Item request has been placed! ×
Item request cannot be made. ×
loading  Processing Request
Item request has been placed! ×
Item request cannot be made. ×
loading  Processing Request
Academic Journal

Targeting the NLRP3 inflammasome in cochlear macrophages protects against hearing loss in chronic suppurative otitis media.

  • Authors : Schiel V; Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Stanford University, Palo Alto, CA, 94305, USA.; Bhattacharya R

Subjects: Cochlea*/Cochlea*/Cochlea*/metabolism ; Cochlea*/Cochlea*/Cochlea*/pathology ; Inflammasomes*/Inflammasomes*/Inflammasomes*/metabolism

  • Source: Journal of neuroinflammation [J Neuroinflammation] 2024 Sep 14; Vol. 21 (1), pp. 223. Date of Electronic Publication: 2024 Sep 14.Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094

تفاصيل العنوان

×
Academic Journal

NLRP3 ablation enhances tolerance in heat stroke pathology by inhibiting IL-1β-mediated neuroinflammation.

  • Authors : Zhang ZT; Department of Hepato-Biliary Surgery, Shenzhen Third People's Hospital, The Second Affiliated Hospital, Southern University of Science and Technology, No.29 Bulan Road, Longgang District, Shenzhen, 518055, China.; Gu XL

Subjects: Brain/Brain/Brain/*metabolism ; Brain/Brain/Brain/*pathology ; Heat Stroke/Heat Stroke/Heat Stroke/*complications

  • Source: Journal of neuroinflammation [J Neuroinflammation] 2021 Jun 06; Vol. 18 (1), pp. 128. Date of Electronic Publication: 2021 Jun 06.Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094

تفاصيل العنوان

×
Academic Journal

An allosteric interleukin-1 receptor modulator mitigates inflammation and photoreceptor toxicity in a model of retinal degeneration.

  • Authors : Dabouz R; Department of Pharmacology and Therapeutics, McGill University, Montreal, QC, Canada.; Departments of Pediatrics, Ophthalmology, and Pharmacology, Hôpital Maisonneuve-Rosemont Research Center, 5415 Boul L'Assomption, Montreal, QC, H1T 2 M4, Canada.

Subjects: Interleukin-1beta/Interleukin-1beta/Interleukin-1beta/*immunology ; Peptides/Peptides/Peptides/*pharmacology ; Photoreceptor Cells/Photoreceptor Cells/Photoreceptor Cells/*pathology

  • Source: Journal of neuroinflammation [J Neuroinflammation] 2020 Nov 27; Vol. 17 (1), pp. 359. Date of Electronic Publication: 2020 Nov 27.Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094

تفاصيل العنوان

×
Academic Journal

IL-1β-driven amyloid plaque clearance is associated with an expansion of transcriptionally reprogrammed microglia.

  • Authors : Rivera-Escalera F; Department of Neuroscience, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Box 603, Rochester, NY, 14642, USA.; David H. Smith Center for Vaccine Biology and Immunology, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA.

Subjects: Cellular Reprogramming/Cellular Reprogramming/Cellular Reprogramming/*physiology ; Interleukin-1beta/Interleukin-1beta/Interleukin-1beta/*biosynthesis ; Microglia/Microglia/Microglia/*metabolism

  • Source: Journal of neuroinflammation [J Neuroinflammation] 2019 Dec 10; Vol. 16 (1), pp. 261. Date of Electronic Publication: 2019 Dec 10.Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094

تفاصيل العنوان

×
Academic Journal

Reactive microglia and IL1β/IL-1R1-signaling mediate neuroprotection in excitotoxin-damaged mouse retina.

  • Authors : Todd L; Department of Biological Structure, University of Washington, Seattle, WA, USA.; Palazzo I

Subjects: Interleukin-1beta/Interleukin-1beta/Interleukin-1beta/*metabolism ; Microglia/Microglia/Microglia/*metabolism ; Neuroprotection/Neuroprotection/Neuroprotection/*physiology

  • Source: Journal of neuroinflammation [J Neuroinflammation] 2019 Jun 06; Vol. 16 (1), pp. 118. Date of Electronic Publication: 2019 Jun 06.Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094

تفاصيل العنوان

×
Academic Journal

Microglial NLRP3 inflammasome activation mediates IL-1β release and contributes to central sensitization in a recurrent nitroglycerin-induced migraine model.

  • Authors : He W; Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, 1st You Yi Road, Yu Zhong District, Chongqing, 400016, People's Republic of China.; Long T

Subjects: Central Nervous System Sensitization/Central Nervous System Sensitization/Central Nervous System Sensitization/*physiology ; Heterocyclic Compounds, 4 or More Rings/Heterocyclic Compounds, 4 or More Rings/Heterocyclic Compounds, 4 or More Rings/*therapeutic use ; Interleukin-1beta/Interleukin-1beta/Interleukin-1beta/*metabolism

  • Source: Journal of neuroinflammation [J Neuroinflammation] 2019 Apr 10; Vol. 16 (1), pp. 78. Date of Electronic Publication: 2019 Apr 10.Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094

تفاصيل العنوان

×
Academic Journal

Interleukin-1beta and tumor necrosis factor-alpha are expressed by different subsets of microglia and macrophages after ischemic stroke in mice.

  • Authors : Clausen BH; Medical Biotechnology Center, University of Southern Denmark, Odense, Denmark. ; Lambertsen KL

Subjects: Brain Ischemia/Brain Ischemia/Brain Ischemia/*immunology ; Encephalitis/Encephalitis/Encephalitis/*immunology ; Interleukin-1beta/Interleukin-1beta/Interleukin-1beta/*metabolism

  • Source: Journal of neuroinflammation [J Neuroinflammation] 2008 Oct 23; Vol. 5, pp. 46. Date of Electronic Publication: 2008 Oct 23.Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094

تفاصيل العنوان

×
Academic Journal

HSP60 critically regulates endogenous IL-1β production in activated microglia by stimulating NLRP3 inflammasome pathway.

  • Authors : Swaroop S; National Brain Research Centre, Manesar, Haryana, 122052, India.; Mahadevan A

Subjects: Chaperonin 60/Chaperonin 60/Chaperonin 60/*pharmacology ; Gene Expression Regulation/Gene Expression Regulation/Gene Expression Regulation/*physiology ; Interleukin-1beta/Interleukin-1beta/Interleukin-1beta/*metabolism

  • Source: Journal of neuroinflammation [J Neuroinflammation] 2018 Jun 09; Vol. 15 (1), pp. 177. Date of Electronic Publication: 2018 Jun 09.Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094

تفاصيل العنوان

×
Academic Journal

Serum amyloid A primes microglia for ATP-dependent interleukin-1β release.

  • Authors : Facci L; Department of Pharmaceutical and Pharmacological Sciences, University of Padua, Largo 'E. Meneghetti' 2, 35131, Padua, Italy.; Barbierato M

Subjects: Adenosine Triphosphate/Adenosine Triphosphate/Adenosine Triphosphate/*pharmacology ; Interleukin-1beta/Interleukin-1beta/Interleukin-1beta/*metabolism ; Microglia/Microglia/Microglia/*drug effects

  • Source: Journal of neuroinflammation [J Neuroinflammation] 2018 May 26; Vol. 15 (1), pp. 164. Date of Electronic Publication: 2018 May 26.Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094

تفاصيل العنوان

×
Academic Journal

Glial interleukin-1β upregulates neuronal sodium channel 1.7 in trigeminal ganglion contributing to temporomandibular joint inflammatory hypernociception in rats.

  • Authors : Zhang P; Central Laboratory, Peking University School and Hospital of Stomatology, 22 Zhongguancun Avenue South, Haidian District, Beijing, 100081, China.; Department of Oral & Maxillofacial Surgery, Peking University School and Hospital of Stomatology, 22 Zhongguancun Avenue South, Haidian District, Beijing, 100081, China.

Subjects: Inflammation/Inflammation/Inflammation/*metabolism ; Interleukin-1beta/Interleukin-1beta/Interleukin-1beta/*metabolism ; NAV1.7 Voltage-Gated Sodium Channel/NAV1.7 Voltage-Gated Sodium Channel/NAV1.7 Voltage-Gated Sodium Channel/*metabolism

  • Source: Journal of neuroinflammation [J Neuroinflammation] 2018 Apr 20; Vol. 15 (1), pp. 117. Date of Electronic Publication: 2018 Apr 20.Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094

تفاصيل العنوان

×
  • 1-10 ل  283 نتائج ل ""Interleukin-1beta""