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Academic Journal

The Furin Protease Dependence and Antiviral GBP2 Sensitivity of Murine Leukemia Virus Infection Are Determined by the Amino Acid Sequence at the Envelope Glycoprotein Cleavage Site.

  • Authors : Kubo Y; Department of Clinical Medicine, Institute of Tropical Medicine, Nagasaki University, Nagasaki 852-8523, Japan.; Program for Nurturing Global Leaders in Tropical Medicine and Emerging Communicable Diseases, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki 852-8523, Japan.

Subjects: Furin*/Furin*/Furin*/metabolism ; Viral Envelope Proteins*/Viral Envelope Proteins*/Viral Envelope Proteins*/metabolism ; Viral Envelope Proteins*/Viral Envelope Proteins*/Viral Envelope Proteins*/genetics

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Sep 16; Vol. 25 (18). Date of Electronic Publication: 2024 Sep 16.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

The Role of Furin and Its Therapeutic Potential in Cardiovascular Disease Risk.

  • Authors : Fry H; Nuffield Department of Population Health, University of Oxford, Oxford OX3 7LF, UK.; Mazidi M

Subjects: Furin*/Furin*/Furin*/metabolism ; Furin*/Furin*/Furin*/genetics ; Cardiovascular Diseases*/Cardiovascular Diseases*/Cardiovascular Diseases*/metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Aug 26; Vol. 25 (17). Date of Electronic Publication: 2024 Aug 26.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Development and Prospects of Furin Inhibitors for Therapeutic Applications.

Subjects: Furin*/Furin*/Furin*/antagonists & inhibitors ; Furin*/Furin*/Furin*/metabolism; Humans

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Aug 24; Vol. 25 (17). Date of Electronic Publication: 2024 Aug 24.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Screening of Small-Molecule Libraries Using SARS-CoV-2-Derived Sequences Identifies Novel Furin Inhibitors.

  • Authors : Jorkesh A; Department of Pharmaceutical and Pharmacological Science, University of Padova, Via Marzolo, 5, 35131 Padova, Italy.; Department of Biology, University of Padua, Viale G. Colombo 3, 35131 Padova, Italy.

Subjects: Furin*/Furin*/Furin*/antagonists & inhibitors ; Furin*/Furin*/Furin*/metabolism ; SARS-CoV-2*/SARS-CoV-2*/SARS-CoV-2*/drug effects SARS-CoV-2 variants

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 May 07; Vol. 25 (10). Date of Electronic Publication: 2024 May 07.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Myelin Basic Protein Attenuates Furin-Mediated Bri2 Cleavage and Postpones Its Membrane Trafficking.

  • Authors : Smirnova EV; Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.; Timofeev VI

Subjects: Membrane Glycoproteins* ; Furin*/Furin*/Furin*/metabolism; Animals

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Feb 23; Vol. 25 (5). Date of Electronic Publication: 2024 Feb 23.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

SARS-CoV-2 S Mutations: A Lesson from the Viral World to Understand How Human Furin Works.

  • Authors : Cassari L; Department of Industrial Engineering, University of Padova, Via Marzolo 9, 35131 Padova, Italy.; Pavan A

Subjects: COVID-19* ; Furin*/Furin*/Furin*/metabolism ; SARS-CoV-2*/SARS-CoV-2*/SARS-CoV-2*/genetics

  • Source: International journal of molecular sciences [Int J Mol Sci] 2023 Mar 01; Vol. 24 (5). Date of Electronic Publication: 2023 Mar 01.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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