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Academic Journal

Sequence dependencies and mutation rates of localized mutational processes in cancer.

  • Authors : Poulsgaard GA; Department of Clinical Medicine, Aarhus University, Palle Juul-Jensens Boulevard 82, 8200, Aarhus N, Denmark.; Department of Molecular Medicine (MOMA), Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200, Aarhus N, Denmark.

Subjects: Mutation Rate* ; Neoplasms*/Neoplasms*/Neoplasms*/genetics; Humans

  • Source: Genome medicine [Genome Med] 2023 Aug 17; Vol. 15 (1), pp. 63. Date of Electronic Publication: 2023 Aug 17.Publisher: BioMed Central Country of Publication: England NLM ID: 101475844 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-994X

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Academic Journal

Genetic variation in human drug-related genes.

  • Authors : Schärfe CPI; Department of Systems Biology, Harvard Medical School, Boston, 02115, Massachusetts, USA.; Center for Bioinformatics, University of Tübingen, 72076, Tübingen, Germany.

Subjects: Mutation Rate* ; Pharmacogenomic Variants*; Drug-Related Side Effects and Adverse Reactions/Drug-Related Side Effects and Adverse Reactions/Drug-Related Side Effects and Adverse Reactions/*genetics

  • Source: Genome medicine [Genome Med] 2017 Dec 22; Vol. 9 (1), pp. 117. Date of Electronic Publication: 2017 Dec 22.Publisher: BioMed Central Country of Publication: England NLM ID: 101475844 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-994X

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Academic Journal

Frequent mutations in acetylation and ubiquitination sites suggest novel driver mechanisms of cancer.

  • Authors : Narayan S; The Donnelly Centre, University of Toronto, Toronto, Canada.; Bader GD

Subjects: Mutation Rate* ; Protein Processing, Post-Translational*; Computational Biology/Computational Biology/Computational Biology/*methods

  • Source: Genome medicine [Genome Med] 2016 May 12; Vol. 8 (1), pp. 55. Date of Electronic Publication: 2016 May 12.Publisher: BioMed Central Country of Publication: England NLM ID: 101475844 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-994X

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Report

Exploring the implications of distinct mutational signatures and mutation rates in aging and cancer.

  • Authors : Fox EJ; Department of Pathology, University of Washington, Seattle, WA, 98195, USA. .; Salk JJ

Subjects: Genome, Human* ; Mutation* ; Mutation Rate*

  • Source: Genome medicine [Genome Med] 2016 Mar 17; Vol. 8 (1), pp. 30. Date of Electronic Publication: 2016 Mar 17.Publisher: BioMed Central Country of Publication: England NLM ID: 101475844 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-994X

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Academic Journal

Evolving neoantigen profiles in colorectal cancers with DNA repair defects.

  • Authors : Rospo G; Candiolo Cancer Institute, FPO-IRCCS, 10060, Candiolo (TO), Italy.; Lorenzato A

Subjects: Clonal Evolution* ; DNA Repair*; Antigens, Neoplasm/Antigens, Neoplasm/Antigens, Neoplasm/*genetics

  • Source: Genome medicine [Genome Med] 2019 Jun 28; Vol. 11 (1), pp. 42. Date of Electronic Publication: 2019 Jun 28.Publisher: BioMed Central Country of Publication: England NLM ID: 101475844 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-994X

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Academic Journal

Multi-omics discovery of exome-derived neoantigens in hepatocellular carcinoma.

Subjects: Transcriptome*; Antigens, Neoplasm/Antigens, Neoplasm/Antigens, Neoplasm/*genetics ; Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/*genetics

  • Source: Genome medicine [Genome Med] 2019 Apr 30; Vol. 11 (1), pp. 28. Date of Electronic Publication: 2019 Apr 30.Publisher: BioMed Central Country of Publication: England NLM ID: 101475844 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-994X

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Academic Journal

The impact of tumor profiling approaches and genomic data strategies for cancer precision medicine.

  • Authors : Garofalo A; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, 450 Brookline Avenue, Boston, MA, 02115, USA.; Broad Institute of MIT and Harvard, 7 Cambridge Center, Cambridge, MA, 02142, USA.

Subjects: Gene Expression Regulation, Neoplastic* ; Precision Medicine*; Adenocarcinoma/Adenocarcinoma/Adenocarcinoma/*genetics

  • Source: Genome medicine [Genome Med] 2016 Jul 26; Vol. 8 (1), pp. 79. Date of Electronic Publication: 2016 Jul 26.Publisher: BioMed Central Country of Publication: England NLM ID: 101475844 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-994X

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