نتائج البحث

Loss of mitochondrial enzyme GPT2 leads to reprogramming of synaptic glutamate metabolism.

• Authors : Baytas O; Department of Molecular Biology, Cell Biology and Biochemistry, Laboratories for Molecular Medicine, Brown University, 70 Ship Street, Providence, RI, 02912, USA.; Center for Translational Neuroscience, Carney Institute for Brain Science and Brown Institute for Translational Science, Brown University, Providence, RI, 02912, USA.

Subjects: Glutamic Acid*/Glutamic Acid*/Glutamic Acid*/metabolism ; Mitochondria*/Mitochondria*/Mitochondria*/metabolism ; Synapses*/Synapses*/Synapses*/metabolism

• Source: Molecular brain [Mol Brain] 2024 Nov 27; Vol. 17 (1), pp. 87. Date of Electronic Publication: 2024 Nov 27.Publisher: BioMed Central Country of Publication: England NLM ID: 101468876 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-6606

تفاصيل العنوان

Transcriptomic changes in oligodendrocytes and precursor cells associate with clinical outcomes of Parkinson's disease.

• Authors : Dehestani M; German Center for Neurodegenerative Diseases (DZNE), Tuebingen, Germany.; Department of Neurodegeneration, Hertie Institute for Clinical Brain Research, University of Tuebingen, Tuebingen, Germany.

Subjects: Parkinson Disease*/Parkinson Disease*/Parkinson Disease*/genetics ; Parkinson Disease*/Parkinson Disease*/Parkinson Disease*/pathology ; Oligodendroglia*/Oligodendroglia*/Oligodendroglia*/metabolism

• Source: Molecular brain [Mol Brain] 2024 Aug 13; Vol. 17 (1), pp. 56. Date of Electronic Publication: 2024 Aug 13.Publisher: BioMed Central Country of Publication: England NLM ID: 101468876 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-6606

تفاصيل العنوان

Enhanced primary ciliogenesis via mitochondrial oxidative stress activates AKT to prevent neurotoxicity in HSPA9/mortalin-depleted SH-SY5Y cells.

• Authors : Bae, Ji-Eun¹ (AUTHOR); Jang, Soyoung² (AUTHOR); Kim, Joon Bum² (AUTHOR)

• Source: Molecular Brain. 5/11/2023, Vol. 16 Issue 1, p1-10. 10p.

تفاصيل العنوان

Impaired mitochondrial accumulation and Lewy pathology in neuron-specific FBXO7-deficient mice.

• Authors : Noda S; Department of Neurology, Juntendo University Graduate School of Medicine, Tokyo, 113-8421, Japan.; Sato S

Subjects: F-Box Proteins*/F-Box Proteins*/F-Box Proteins*/genetics ; F-Box Proteins*/F-Box Proteins*/F-Box Proteins*/metabolism ; Lewy Bodies*/Lewy Bodies*/Lewy Bodies*/metabolism

• Source: Molecular brain [Mol Brain] 2022 Jun 14; Vol. 15 (1), pp. 54. Date of Electronic Publication: 2022 Jun 14.Publisher: BioMed Central Country of Publication: England NLM ID: 101468876 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-6606

تفاصيل العنوان

Acute inhibition of OGA sex-dependently alters the networks associated with bioenergetics, autophagy, and neurodegeneration.

• Authors : Huynh VN; Department of Pathology, Center for Free Radical Biology, University of Alabama at Birmingham, BMRII-534, 901 19th Street S., Birmingham, AL, 35294-0017, USA.; Benavides GA

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/metabolism ; Neurodegenerative Diseases*; Animals

• Source: Molecular brain [Mol Brain] 2022 Mar 05; Vol. 15 (1), pp. 22. Date of Electronic Publication: 2022 Mar 05.Publisher: BioMed Central Country of Publication: England NLM ID: 101468876 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-6606

تفاصيل العنوان

Loss of Drosophila Coq8 results in impaired survival, locomotor deficits and photoreceptor degeneration.

• Authors : Hura AJ; School of Natural Sciences, Massey University, Palmerston North, New Zealand.; Hawley HR

Subjects: Mitochondrial Diseases*/Mitochondrial Diseases*/Mitochondrial Diseases*/genetics ; Saccharomyces cerevisiae Proteins*/Saccharomyces cerevisiae Proteins*/Saccharomyces cerevisiae Proteins*/metabolism; Animals

• Source: Molecular brain [Mol Brain] 2022 Feb 09; Vol. 15 (1), pp. 15. Date of Electronic Publication: 2022 Feb 09.Publisher: BioMed Central Country of Publication: England NLM ID: 101468876 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-6606

تفاصيل العنوان

Astrocyte metabolism of the medium-chain fatty acids octanoic acid and decanoic acid promotes GABA synthesis in neurons via elevated glutamine supply.

• Authors : Andersen JV; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100, Copenhagen E, Denmark. .; Westi EW

Subjects: Astrocytes/Astrocytes/Astrocytes/*metabolism ; Caprylates/Caprylates/Caprylates/*metabolism ; Cerebral Cortex/Cerebral Cortex/Cerebral Cortex/*metabolism

• Source: Molecular brain [Mol Brain] 2021 Sep 03; Vol. 14 (1), pp. 132. Date of Electronic Publication: 2021 Sep 03.Publisher: BioMed Central Country of Publication: England NLM ID: 101468876 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-6606

تفاصيل العنوان

Cocaine-induced neuron subtype mitochondrial dynamics through Egr3 transcriptional regulation.

• Authors : Cole SL; Department of Anatomy and Neurobiology, University of Maryland School of Medicine, HSF II Rm S265, 20 Penn Street, Baltimore, MD, 21201, USA.; Chandra R

Subjects: Gene Expression Regulation*/Gene Expression Regulation*/Gene Expression Regulation*/drug effects ; Transcription, Genetic*/Transcription, Genetic*/Transcription, Genetic*/drug effects; Cocaine/Cocaine/Cocaine/*pharmacology

• Source: Molecular brain [Mol Brain] 2021 Jun 29; Vol. 14 (1), pp. 101. Date of Electronic Publication: 2021 Jun 29.Publisher: BioMed Central Country of Publication: England NLM ID: 101468876 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-6606

تفاصيل العنوان

Cdk5 regulatory subunit-associated protein 1 knockout mice show hearing loss phenotypically similar to age-related hearing loss.

• Authors : Miwa T; Department of Otolaryngology-Head and Neck Surgery, Graduate School of Medicine, Kyoto University, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 6068507, Japan. .; Department of Otolaryngology-Head and Neck Surgery, Kitano Hospital, Tazuke Kofukai Medical Research Institute, 2-4-20 Ougimaci, Kita-ku, Osaka, 5308480, Japan. .

Subjects: Aging/Aging/Aging/*pathology ; Cell Cycle Proteins/Cell Cycle Proteins/Cell Cycle Proteins/*deficiency ; Mitochondrial Proteins/Mitochondrial Proteins/Mitochondrial Proteins/*genetics

• Source: Molecular brain [Mol Brain] 2021 May 17; Vol. 14 (1), pp. 82. Date of Electronic Publication: 2021 May 17.Publisher: BioMed Central Country of Publication: England NLM ID: 101468876 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-6606

تفاصيل العنوان

FMRP attenuates activity dependent modifications in the mitochondrial proteome.

• Authors : Bülow P; Department of Cell Biology, Emory University School of Medicine, Atlanta, GA, 30322, USA.; Zlatic SA

Subjects: Fragile X Mental Retardation Protein/Fragile X Mental Retardation Protein/Fragile X Mental Retardation Protein/*metabolism ; Mitochondrial Proteins/Mitochondrial Proteins/Mitochondrial Proteins/*metabolism ; Proteome/Proteome/Proteome/*metabolism

• Source: Molecular brain [Mol Brain] 2021 Apr 30; Vol. 14 (1), pp. 75. Date of Electronic Publication: 2021 Apr 30.Publisher: BioMed Central Country of Publication: England NLM ID: 101468876 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-6606

تفاصيل العنوان