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Academic Journal

Pharmacomodulation of the Redox-Active Lead Plasmodione: Synthesis of Substituted 2-Benzylnaphthoquinone Derivatives, Antiplasmodial Activities, and Physicochemical Properties.

  • Authors : Presser A; Institute of Pharmaceutical Sciences, Pharmaceutical Chemistry, University of Graz, Schubertstrasse 1, 8010 Graz, Austria.; Blaser G

Subjects: Plasmodium falciparum*/Plasmodium falciparum*/Plasmodium falciparum*/drug effects ; Naphthoquinones*/Naphthoquinones*/Naphthoquinones*/pharmacology ; Naphthoquinones*/Naphthoquinones*/Naphthoquinones*/chemistry

  • Source: International journal of molecular sciences [Int J Mol Sci] 2025 Feb 27; Vol. 26 (5). Date of Electronic Publication: 2025 Feb 27.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Antiplasmodial Activity of a New Chemotype of Croton sylvaticus Hochst. Ex C. Krauss Essential Oil.

  • Authors : Taguimjeu PLKT; Laboratory of Chemistry of Natural Molecules, Gembloux Agro Bio-Tech, University of Liège, 5030 Gembloux, Belgium.; Department of Organic Chemistry, Faculty of Science, University of Yaoundé I, Yaoundé P.O. Box 812, Cameroon.

Subjects: Croton*/Croton*/Croton*/chemistry ; Oils, Volatile*/Oils, Volatile*/Oils, Volatile*/pharmacology ; Oils, Volatile*/Oils, Volatile*/Oils, Volatile*/chemistry

  • Source: International journal of molecular sciences [Int J Mol Sci] 2025 Jan 20; Vol. 26 (2). Date of Electronic Publication: 2025 Jan 20.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Identification of Malaria-Selective Proteasome β5 Inhibitors Through Pharmacophore Modeling, Molecular Docking, and Molecular Dynamics Simulation.

  • Authors : Yasir M; Department of Pharmacology, Kangwon National University School of Medicine, Chuncheon 24341, Republic of Korea.; Park J

Subjects: Molecular Dynamics Simulation* ; Molecular Docking Simulation* ; Antimalarials*/Antimalarials*/Antimalarials*/pharmacology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Nov 05; Vol. 25 (22). Date of Electronic Publication: 2024 Nov 05.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Mapping Antimalarial Drug Resistance in Mozambique: A Systematic Review of Plasmodium falciparum Genetic Markers Post-ACT Implementation.

  • Authors : Chaves CRS; Global Health and Tropical Medicine (GHTM), Associate Laboratory in Translation and Innovation Towards Global Health (LA-REAL), Instituto de Higiene e Medicina Tropical (IHMT), Universidade NOVA de Lisboa (UNL), Rua da Junqueira 100, 1349-008 Lisboa, Portugal.; da Silva C

Subjects: Antimalarials*/Antimalarials*/Antimalarials*/pharmacology ; Drug Resistance*/Drug Resistance*/Drug Resistance*/genetics ; Plasmodium falciparum*/Plasmodium falciparum*/Plasmodium falciparum*/drug effects

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Dec 20; Vol. 25 (24). Date of Electronic Publication: 2024 Dec 20.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Plasmodium falciparum Mitochondrial Complex III, the Target of Atovaquone, Is Essential for Progression to the Transmissible Sexual Stages.

  • Authors : Sheokand PK; Wellcome Centre for Integrative Parasitology, School of Infection and Immunity, University of Glasgow, Glasgow G12 8TA, UK.; Pradhan S

Subjects: Plasmodium falciparum*/Plasmodium falciparum*/Plasmodium falciparum*/drug effects ; Plasmodium falciparum*/Plasmodium falciparum*/Plasmodium falciparum*/growth & development ; Plasmodium falciparum*/Plasmodium falciparum*/Plasmodium falciparum*/metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Aug 26; Vol. 25 (17). Date of Electronic Publication: 2024 Aug 26.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Competitive Inhibition of Okanin against Plasmodium falciparum Tyrosyl-tRNA Synthetase.

  • Authors : Yang G; School of Public Health (Shenzhen), Shenzhen Campus of Sun Yat-sen University, Sun Yat-sen University, Shenzhen 518107, China.; Liang Y

Subjects: Plasmodium falciparum*/Plasmodium falciparum*/Plasmodium falciparum*/drug effects ; Plasmodium falciparum*/Plasmodium falciparum*/Plasmodium falciparum*/enzymology ; Tyrosine-tRNA Ligase*/Tyrosine-tRNA Ligase*/Tyrosine-tRNA Ligase*/antagonists & inhibitors

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Apr 26; Vol. 25 (9). Date of Electronic Publication: 2024 Apr 26.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Parallel Synthesis of Piperazine Tethered Thiazole Compounds with Antiplasmodial Activity.

  • Authors : Rayala R; Herbert Wertheim College of Medicine, Center for Translational Science, Florida International University, Miami, FL 33199, USA.; Chaudhari P

Subjects: Antimalarials*/Antimalarials*/Antimalarials*/chemistry; Piperazine ; Thiazoles/Thiazoles/Thiazoles/chemistry

  • Source: International journal of molecular sciences [Int J Mol Sci] 2023 Dec 12; Vol. 24 (24). Date of Electronic Publication: 2023 Dec 12.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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