نتائج البحث

Pyruvate kinase M2 modulates mitochondrial dynamics and EMT in alveolar epithelial cells during sepsis-associated pulmonary fibrosis.

• Authors : Feng J; Department of Critical Care Medicine, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Key Laboratory of Anesthesiology, Shanghai Jiao Tong University, Ministry of Education, Shanghai, China.

Subjects: Epithelial-Mesenchymal Transition*/Epithelial-Mesenchymal Transition*/Epithelial-Mesenchymal Transition*/drug effects ; Mitochondrial Dynamics*/Mitochondrial Dynamics*/Mitochondrial Dynamics*/drug effects ; Pulmonary Fibrosis*/Pulmonary Fibrosis*/Pulmonary Fibrosis*/pathology

• Source: Journal of translational medicine [J Transl Med] 2025 Feb 19; Vol. 23 (1), pp. 205. Date of Electronic Publication: 2025 Feb 19.Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876

تفاصيل العنوان

Multi-omic studies on the pathogenesis of Sepsis.

• Authors : Tong H; Department of Critical Care Medicine, Jinhua Hospital Affiliated to Zhejiang University, Jinhua, Zhejiang, China.; Zhejiang University School of Medicine, Hangzhou, China.

Subjects: Sepsis*/Sepsis*/Sepsis*/genetics ; Mendelian Randomization Analysis*; Humans

• Source: Journal of translational medicine [J Transl Med] 2025 Mar 24; Vol. 23 (1), pp. 361. Date of Electronic Publication: 2025 Mar 24.Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876

تفاصيل العنوان

Micheliolide attenuates sepsis-induced acute lung injury by suppressing mitochondrial oxidative stress and PFKFB3-driven glycolysis.

• Authors : Li W; Department of Respiratory and Critical Care Medicine, Nanfang Hospital, Southern Medical University, 1838 Guangzhou North Road, Guangzhou, 510515, China.; Li Y

Subjects: Glycolysis*/Glycolysis*/Glycolysis*/drug effects ; Sepsis*/Sepsis*/Sepsis*/complications ; Sepsis*/Sepsis*/Sepsis*/drug therapy

• Source: Journal of translational medicine [J Transl Med] 2025 Feb 14; Vol. 23 (1), pp. 181. Date of Electronic Publication: 2025 Feb 14.Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876

تفاصيل العنوان

Exosomes as novel biomarkers in sepsis and sepsis related organ failure.

• Authors : Yuan Y; Department of Burns and Cutaneous Surgery, Xijing Hospital, Fourth Military Medical University, Chang-Le Xi Street #127, Xi'an, 710032, China.; Xiao Y

Subjects: Sepsis*/Sepsis*/Sepsis*/diagnosis ; Sepsis*/Sepsis*/Sepsis*/blood ; Biomarkers*/Biomarkers*/Biomarkers*/metabolism

• Source: Journal of translational medicine [J Transl Med] 2024 Nov 28; Vol. 22 (1), pp. 1078. Date of Electronic Publication: 2024 Nov 28.Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876

تفاصيل العنوان

Developing a rapid screening tool for high-risk ICU patients of sepsis: integrating electronic medical records with machine learning methods for mortality prediction in hospitalized patients-model establishment, internal and external validation, and visualization.

• Authors : Shi S; Department of Critical Care Medicine, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital South Branch, Fujian Provincial Hospital, Fuzhou University Affiliated Provincial Hospital, Fuzhou, 350001, People's Republic of China.; Zhang L

Subjects: Sepsis*/Sepsis*/Sepsis*/mortality ; Sepsis*/Sepsis*/Sepsis*/diagnosis ; Machine Learning*

• Source: Journal of translational medicine [J Transl Med] 2025 Jan 21; Vol. 23 (1), pp. 97. Date of Electronic Publication: 2025 Jan 21.Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876

تفاصيل العنوان

LIN28A-dependent lncRNA NEAT1 aggravates sepsis-induced acute respiratory distress syndrome through destabilizing ACE2 mRNA by RNA methylation.

• Authors : Liu J; Department of Anesthesiology, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510630, China.; Li X

Subjects: RNA, Long Noncoding*/RNA, Long Noncoding*/RNA, Long Noncoding*/genetics ; RNA, Long Noncoding*/RNA, Long Noncoding*/RNA, Long Noncoding*/metabolism ; Sepsis*/Sepsis*/Sepsis*/complications

• Source: Journal of translational medicine [J Transl Med] 2025 Jan 06; Vol. 23 (1), pp. 15. Date of Electronic Publication: 2025 Jan 06.Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876

تفاصيل العنوان

Parthenolide improves sepsis-induced coagulopathy by inhibiting mitochondrial-mediated apoptosis in vascular endothelial cells through BRD4/BCL-xL pathway

• Authors : Jun Zhang; Xing Zhu; Yong Li

Subjects: Sepsis-induced coagulopathy; Vascular endothelial cells; Parthenolide

• Source: Journal of Translational Medicine, Vol 23, Iss 1, Pp 1-16 (2025)

تفاصيل العنوان

Construction and validation of prognostic models in critically Ill patients with sepsis-associated acute kidney injury: interpretable machine learning approach.

• Authors : Fan, Zhiyan¹ (AUTHOR); Jiang, Jiamei² (AUTHOR); Xiao, Chen¹ (AUTHOR)

• Source: Journal of Translational Medicine. 6/22/2023, Vol. 21 Issue 1, p1-15. 15p.

تفاصيل العنوان

Propofol improves survival in a murine model of sepsis via inhibiting Rab5a-mediated intracellular trafficking of TLR4.

• Authors : Zhou BW; Department of Anesthesiology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, People's Republic of China.; Zhang WJ

Subjects: Propofol*/Propofol*/Propofol*/pharmacology ; Propofol*/Propofol*/Propofol*/therapeutic use ; Propofol*/Propofol*/Propofol*/metabolism

• Source: Journal of translational medicine [J Transl Med] 2024 Mar 28; Vol. 22 (1), pp. 316. Date of Electronic Publication: 2024 Mar 28.Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876

تفاصيل العنوان

Causal effects of gut microbiota on sepsis and sepsis-related death: insights from genome-wide Mendelian randomization, single-cell RNA, bulk RNA sequencing, and network pharmacology.

• Authors : Yang, Sha¹ (AUTHOR); Guo, Jing¹ (AUTHOR); Kong, Zhuo² (AUTHOR)

• Source: Journal of Translational Medicine. 1/2/2024, Vol. 22 Issue 1, p1-22. 22p.

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