مكتبة

Item request has been placed!

Item request cannot be made.

Processing Request

Academic Journal

Targeting Alzheimer's Disease: Evaluating the Efficacy of C-1 Functionalized N-Aryl-Tetrahydroisoquinolines as Cholinergic Enzyme Inhibitors and Promising Therapeutic Candidates.

Authors : Jovanović D; Vinča Institute of Nuclear Sciences, National Institute of the Republic of Serbia, University of Belgrade, P.O. Box 522, 11000 Belgrade, Serbia.; Filipović A

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/drug therapy ; Tetrahydroisoquinolines*/Tetrahydroisoquinolines*/Tetrahydroisoquinolines*/pharmacology; Humans

Source: International journal of molecular sciences [Int J Mol Sci] 2024 Jan 14; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 14.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

تفاصيل العنوان

اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي

Academic Journal

The Role of Elacridar, a P-gp Inhibitor, in the Re-Sensitization of PAC-Resistant Ovarian Cancer Cell Lines to Cytotoxic Drugs in 2D and 3D Cell Culture Models.

Authors : Stasiak P; Institute of Biological Sciences, University of Zielona Góra, 65-417 Zielona Góra, Poland.; The Doctoral School of Exact and Technical Sciences, University of Zielona Góra, 65-417 Zielona Góra, Poland.

Subjects: Drug Resistance, Neoplasm*/Drug Resistance, Neoplasm*/Drug Resistance, Neoplasm*/drug effects ; Ovarian Neoplasms*/Ovarian Neoplasms*/Ovarian Neoplasms*/drug therapy ; Ovarian Neoplasms*/Ovarian Neoplasms*/Ovarian Neoplasms*/metabolism

Source: International journal of molecular sciences [Int J Mol Sci] 2025 Jan 28; Vol. 26 (3). Date of Electronic Publication: 2025 Jan 28.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

تفاصيل العنوان

اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي

Academic Journal

Enhanced Bioactivity of Quercetin-Tetrahydroisoquinoline Derivatives: Effect on Lipophilicity, Enzymes Inhibition, Antioxidant Potential, and Cytotoxicity.

Authors : Vučkovski M; Vinča Institute of Nuclear Sciences, National Institute of the Republic of Serbia, University of Belgrade, P.O. Box 522, 11000 Belgrade, Serbia.; Filipović A

Subjects: Antioxidants*/Antioxidants*/Antioxidants*/pharmacology ; Antioxidants*/Antioxidants*/Antioxidants*/chemistry ; Quercetin*/Quercetin*/Quercetin*/pharmacology

Source: International journal of molecular sciences [Int J Mol Sci] 2024 Dec 05; Vol. 25 (23). Date of Electronic Publication: 2024 Dec 05.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

تفاصيل العنوان

اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي

Electronic Resource

Targeting Alzheimer’s Disease: Evaluating the Efficacy of C-1 Functionalized N-Aryl-Tetrahydroisoquinolines as Cholinergic Enzyme Inhibitors and Promising Therapeutic Candidates

Authors : Jovanović, Dunja; Filipović, Ana; Janjić, Goran

Subjects: tetrahydroisoquinolines; acetylcholinesterase; butyrylcholinesterase

Source: International Journal of Molecular Sciences

تفاصيل العنوان

اقرأ أكثر حفظ في قائمتي

Academic Journal

In-Silico Identification of Novel Pharmacological Synergisms: The Trabectedin Case.

Authors : Mannarino L; Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, 20072 Milan, Italy.; Laboratory of Cancer Pharmacology, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, 20089 Milan, Italy.

Subjects: Tetrahydroisoquinolines*/Tetrahydroisoquinolines*/Tetrahydroisoquinolines*/pharmacology ; Antineoplastic Agents*; Trabectedin/Trabectedin/Trabectedin/pharmacology

Source: International journal of molecular sciences [Int J Mol Sci] 2024 Feb 08; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 08.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

تفاصيل العنوان

اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي

Academic Journal

Blood-Brain Barrier Disruption Increases Amyloid-Related Pathology in TgSwDI Mice.

Authors : Abdallah IM; Department of Drug Discovery and Development, Harrison School of Pharmacy, Auburn University, 720 S Donahue Drive, Auburn, AL 36849, USA.; Al-Shami KM

Subjects: ATP Binding Cassette Transporter, Subfamily B, Member 1/ATP Binding Cassette Transporter, Subfamily B, Member 1/ATP Binding Cassette Transporter, Subfamily B, Member 1/*metabolism ; ATP Binding Cassette Transporter, Subfamily G, Member 2/ATP Binding Cassette Transporter, Subfamily G, Member 2/ATP Binding Cassette Transporter, Subfamily G, Member 2/*metabolism ; Acridines/Acridines/Acridines/*pharmacology

Source: International journal of molecular sciences [Int J Mol Sci] 2021 Jan 27; Vol. 22 (3). Date of Electronic Publication: 2021 Jan 27.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

تفاصيل العنوان

اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي

Academic Journal

Green Routes for the Production of Enantiopure Benzylisoquinoline Alkaloids.

Authors : Ghirga F; Center for Life Nano , Istituto Italiano di Tecnologia, Viale Regina Elena 291, 00161 Rome, Italy. .; Bonamore A

Subjects: Bioreactors*; Alkaloids/Alkaloids/Alkaloids/*chemical synthesis ; Benzylisoquinolines/Benzylisoquinolines/Benzylisoquinolines/*chemical synthesis

Source: International journal of molecular sciences [Int J Mol Sci] 2017 Nov 20; Vol. 18 (11). Date of Electronic Publication: 2017 Nov 20.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

تفاصيل العنوان

اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي

Academic Journal

Inhibition of the IgE-mediated activation of RBL-2H3 cells by TIPP, a novel thymic immunosuppressive pentapeptide.

Authors : Lian Q; Key Laboratory of Chemical Biology of Natural Products (Ministry of Education), Institute of Biochemical and Biotechnological Drugs, School of Pharmaceutical Sciences, Shandong University, Jinan 250012, China. .; Cheng Y

Subjects: Immunoglobulin E/Immunoglobulin E/Immunoglobulin E/*metabolism ; Immunosuppressive Agents/Immunosuppressive Agents/Immunosuppressive Agents/*pharmacology ; Mast Cells/Mast Cells/Mast Cells/*metabolism

Source: International journal of molecular sciences [Int J Mol Sci] 2015 Jan 20; Vol. 16 (1), pp. 2252-68. Date of Electronic Publication: 2015 Jan 20.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

تفاصيل العنوان

اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي

Academic Journal

Design, Radiosynthesis and Preliminary Biological Evaluation in Mice of a Brain-Penetrant 18 F-Labelled σ 2 Receptor Ligand.

Authors : Moldovan, Rareş-Petru¹ (AUTHOR) ; Gündel, Daniel¹ (AUTHOR) ; Teodoro, Rodrigo^1,2 (AUTHOR)

Subjects: *TETRAHYDROISOQUINOLINES; *POSITRON emission tomography; *MEMBRANE proteins

Source: International Journal of Molecular Sciences. Jun2021, Vol. 22 Issue 11, p5447. 1p.

تفاصيل العنوان

اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي

Academic Journal

Transcriptome Profile Analysis of Triple-Negative Breast Cancer Cells in Response to a Novel Cytostatic Tetrahydroisoquinoline Compared to Paclitaxel.

Authors : Gangapuram M; Pharmaceutical Sciences Division, College of Pharmacy & Pharmaceutical Sciences, Institute of Public Health, Florida A&M University, Tallahassee, FL 32307, USA.; Mazzio EA

Subjects: Benzamides/Benzamides/Benzamides/*pharmacology ; Cytostatic Agents/Cytostatic Agents/Cytostatic Agents/*pharmacology ; Isoquinolines/Isoquinolines/Isoquinolines/*pharmacology

Source: International journal of molecular sciences [Int J Mol Sci] 2021 Jul 19; Vol. 22 (14). Date of Electronic Publication: 2021 Jul 19.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

تفاصيل العنوان

اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي

نتائج البحث

فلترة النتائج

Targeting Alzheimer's Disease: Evaluating the Efficacy of C-1 Functionalized N-Aryl-Tetrahydroisoquinolines as Cholinergic Enzyme Inhibitors and Promising Therapeutic Candidates.

The Role of Elacridar, a P-gp Inhibitor, in the Re-Sensitization of PAC-Resistant Ovarian Cancer Cell Lines to Cytotoxic Drugs in 2D and 3D Cell Culture Models.

Enhanced Bioactivity of Quercetin-Tetrahydroisoquinoline Derivatives: Effect on Lipophilicity, Enzymes Inhibition, Antioxidant Potential, and Cytotoxicity.

Targeting Alzheimer’s Disease: Evaluating the Efficacy of C-1 Functionalized N-Aryl-Tetrahydroisoquinolines as Cholinergic Enzyme Inhibitors and Promising Therapeutic Candidates

In-Silico Identification of Novel Pharmacological Synergisms: The Trabectedin Case.

Blood-Brain Barrier Disruption Increases Amyloid-Related Pathology in TgSwDI Mice.

Green Routes for the Production of Enantiopure Benzylisoquinoline Alkaloids.

Inhibition of the IgE-mediated activation of RBL-2H3 cells by TIPP, a novel thymic immunosuppressive pentapeptide.

Design, Radiosynthesis and Preliminary Biological Evaluation in Mice of a Brain-Penetrant 18 F-Labelled σ 2 Receptor Ligand.

Transcriptome Profile Analysis of Triple-Negative Breast Cancer Cells in Response to a Novel Cytostatic Tetrahydroisoquinoline Compared to Paclitaxel.

اتصل بنا

اتبع