نتائج البحث

Gene expression analysis in circulating tumour cells to determine resistance to CDK4/6 inhibitors plus endocrine therapy in HR + /HER2- metastatic breast cancer patients.

• Authors : González-Conde, Miriam¹ (AUTHOR); Yáñez, Celso¹ (AUTHOR); Abuín, Carmen¹ (AUTHOR)

• Source: Journal of Translational Medicine. 4/4/2025, Vol. 23 Issue 1, p1-18. 18p.

تفاصيل العنوان

The effectiveness and safety of RC48 alone or in combination with PD-1 inhibitors for locally advanced or metastatic urothelial carcinoma: a multicenter, real-world study.

• Authors : Ge H; Department of Urology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.; Liu C

Subjects: Neoplasm Metastasis* ; Immune Checkpoint Inhibitors*/Immune Checkpoint Inhibitors*/Immune Checkpoint Inhibitors*/therapeutic use; Humans

• Source: Journal of translational medicine [J Transl Med] 2025 Feb 28; Vol. 23 (1), pp. 243. Date of Electronic Publication: 2025 Feb 28.Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876

تفاصيل العنوان

Link of TMPRSS2 expression with tumor immunogenicity and response to immune checkpoint inhibitors in cancers.

• Authors : Subbarayan K; Medical Faculty, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany.; Bieber H

Subjects: COVID-19*/COVID-19*/COVID-19*/immunology ; Neoplasms*/Neoplasms*/Neoplasms*/immunology ; Serine Endopeptidases*/Serine Endopeptidases*/Serine Endopeptidases*/metabolism

• Source: Journal of translational medicine [J Transl Med] 2025 Mar 07; Vol. 23 (1), pp. 294. Date of Electronic Publication: 2025 Mar 07.Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876

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Unveiling the benefits of Vitamin D3 with SGLT-2 inhibitors for hypertensive obese obstructive sleep apnea patients.

• Authors : Loh HH; Department of Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, 56000, Kuala Lumpur, Malaysia. .; Faculty of Medicine and Health Sciences, Universiti Malaysia Sarawak, 93350, Kota Samarahan, Sarawak, Malaysia. .

Subjects: Obesity*/Obesity*/Obesity*/complications ; Obesity*/Obesity*/Obesity*/drug therapy ; Sleep Apnea, Obstructive*/Sleep Apnea, Obstructive*/Sleep Apnea, Obstructive*/drug therapy

• Source: Journal of translational medicine [J Transl Med] 2025 Mar 07; Vol. 23 (1), pp. 296. Date of Electronic Publication: 2025 Mar 07.Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876

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Application of PARP inhibitors combined with immune checkpoint inhibitors in ovarian cancer.

• Authors : Xiao, Fen^1,2 (AUTHOR); Wang, ZhiBin² (AUTHOR); Qiao, Liu^1,2 (AUTHOR)

• Source: Journal of Translational Medicine. 8/21/2024, Vol. 22 Issue 1, p1-17. 17p.

تفاصيل العنوان

Single-cell and spatial transcriptomics reveal SPP1-CD44 signaling drives primary resistance to immune checkpoint inhibitors in RCC.

• Authors : Zhang J; Department of Urology, Xinjiang Medical University Affiliated Cancer Hospital, Urumqi, China.; Peng Q

Subjects: Carcinoma, Renal Cell*/Carcinoma, Renal Cell*/Carcinoma, Renal Cell*/drug therapy ; Carcinoma, Renal Cell*/Carcinoma, Renal Cell*/Carcinoma, Renal Cell*/genetics ; Carcinoma, Renal Cell*/Carcinoma, Renal Cell*/Carcinoma, Renal Cell*/immunology

• Source: Journal of translational medicine [J Transl Med] 2024 Dec 30; Vol. 22 (1), pp. 1157. Date of Electronic Publication: 2024 Dec 30.Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876

تفاصيل العنوان

Discovery of novel VEGFR2 inhibitors against non-small cell lung cancer based on fingerprint-enhanced graph attention convolutional network.

• Authors : Wang Z; Department of Pharmacy, Honghui Hospital, Xi'an Jiaotong University, Xi'an, 710054, China. .; Sun L

Subjects: Vascular Endothelial Growth Factor Receptor-2*/Vascular Endothelial Growth Factor Receptor-2*/Vascular Endothelial Growth Factor Receptor-2*/antagonists & inhibitors ; Vascular Endothelial Growth Factor Receptor-2*/Vascular Endothelial Growth Factor Receptor-2*/Vascular Endothelial Growth Factor Receptor-2*/metabolism ; Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/drug therapy

• Source: Journal of translational medicine [J Transl Med] 2024 Dec 03; Vol. 22 (1), pp. 1097. Date of Electronic Publication: 2024 Dec 03.Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876

تفاصيل العنوان

Local delivery of accutox® synergises with immune-checkpoint inhibitors at disrupting tumor growth.

• Authors : Bikorimana, Jean Pierre¹ (AUTHOR); El-Hachem, Nehme^2,3 (AUTHOR); Abusarah, Jamilah⁴ (AUTHOR)

• Source: Journal of Translational Medicine. 6/3/2024, Vol. 22 Issue 1, p1-16. 16p.

تفاصيل العنوان

Immune checkpoint inhibitors induce acute interstitial nephritis in mice with increased urinary MCP1 and PD-1 glomerular expression.

• Authors : Martinez Valenzuela, Laura¹ (AUTHOR) ; Gómez-Preciado, Francisco¹ (AUTHOR); Guiteras, Jordi^2,3 (AUTHOR)

• Source: Journal of Translational Medicine. 5/3/2024, Vol. 22 Issue 1, p1-12. 12p.

تفاصيل العنوان

Clinical trial landscape for histone deacetylation inhibitors in breast cancer: a dawn in the darkness?

• Authors : Li, Jiajun¹ (AUTHOR); Yan, Yining¹ (AUTHOR); Chen, Feng¹ (AUTHOR)

• Source: Journal of Translational Medicine. 11/28/2024, Vol. 22 Issue 1, p1-3. 3p.

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