitoring, and evaluation.

  • Authors : Wang K; Department of Organ Transplantation and Hepatobiliary, The First Affiliated Hospital of China Medical University, Shenyang, 110001, China.; Wang X

Subjects: Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/diagnosis ; Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/genetics ; Neoplastic Cells, Circulating*/Neoplastic Cells, Circulating*/Neoplastic Cells, Circulating*/pathology

  • Source: Molecular cancer [Mol Cancer] 2023 Oct 06; Vol. 22 (1), pp. 167. Date of Electronic Publication: 2023 Oct 06.Publisher: BioMed Central Country of Publication: England NLM ID: 101147698 Publication Model: Electronic Cited Medium: Internet ISSN: 1476-4598

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Ultra-sensitive CTC-based liquid biopsy for pancreatic cancer enabled by large blood volume analysis.

  • Authors : Stoecklein NH; General, Visceral and Pediatric Surgery, University Hospital and Medical Faculty of the Heinrich-Heine-University Düsseldorf, Moorenstr. 5, 40225, Düsseldorf, Germany. .; Fluegen G

Subjects: Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/diagnosis ; Adenocarcinoma*/Adenocarcinoma*/Adenocarcinoma*/diagnosis ; Neoplastic Cells, Circulating*/Neoplastic Cells, Circulating*/Neoplastic Cells, Circulating*/pathology

  • Source: Molecular cancer [Mol Cancer] 2023 Nov 13; Vol. 22 (1), pp. 181. Date of Electronic Publication: 2023 Nov 13.Publisher: BioMed Central Country of Publication: England NLM ID: 101147698 Publication Model: Electronic Cited Medium: Internet ISSN: 1476-4598

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Academic Journal

Sulindac (K-80003) with nab-paclitaxel and gemcitabine overcomes drug-resistant pancreatic cancer.

  • Authors : Xie CK; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China.; Department of Hepatobiliary Pancreatic Surgery, Fuzhou University Affiliated Provincial Hospital, Fujian Provincial Hospital, Fuzhou, 350001, China.

Subjects: Deoxycytidine*/Deoxycytidine*/Deoxycytidine*/analogs & derivatives ; Deoxycytidine*/Deoxycytidine*/Deoxycytidine*/pharmacology ; Gemcitabine*

  • Source: Molecular cancer [Mol Cancer] 2024 Sep 30; Vol. 23 (1), pp. 215. Date of Electronic Publication: 2024 Sep 30.Publisher: BioMed Central Country of Publication: England NLM ID: 101147698 Publication Model: Electronic Cited Medium: Internet ISSN: 1476-4598

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Academic Journal

Unbiasedly decoding the tumor microenvironment with single-cell multiomics analysis in pancreatic cancer.

  • Authors : Fu Y; General Surgery Department, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, China.; 4+4 Medical Doctor Program, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, China.

Subjects: Tumor Microenvironment*/Tumor Microenvironment*/Tumor Microenvironment*/genetics ; Single-Cell Analysis*/Single-Cell Analysis*/Single-Cell Analysis*/methods ; Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/genetics

  • Source: Molecular cancer [Mol Cancer] 2024 Jul 09; Vol. 23 (1), pp. 140. Date of Electronic Publication: 2024 Jul 09.Publisher: BioMed Central Country of Publication: England NLM ID: 101147698 Publication Model: Electronic Cited Medium: Internet ISSN: 1476-4598

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Academic Journal

circEIF3I facilitates the recruitment of SMAD3 to early endosomes to promote TGF-β signalling pathway-mediated activation of MMPs in pancreatic cancer.

  • Authors : Zhao Z; Department of Pancreatic and Biliary Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, 150001, Heilongjiang, China.; Key Laboratory of Hepatosplenic Surgery, Ministry of Education, The First Affiliated Hospital of Harbin Medical University, Harbin, 150001, Heilongjiang, China.

Subjects: Carcinoma, Pancreatic Ductal*/Carcinoma, Pancreatic Ductal*/Carcinoma, Pancreatic Ductal*/genetics ; Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/genetics; Animals

  • Source: Molecular cancer [Mol Cancer] 2023 Sep 09; Vol. 22 (1), pp. 152. Date of Electronic Publication: 2023 Sep 09.Publisher: BioMed Central Country of Publication: England NLM ID: 101147698 Publication Model: Electronic Cited Medium: Internet ISSN: 1476-4598

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Academic Journal

The phospholipid transporter PITPNC1 links KRAS to MYC to prevent autophagy in lung and pancreatic cancer.

  • Authors : Entrialgo-Cadierno R; Program in Solid Tumours, University of Navarra, Centre of Applied Medical Research (CIMA), 55 Pio XII Avenue, 31008, Pamplona, Spain.; Cueto-Ureña C

Subjects: Carcinoma, Pancreatic Ductal*/Carcinoma, Pancreatic Ductal*/Carcinoma, Pancreatic Ductal*/pathology ; Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/pathology ; Membrane Transport Proteins*/Membrane Transport Proteins*/Membrane Transport Proteins*/genetics

  • Source: Molecular cancer [Mol Cancer] 2023 May 20; Vol. 22 (1), pp. 86. Date of Electronic Publication: 2023 May 20.Publisher: BioMed Central Country of Publication: England NLM ID: 101147698 Publication Model: Electronic Cited Medium: Internet ISSN: 1476-4598

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Academic Journal

Unravelling the enigma of siRNA and aptamer mediated therapies against pancreatic cancer.

  • Authors : Liu Z; Department of Pancreatic-Biliary Surgery, The First Hospital of China Medical University, Shenyang, China.; Parveen N

Subjects: Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/therapeutic use ; Aptamers, Nucleotide*/Aptamers, Nucleotide*/Aptamers, Nucleotide*/genetics ; Aptamers, Nucleotide*/Aptamers, Nucleotide*/Aptamers, Nucleotide*/therapeutic use

  • Source: Molecular cancer [Mol Cancer] 2023 Jan 12; Vol. 22 (1), pp. 8. Date of Electronic Publication: 2023 Jan 12.Publisher: BioMed Central Country of Publication: England NLM ID: 101147698 Publication Model: Electronic Cited Medium: Internet ISSN: 1476-4598

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Academic Journal

Positive feedback regulation between glycolysis and histone lactylation drives oncogenesis in pancreatic ductal adenocarcinoma.

  • Authors : Li F; Department of Endocrinology and Metabolism, State Key Laboratory of Female Fertility Promotion, Peking University Third Hospital, Beijing, 100191, China.; Si W

Subjects: Carcinoma, Pancreatic Ductal*/Carcinoma, Pancreatic Ductal*/Carcinoma, Pancreatic Ductal*/metabolism ; Carcinoma, Pancreatic Ductal*/Carcinoma, Pancreatic Ductal*/Carcinoma, Pancreatic Ductal*/pathology ; Carcinoma, Pancreatic Ductal*/Carcinoma, Pancreatic Ductal*/Carcinoma, Pancreatic Ductal*/genetics

  • Source: Molecular cancer [Mol Cancer] 2024 May 06; Vol. 23 (1), pp. 90. Date of Electronic Publication: 2024 May 06.Publisher: BioMed Central Country of Publication: England NLM ID: 101147698 Publication Model: Electronic Cited Medium: Internet ISSN: 1476-4598

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Academic Journal

Single-cell transcriptome analysis reveals subtype-specific clonal evolution and microenvironmental changes in liver metastasis of pancreatic adenocarcinoma and their clinical implications.

  • Authors : Park JK; Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.; Department of Health Sciences and Technology, Samsung Advanced Institute for Health Sciences & Technology (SAIHST), Sungkyunkwan University, Seoul, Republic of Korea.

Subjects: Clonal Evolution*/Clonal Evolution*/Clonal Evolution*/genetics ; Liver Neoplasms*/Liver Neoplasms*/Liver Neoplasms*/secondary ; Liver Neoplasms*/Liver Neoplasms*/Liver Neoplasms*/genetics

  • Source: Molecular cancer [Mol Cancer] 2024 May 03; Vol. 23 (1), pp. 87. Date of Electronic Publication: 2024 May 03.Publisher: BioMed Central Country of Publication: England NLM ID: 101147698 Publication Model: Electronic Cited Medium: Internet ISSN: 1476-4598

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