نتائج البحث

Implementation of Nanopore sequencing as a pragmatic workflow for copy number variant confirmation in the clinic.

• Authors : Greer, Stephanie U.¹ (AUTHOR); Botello, Jacquelin¹ (AUTHOR); Hongo, Donna¹ (AUTHOR)

• Source: Journal of Translational Medicine. 6/10/2023, Vol. 21 Issue 1, p1-11. 11p.

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Droplet digital PCR allows vector copy number assessment and monitoring of experimental CAR T cells in murine xenograft models or approved CD19 CAR T cell-treated patients.

• Authors : Haderbache, Rafik; Warda, Walid; Hervouet, Eric

Subjects: Axi-cel; Chimeric antigen receptor; Droplet digital PCR

• Source: Journal of Translational Medicine. 19(1)

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High level of aneuploidy and recurrent loss of chromosome 11 as relevant features of somatotroph pituitary tumors.

• Authors : Rymuza, Julia¹ (AUTHOR); Kober, Paulina¹ (AUTHOR); Maksymowicz, Maria² (AUTHOR)

• Source: Journal of Translational Medicine. 11/6/2024, Vol. 22 Issue 1, p1-19. 19p.

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CNV-mediated dysregulation of the ceRNA network mechanism revealed heterogeneity in diffuse and intestinal gastric cancers.

• Authors : Xu R; College of Bioinformatics Science and Technology, Harbin Medical University, Harbin, 150081, China.; He D

Subjects: Stomach Neoplasms*/Stomach Neoplasms*/Stomach Neoplasms*/genetics ; Stomach Neoplasms*/Stomach Neoplasms*/Stomach Neoplasms*/pathology ; DNA Copy Number Variations*/DNA Copy Number Variations*/DNA Copy Number Variations*/genetics

• Source: Journal of translational medicine [J Transl Med] 2025 Mar 11; Vol. 23 (1), pp. 308. Date of Electronic Publication: 2025 Mar 11.Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876

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Low mitochondrial DNA copy number induces chemotherapy resistance via epithelial-mesenchymal transition by DNA methylation in esophageal squamous cancer cells

• Authors : Yuto Kubo; Koji Tanaka; Yasunori Masuike

Subjects: DNA methylation; Epithelial-Mesenchymal Transition; DNA Copy Number Variations

• Source: J Transl MedJournal of Translational Medicine, Vol 20, Iss 1, Pp 1-21 (2022)

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Eight-lncRNA signature of cervical cancer were identified by integrating DNA methylation, copy number variation and transcriptome data

• Authors : Qihang Zhong; Minzhen Lu; Wanqiong Yuan

Subjects: Copy number variation; Multi-omics integration analysis; lncRNA signature

• Source: Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-16 (2021)

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High copy number variations, particular transcription factors, and low immunity contribute to the stemness of prostate cancer cells.

• Authors : Dai Z; College of Life Sciences, Nanjing Normal University, Nanjing, Jiangsu, China.; Liu P

Subjects: DNA Copy Number Variations*/DNA Copy Number Variations*/DNA Copy Number Variations*/genetics ; Prostatic Neoplasms*/Prostatic Neoplasms*/Prostatic Neoplasms*/genetics; Gene Expression Profiling

• Source: Journal of translational medicine [J Transl Med] 2021 May 13; Vol. 19 (1), pp. 206. Date of Electronic Publication: 2021 May 13.Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876

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Application of droplet digital PCR for the detection of vector copy number in clinical CAR/TCR T cell products

• Authors : Alex Lu; Hui Liu; Rongye Shi

Subjects: Droplet digital PCR; Vector copy number; Genetically engineered T cells

• Source: Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-7 (2020)

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High positive predictive value of CNVs detected by clinical exome sequencing in suspected genetic diseases.

• Authors : Zeng Y; Medical Genetics Center, Guangdong Women and Children Hospital, Xingnan Road 521, Guangzhou, 510010, Guangdong, China.; Maternal and Children Metabolic-Genetic Key Laboratory, Guangdong Women and Children Hospital, Guangzhou, China.

Subjects: DNA Copy Number Variations*/DNA Copy Number Variations*/DNA Copy Number Variations*/genetics ; Exome Sequencing* ; Genetic Diseases, Inborn*/Genetic Diseases, Inborn*/Genetic Diseases, Inborn*/diagnosis

• Source: Journal of translational medicine [J Transl Med] 2024 Jul 09; Vol. 22 (1), pp. 644. Date of Electronic Publication: 2024 Jul 09.Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876

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Identification of prognostic values defined by copy number variation, mRNA and protein expression of LANCL2 and EGFR in glioblastoma patients

• Authors : Yan-wen Xu; Zong-yang Li; Wenlan Liu

Subjects: 0301 basic medicine; DNA Copy Number Variations; Overexpression

• Source: J Transl MedJournal of Translational Medicine, Vol 19, Iss 1, Pp 1-15 (2021)

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