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Academic Journal

Molecular features of untreated breast cancer and initial metastatic event inform clinical decision-making and predict outcome: long-term results of ESOPE, a single-arm prospective multicenter study.

Authors : Callens C; Genetics Department, Institut Curie, PSL Research University, Paris, France.; Driouch K

Subjects: Clinical Decision-Making*; Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*genetics ; Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*pathology

Source: Genome medicine [Genome Med] 2021 Mar 15; Vol. 13 (1), pp. 44. Date of Electronic Publication: 2021 Mar 15.Publisher: BioMed Central Country of Publication: England NLM ID: 101475844 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-994X

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Academic Journal

Molecular features of untreated breast cancer and initial metastatic event inform clinical decision-making and predict outcome: long-term results of ESOPE, a single-arm prospective multicenter study

Authors : Céline Callens; Keltouma Driouch; Anaïs Boulai

Subjects: Breast cancer; Metastasis; Next generation sequencing

Source: Genome Medicine, Vol 13, Iss 1, Pp 1-15 (2021)

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Molecular features of untreated breast cancer and initial metastatic event inform clinical decision-making and predict outcome: long-term results of ESOPE, a single-arm prospective multicenter study

Authors : Virginie Fourchotte; Céline Callens; Vincent Servois

Subjects: 0301 basic medicine; Oncology; lcsh:Medicine

Source: Genome Medicine, Vol 13, Iss 1, Pp 1-15 (2021)Genome Medicine

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Academic Journal

Patient and provider perspectives on polygenic risk scores: implications for clinical reporting and utilization.

Authors : Lewis ACF; E.J. Safra Center for Ethics, Harvard University, Cambridge, USA. .; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA. .

Subjects: Clinical Decision-Making* ; Primary Health Care*; Humans

Source: Genome medicine [Genome Med] 2022 Oct 07; Vol. 14 (1), pp. 114. Date of Electronic Publication: 2022 Oct 07.Publisher: BioMed Central Country of Publication: England NLM ID: 101475844 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-994X

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Academic Journal

Actionability of commercial laboratory sequencing panels for newborn screening and the importance of transparency for parental decision-making.

Authors : DeCristo DM; Department of Genetics, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, 27599, USA.; Milko LV

Subjects: Clinical Decision-Making* ; Clinical Laboratory Techniques* ; High-Throughput Nucleotide Sequencing*

Source: Genome medicine [Genome Med] 2021 Mar 29; Vol. 13 (1), pp. 50. Date of Electronic Publication: 2021 Mar 29.Publisher: BioMed Central Country of Publication: England NLM ID: 101475844 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-994X

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Academic Journal

Genome-wide sequencing as a first-tier screening test for short tandem repeat expansions.

Authors : Rajan-Babu IS; IMAGINE Study; CAUSES Study;

Subjects: DNA Repeat Expansion* ; Genome-Wide Association Study*/Genome-Wide Association Study*/Genome-Wide Association Study*/methods ; High-Throughput Nucleotide Sequencing*

Source: Genome medicine [Genome Med] 2021 Aug 09; Vol. 13 (1), pp. 126. Date of Electronic Publication: 2021 Aug 09.Publisher: BioMed Central Country of Publication: England NLM ID: 101475844 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-994X

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Academic Journal

Integrative statistical analyses of multiple liquid biopsy analytes in metastatic breast cancer.

Authors : Keup C; Department of Gynecology and Obstetrics, University Hospital of Essen, Hufelandstr. 55, 45122, Essen, Germany. .; Suryaprakash V

Subjects: Biomarkers, Tumor* ; Liquid Biopsy*/Liquid Biopsy*/Liquid Biopsy*/methods ; Liquid Biopsy*/Liquid Biopsy*/Liquid Biopsy*/standards

Source: Genome medicine [Genome Med] 2021 May 17; Vol. 13 (1), pp. 85. Date of Electronic Publication: 2021 May 17.Publisher: BioMed Central Country of Publication: England NLM ID: 101475844 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-994X

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Academic Journal

Genomics in the era of COVID-19: ethical implications for clinical practice and public health.

Authors : Geller G; Berman Institute of Bioethics, Johns Hopkins University, Deering Hall, Room 202, 1809 Ashland Ave., Baltimore, MD, 21205, USA. .; Johns Hopkins University School of Medicine, Baltimore, MD, USA. .

Subjects: Coronavirus Infections/Coronavirus Infections/Coronavirus Infections/*pathology ; Genetic Predisposition to Disease/Genetic Predisposition to Disease/Genetic Predisposition to Disease/*genetics ; Genetic Testing/Genetic Testing/Genetic Testing/*ethics

Source: Genome medicine [Genome Med] 2020 Nov 09; Vol. 12 (1), pp. 95. Date of Electronic Publication: 2020 Nov 09.Publisher: BioMed Central Country of Publication: England NLM ID: 101475844 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-994X

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Academic Journal

Best practices for variant calling in clinical sequencing.

Authors : Koboldt DC; Steve and Cindy Rasmussen Institute for Genomic Medicine at Nationwide Children's Hospital, Columbus, OH, USA. .; Department of Pediatrics, The Ohio State University, Columbus, OH, USA. .

Subjects: DNA Mutational Analysis*/DNA Mutational Analysis*/DNA Mutational Analysis*/methods ; DNA Mutational Analysis*/DNA Mutational Analysis*/DNA Mutational Analysis*/standards ; Genetic Testing*/Genetic Testing*/Genetic Testing*/methods

Source: Genome medicine [Genome Med] 2020 Oct 26; Vol. 12 (1), pp. 91. Date of Electronic Publication: 2020 Oct 26.Publisher: BioMed Central Country of Publication: England NLM ID: 101475844 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-994X

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Academic Journal

Personalized cancer therapy prioritization based on driver alteration co-occurrence patterns.

Authors : Mateo L; Joint IRB-BSC-CRG Program in Computational Biology, Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Catalonia, Spain.; Duran-Frigola M

Subjects: Models, Theoretical* ; Precision Medicine*/Precision Medicine*/Precision Medicine*/methods; Neoplasms/Neoplasms/Neoplasms/*etiology

Source: Genome medicine [Genome Med] 2020 Sep 09; Vol. 12 (1), pp. 78. Date of Electronic Publication: 2020 Sep 09.Publisher: BioMed Central Country of Publication: England NLM ID: 101475844 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-994X

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نتائج البحث

فلترة النتائج

Molecular features of untreated breast cancer and initial metastatic event inform clinical decision-making and predict outcome: long-term results of ESOPE, a single-arm prospective multicenter study.

Molecular features of untreated breast cancer and initial metastatic event inform clinical decision-making and predict outcome: long-term results of ESOPE, a single-arm prospective multicenter study

Molecular features of untreated breast cancer and initial metastatic event inform clinical decision-making and predict outcome: long-term results of ESOPE, a single-arm prospective multicenter study

Patient and provider perspectives on polygenic risk scores: implications for clinical reporting and utilization.

Actionability of commercial laboratory sequencing panels for newborn screening and the importance of transparency for parental decision-making.

Genome-wide sequencing as a first-tier screening test for short tandem repeat expansions.

Integrative statistical analyses of multiple liquid biopsy analytes in metastatic breast cancer.

Genomics in the era of COVID-19: ethical implications for clinical practice and public health.

Best practices for variant calling in clinical sequencing.

Personalized cancer therapy prioritization based on driver alteration co-occurrence patterns.

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