Source: Journal of pharmaceutical sciences [J Pharm Sci] 2011 Jul; Vol. 100 (7), pp. 2526-42. Date of Electronic Publication: 2011 Jan 25.Publisher: Elsevier Country of Publication: United States NLM ID: 2985195R Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Solution behavior of a novel type 1 interferon, interferon-tau.

Authors : Katayama DS; Center for Pharmaceutical Biotechnology, University of Colorado Health Sciences Center, Denver, Colorado, USA.; Nayar R

Subjects: Antiviral Agents/Antiviral Agents/Antiviral Agents/*chemistry ; Interferon Type I/Interferon Type I/Interferon Type I/*chemistry ; Pregnancy Proteins/Pregnancy Proteins/Pregnancy Proteins/*chemistry

Source: Journal of pharmaceutical sciences [J Pharm Sci] 2005 Dec; Vol. 94 (12), pp. 2703-15.Publisher: Elsevier Country of Publication: United States NLM ID: 2985195R Publication Model: Print Cited Medium: Print ISSN: 0022-3549 (Print)

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Academic Journal

Biophysical characterization of insoluble aggregates of a multi-domain protein: an insight into the role of the various domains.

Authors : Souillac PO; Pharmaceutical Sciences and Technology group, Biogen Idec, 14 Cambridge Center, Cambridge, Massachusetts 02142, USA.

Subjects: Glycoproteins/Glycoproteins/Glycoproteins/*chemistry ; Immunoglobulin G/Immunoglobulin G/Immunoglobulin G/*chemistry ; Recombinant Fusion Proteins/Recombinant Fusion Proteins/Recombinant Fusion Proteins/*chemistry

Source: Journal of pharmaceutical sciences [J Pharm Sci] 2005 Sep; Vol. 94 (9), pp. 2069-83.Publisher: Elsevier Country of Publication: United States NLM ID: 2985195R Publication Model: Print Cited Medium: Print ISSN: 0022-3549 (Print)

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Academic Journal

Zanamivir Amidoxime- and N-Hydroxyguanidine-Based Prodrug Approaches to Tackle Poor Oral Bioavailability.

Authors : Schade, Dennis¹; Kotthaus, Jürke¹; Riebling, Lukas¹

Subjects: *RELENZA (Drug); *GUANIDINES; *NEURAMINIDASE

Source: Journal of Pharmaceutical Sciences. Sep2015, Vol. 104 Issue 9, p3208-3219. 12p. 1 Color Photograph, 1 Black and White Photograph, 1 Diagram, 4 Charts, 2

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Academic Journal

Application of a High-Throughput Relative Chemical Stability Assay to Screen Therapeutic Protein Formulations by Assessment of Conformational Stability and Correlation to Aggregation Propensity.

Authors : Rizzo, Joseph M.¹; Shi, Shuai¹; Li, Yunsong¹

Subjects: *CHEMICAL stability; *THERAPEUTIC use of proteins; *CONFORMATIONAL analysis

Source: Journal of Pharmaceutical Sciences. May2015, Vol. 104 Issue 5, p1632-1640. 9p. 3 Charts, 7 Graphs.

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Biophysical Characterization of Insoluble Aggregates of a Multi-Domain Protein: An Insight into the Role of the Various Domains

Authors : Pierre O. Souillac

Subjects: Protein Denaturation; Protein Folding; Protein Conformation

Source: Journal of Pharmaceutical Sciences. 94:2069-2083

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Metal-Leachate-Induced Conjugate Protein Instability

Authors : Ning Li; Wei Wang; Satish K. Singh

Subjects: Protein Denaturation; Vaccines; Protein Stability

Source: Journal of Pharmaceutical Sciences. 101:2733-2743

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Evaluation of a Non-Arrhenius Model for Therapeutic Monoclonal Antibody Aggregation

Authors : Bernhardt L. Trout; Bernhard Helk; Naresh Chennamsetty

Subjects: Protein Folding; Light; Protein Conformation

Source: Journal of Pharmaceutical Sciences. 100:2526-2542

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Solution behavior of a novel type 1 interferon, interferon-τ

Authors : Lorelie Villarete; Danny K. Chou; Jackie Campos

Subjects: Protein Folding; Molecular Sequence Data; Pharmaceutical Science

Source: Journal of Pharmaceutical Sciences. 94:2703-2715

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نتائج البحث

فلترة النتائج

Nonnative aggregation of an IgG1 antibody in acidic conditions: Part 1. Unfolding, colloidal interactions, and formation of high-molecular-weight aggregates.

Evaluation of a non-Arrhenius model for therapeutic monoclonal antibody aggregation.

Solution behavior of a novel type 1 interferon, interferon-tau.

Biophysical characterization of insoluble aggregates of a multi-domain protein: an insight into the role of the various domains.

Zanamivir Amidoxime- and N-Hydroxyguanidine-Based Prodrug Approaches to Tackle Poor Oral Bioavailability.

Application of a High-Throughput Relative Chemical Stability Assay to Screen Therapeutic Protein Formulations by Assessment of Conformational Stability and Correlation to Aggregation Propensity.

Biophysical Characterization of Insoluble Aggregates of a Multi-Domain Protein: An Insight into the Role of the Various Domains

Metal-Leachate-Induced Conjugate Protein Instability

Evaluation of a Non-Arrhenius Model for Therapeutic Monoclonal Antibody Aggregation

Solution behavior of a novel type 1 interferon, interferon-τ

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