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  • 1-10 ل  47 نتائج ل ""Cytochrome P-450 CYP2D6""
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Academic Journal

A single low dose of primaquine is safe and sufficient to reduce transmission of Plasmodium falciparum gametocytes regardless of cytochrome P450 2D6 enzyme activity in Bagamoyo district, Tanzania.

  • Authors : Mwaiswelo RO; Department of Research and Training, Tropical Pesticides Research Institute, Arusha, Tanzania. .; Department of Microbiology, Immunology and Parasitology, Hubert Kairuki Memorial University, Dar es Salaam, Tanzania. .

Subjects: Antimalarials*/Antimalarials*/Antimalarials*/therapeutic use ; Cytochrome P-450 CYP2D6*/Cytochrome P-450 CYP2D6*/Cytochrome P-450 CYP2D6*/genetics; Artemether

  • Source: Malaria journal [Malar J] 2022 Mar 12; Vol. 21 (1), pp. 84. Date of Electronic Publication: 2022 Mar 12.Publisher: BioMed Central Country of Publication: England NLM ID: 101139802 Publication Model: Electronic Cited Medium: Internet ISSN: 1475-2875

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Academic Journal

Cytochrome P450 2D6 profiles and their relationship with outcomes of primaquine anti-relapse therapy in Australian Defence Force personnel deployed to Papua New Guinea and East Timor.

  • Authors : Chen N; Australian Defence Force Malaria and Infectious Disease Institute, Brisbane, QLD, Australia.; Dowd S

Subjects: Antimalarials/Antimalarials/Antimalarials/*therapeutic use ; Cytochrome P-450 CYP2D6/Cytochrome P-450 CYP2D6/Cytochrome P-450 CYP2D6/*genetics ; Malaria, Vivax/Malaria, Vivax/Malaria, Vivax/*drug therapy

  • Source: Malaria journal [Malar J] 2019 Apr 18; Vol. 18 (1), pp. 140. Date of Electronic Publication: 2019 Apr 18.Publisher: BioMed Central Country of Publication: England NLM ID: 101139802 Publication Model: Electronic Cited Medium: Internet ISSN: 1475-2875

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Academic Journal

Primaquine ineligibility in anti-relapse therapy of Plasmodium vivax malaria: the problem of G6PD deficiency and cytochrome P-450 2D6 polymorphisms.

  • Authors : Baird JK; Eijkman-Oxford Clinical Research Unit, Jalan Diponegoro No.69, Central Jakarta, 10430, Indonesia.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Old Road Campus, Oxford, OX3 7FZ, UK.

Subjects: Polymorphism, Single Nucleotide*; Antimalarials/Antimalarials/Antimalarials/*therapeutic use ; Cytochrome P-450 CYP2D6/Cytochrome P-450 CYP2D6/Cytochrome P-450 CYP2D6/*genetics

  • Source: Malaria journal [Malar J] 2018 Jan 22; Vol. 17 (1), pp. 42. Date of Electronic Publication: 2018 Jan 22.Publisher: BioMed Central Country of Publication: England NLM ID: 101139802 Publication Model: Electronic Cited Medium: Internet ISSN: 1475-2875

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Academic Journal

Cytochrome P450 2D-mediated metabolism is not necessary for tafenoquine and primaquine to eradicate the erythrocytic stages of Plasmodium berghei.

  • Authors : Milner EE; Walter Reed Army Institute of Research (WRAIR), Silver Spring, MD, USA. .; Berman J

Subjects: Aminoquinolines/Aminoquinolines/Aminoquinolines/*pharmacology ; Antimalarials/Antimalarials/Antimalarials/*pharmacology ; Cytochrome P-450 CYP2D6/Cytochrome P-450 CYP2D6/Cytochrome P-450 CYP2D6/*metabolism

  • Source: Malaria journal [Malar J] 2016 Dec 07; Vol. 15 (1), pp. 588. Date of Electronic Publication: 2016 Dec 07.Publisher: BioMed Central Country of Publication: England NLM ID: 101139802 Publication Model: Electronic Cited Medium: Internet ISSN: 1475-2875

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Academic Journal

Tafenoquine and NPC-1161B require CYP 2D metabolism for anti-malarial activity: implications for the 8-aminoquinoline class of anti-malarial compounds.

  • Authors : Marcsisin SR; Division of Experimental Therapeutics, Military Malaria Research Program, Walter Reed Army Institute of Research, 503 Robert Grant Ave, Silver Spring, MD 20910, USA. .; Sousa JC

Subjects: Aminoquinolines/Aminoquinolines/Aminoquinolines/*metabolism ; Antimalarials/Antimalarials/Antimalarials/*metabolism ; Cytochrome P-450 CYP2D6/Cytochrome P-450 CYP2D6/Cytochrome P-450 CYP2D6/*metabolism

  • Source: Malaria journal [Malar J] 2014 Jan 03; Vol. 13, pp. 2. Date of Electronic Publication: 2014 Jan 03.Publisher: BioMed Central Country of Publication: England NLM ID: 101139802 Publication Model: Electronic Cited Medium: Internet ISSN: 1475-2875

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  • 1-10 ل  47 نتائج ل ""Cytochrome P-450 CYP2D6""