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Publication : leukemia (08876924)

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Academic Journal

The synergy of panobinostat plus doxorubicin in acute myeloid leukemia suggests a role for HDAC inhibitors in the control of DNA repair.

Authors : Maiso, P.¹ p@hotmail.com; Colado, E.²; Ocio, E. M.^1,2

Source: Leukemia (08876924). Dec2009, Vol. 23 Issue 12, p2265-2274. 10p. 1 Black and White Photograph, 1 Diagram, 2 Charts, 3 Graphs.

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Phase Ia/II, two-arm, open-label, dose-escalation study of oral panobinostat administered via two dosing schedules in patients with advanced hematologic malignancies.

Authors : DeAngelo, D J¹; Spencer, A²; Bhalla, K N³

Source: Leukemia (08876924). Aug2013, Vol. 27 Issue 8, p1628-1636. 9p. 1 Diagram, 6 Charts, 1 Graph.

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Phase 2 study of oral panobinostat (LBH589) with or without erythropoietin in heavily transfusion-dependent IPSS low or int-1 MDS patients.

Authors : Platzbecker, U¹; Al-Ali, H K²; Gattermann, N³

Source: Leukemia (08876924). Mar2014, Vol. 28 Issue 3, p696-698. 3p.

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Rapid recovery from panobinostat (LBH589)-induced thrombocytopenia in mice involves a rebound effect of bone marrow megakaryocytes.

Authors : Giver, C. R.^1,2 ; Jaye, D. L.³; Waller, E. K.^1,2

Source: Leukemia (08876924). Feb2011, Vol. 25 Issue 2, p362-365. 4p. 3 Graphs.

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Pre-clinical efficacy of combined therapy with novel β-catenin antagonist BC2059 and histone deacetylase inhibitor against AML cells.

Authors : Fiskus, W¹; Sharma, S²; Saha, S¹

Source: Leukemia (08876924). Jun2015, Vol. 29 Issue 6, p1267-1278. 12p. 1 Diagram, 6 Graphs.

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Academic Journal

Novel drugs for older patients with acute myeloid leukemia.

Authors : Montalban-Bravo, G¹; Garcia-Manero, G²

Source: Leukemia (08876924). Apr2015, Vol. 29 Issue 4, p760-769. 10p. 1 Diagram, 1 Chart.

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Highly effective combination of LSD1 (KDM1A) antagonist and pan-histone deacetylase inhibitor against human AML cells.

Authors : Fiskus, W¹; Sharma, S²; Shah, B¹

Source: Leukemia (08876924). Nov2014, Vol. 28 Issue 11, p2155-2164. 10p. 7 Graphs.

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Regulation of STAT3 by histone deacetylase-3 in diffuse large B-cell lymphoma: implications for therapy.

Authors : Gupta, M¹; Han, J J¹; Stenson, M¹

Source: Leukemia (08876924). Jun2012, Vol. 26 Issue 6, p1356-1364. 9p. 2 Color Photographs, 3 Black and White Photographs, 2 Graphs.

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فلترة النتائج

The synergy of panobinostat plus doxorubicin in acute myeloid leukemia suggests a role for HDAC inhibitors in the control of DNA repair.

Phase Ia/II, two-arm, open-label, dose-escalation study of oral panobinostat administered via two dosing schedules in patients with advanced hematologic malignancies.

Phase 2 study of oral panobinostat (LBH589) with or without erythropoietin in heavily transfusion-dependent IPSS low or int-1 MDS patients.

Rapid recovery from panobinostat (LBH589)-induced thrombocytopenia in mice involves a rebound effect of bone marrow megakaryocytes.

Pre-clinical efficacy of combined therapy with novel β-catenin antagonist BC2059 and histone deacetylase inhibitor against AML cells.

Novel drugs for older patients with acute myeloid leukemia.

Highly effective combination of LSD1 (KDM1A) antagonist and pan-histone deacetylase inhibitor against human AML cells.

Regulation of STAT3 by histone deacetylase-3 in diffuse large B-cell lymphoma: implications for therapy.

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