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Deoxycytidine-kinase knockdown as a novel myeloprotective strategy in the context of fludarabine, cytarabine or cladribine therapy.

  • Authors : Lachmann N; Reprogramming and Gene Therapy Group, REBIRTH Cluster of Excellence, Hannover Medical School, Hannover, Germany.; Institute of Experimental Hematology, Hannover Medical School, Hannover, Germany.

Subjects: Genetic Therapy*; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*adverse effects ; Bone Marrow/Bone Marrow/Bone Marrow/*drug effects

  • Source: Leukemia [Leukemia] 2015 Nov; Vol. 29 (11), pp. 2266-9. Date of Electronic Publication: 2015 Apr 29.Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Efficacy of cyclin-dependent-kinase 9 inhibitors in a murine model of mixed-lineage leukemia.

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Cyclin-Dependent Kinase 9/Cyclin-Dependent Kinase 9/Cyclin-Dependent Kinase 9/*antagonists & inhibitors ; Cyclin-Dependent Kinase 9/Cyclin-Dependent Kinase 9/Cyclin-Dependent Kinase 9/*metabolism

  • Source: Leukemia [Leukemia] 2014 Jul; Vol. 28 (7), pp. 1427-35. Date of Electronic Publication: 2014 Jan 21.Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium:

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Editorial & Opinion

Inherited susceptibility to pre B-ALL caused by germline transmission of PAX5 c.547G>A.

  • Authors : Auer F; Department of Pediatric Oncology, Hematology and Clinical Immunology, Center for Child and Adolescent Health, Heinrich Heine University, Düsseldorf, Germany.; Rüschendorf F

Subjects: Genetic Predisposition to Disease*; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma/Precursor B-Cell Lymphoblastic Leukemia-Lymphoma/Precursor B-Cell Lymphoblastic Leukemia-Lymphoma/*genetics; Female

  • Source: Leukemia [Leukemia] 2014 May; Vol. 28 (5), pp. 1136-8. Date of Electronic Publication: 2013 Nov 29.Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Differential expression of miR-17~92 identifies BCL2 as a therapeutic target in BCR-ABL-positive B-lineage acute lymphoblastic leukemia.

  • Authors : Scherr M; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.; Elder A

Subjects: Fusion Proteins, bcr-abl/Fusion Proteins, bcr-abl/Fusion Proteins, bcr-abl/*genetics ; Leukemia, B-Cell/Leukemia, B-Cell/Leukemia, B-Cell/*therapy ; MicroRNAs/MicroRNAs/MicroRNAs/*genetics

  • Source: Leukemia [Leukemia] 2014 Mar; Vol. 28 (3), pp. 554-65. Date of Electronic Publication: 2013 Nov 27.Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium:

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Report

The clinical relevance of minor paroxysmal nocturnal hemoglobinuria clones in refractory cytopenia of childhood: a prospective study by EWOG-MDS.

  • Authors : Aalbers AM; 1] Department of Pediatric Oncology/Hematology, Sophia Children's Hospital-Erasmus University Medical Center, Rotterdam, The Netherlands [2] Department of Immunology, Erasmus MC, Erasmus University Medical Center, Rotterdam, The Netherlands.; van der Velden VH

Subjects: Hemoglobinuria, Paroxysmal/Hemoglobinuria, Paroxysmal/Hemoglobinuria, Paroxysmal/*physiopathology ; Pancytopenia/Pancytopenia/Pancytopenia/*complications; Adolescent

  • Source: Leukemia [Leukemia] 2014 Jan; Vol. 28 (1), pp. 189-92. Date of Electronic Publication: 2013 Jun 28.Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium:

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Report

Early morbidity and mortality in childhood acute lymphoblastic leukemia with very high white blood cell count.

  • Authors : Vaitkeviciene G; 1] Clinic of Children's Diseases, Faculty of Medicine, Vilnius University, Vilnius, Lithuania [2] Department for Paediatric and Adolescent Medicine, Juliane Marrie Centre, University Hospital Rigshospitalet, Copenhagen, Denmark.; Heyman M

Subjects: Leukocytosis/Leukocytosis/Leukocytosis/*blood ; Leukocytosis/Leukocytosis/Leukocytosis/*mortality ; Mortality/Mortality/Mortality/*trends

  • Source: Leukemia [Leukemia] 2013 Nov; Vol. 27 (11), pp. 2259-62. Date of Electronic Publication: 2013 May 02.Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Physicians compliance during maintenance therapy in children with Down syndrome and acute lymphoblastic leukemia.

Subjects: Guideline Adherence* ; Practice Patterns, Physicians'*; Down Syndrome/Down Syndrome/Down Syndrome/*complications

  • Source: Leukemia [Leukemia] 2013 Apr; Vol. 27 (4), pp. 866-70. Date of Electronic Publication: 2012 Nov 09.Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Loss-of-function mutations within the IL-2 inducible kinase ITK in patients with EBV-associated lymphoproliferative diseases.

  • Authors : Linka RM; Department of Pediatric Oncology, Hematology and Clinical Immunology, Centre for Child and Adolescent Health, Medical Faculty, Heinrich-Heine University, Dusseldorf, Germany.; Risse SL

Subjects: Germ-Line Mutation*; Herpesvirus 4, Human/Herpesvirus 4, Human/Herpesvirus 4, Human/*physiology ; Lymphoproliferative Disorders/Lymphoproliferative Disorders/Lymphoproliferative Disorders/*virology

  • Source: Leukemia [Leukemia] 2012 May; Vol. 26 (5), pp. 963-71. Date of Electronic Publication: 2012 Jan 06.Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Human but not murine multipotent mesenchymal stromal cells exhibit broad-spectrum antimicrobial effector function mediated by indoleamine 2,3-dioxygenase.

  • Authors : Meisel R; Clinic of Pediatric Oncology, Hematology and Clinical Immunology, Center for Child and Adolescent Health, Heinrich-Heine-University, Medical Faculty, Düsseldorf, Germany. ; Brockers S

Subjects: Anti-Bacterial Agents/Anti-Bacterial Agents/Anti-Bacterial Agents/*metabolism ; Bacteria/Bacteria/Bacteria/*growth & development ; Cytomegalovirus/Cytomegalovirus/Cytomegalovirus/*growth & development

  • Source: Leukemia [Leukemia] 2011 Apr; Vol. 25 (4), pp. 648-54. Date of Electronic Publication: 2011 Jan 18.Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Hematopoietic stem cell transplantation for advanced myelodysplastic syndrome in children: results of the EWOG-MDS 98 study.

Subjects: Hematopoietic Stem Cell Transplantation*/Hematopoietic Stem Cell Transplantation*/Hematopoietic Stem Cell Transplantation*/mortality; Myelodysplastic Syndromes/Myelodysplastic Syndromes/Myelodysplastic Syndromes/*surgery; Adolescent

  • Source: Leukemia [Leukemia] 2011 Mar; Vol. 25 (3), pp. 455-62. Date of Electronic Publication: 2011 Jan 07.Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium:

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