Authors : Zhang F; Cancer Institute, The Second Affiliated Hospital, Zhejiang University School of Medicine, 310009, Hangzhou, China.; Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, 310009, Hangzhou, China.

Subjects: Ubiquitin-Conjugating Enzymes*/Ubiquitin-Conjugating Enzymes*/Ubiquitin-Conjugating Enzymes*/metabolism ; Ubiquitin-Conjugating Enzymes*/Ubiquitin-Conjugating Enzymes*/Ubiquitin-Conjugating Enzymes*/genetics ; Mechanistic Target of Rapamycin Complex 1*/Mechanistic Target of Rapamycin Complex 1*/Mechanistic Target of Rapamycin Complex 1*/metabolism

Source: The EMBO journal [EMBO J] 2025 Feb; Vol. 44 (4), pp. 1185-1219. Date of Electronic Publication: 2025 Jan 06.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Functional conservation and divergence of the helix‐turn‐helix motif of E2 ubiquitin‐conjugating enzymes.

Authors : Welsh, Kaeli A¹ (AUTHOR); Bolhuis, Derek L² (AUTHOR); Nederstigt, Anneroos E³ (AUTHOR)

Subjects: *UBIQUITIN-conjugating enzymes; *HELIX-loop-helix motifs; *UBIQUITIN

Source: EMBO Journal. Feb2022, Vol. 41 Issue 3, p1-21. 21p.

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Academic Journal

Shared and distinct mechanisms of UBA1 inactivation across different diseases.

Authors : Collins, Jason C¹ (AUTHOR); Magaziner, Samuel J^2,3 (AUTHOR); English, Maya¹ (AUTHOR)

Subjects: *SPINAL muscular atrophy; *FRAGILE X syndrome; *UBIQUITINATION

Source: EMBO Journal. May2024, Vol. 43 Issue 10, p1919-1946. 28p.

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Structural basis for RAD18 regulation by MAGEA4 and its implications for RING ubiquitin ligase binding by MAGE family proteins.

Authors : Griffith-Jones S; European Molecular Biology Laboratory, 71 Avenue des Martyrs, 38042, Grenoble, France.; Álvarez L

Subjects: Ubiquitin-Conjugating Enzymes*/Ubiquitin-Conjugating Enzymes*/Ubiquitin-Conjugating Enzymes*/metabolism ; Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/genetics ; Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/metabolism

Source: The EMBO journal [EMBO J] 2024 Apr; Vol. 43 (7), pp. 1273-1300. Date of Electronic Publication: 2024 Mar 06.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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The SMC5/6 complex recruits the PAF1 complex to facilitate DNA double‐strand break repair in Arabidopsis.

Authors : Li, Cunliang^1,2,3,4,5 (AUTHOR); Guo, Yuyu^1,2,3,4,5 (AUTHOR); Wang, Lili^1,2,3,4,5 (AUTHOR)

Subjects: *DOUBLE-strand DNA breaks; *DNA repair; *UBIQUITIN ligases

Source: EMBO Journal. 4/3/2023, Vol. 42 Issue 7, p1-15. 15p.

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The UBA domain of conjugating enzyme Ubc1/Ube2K facilitates assembly of K48/K63‐branched ubiquitin chains.

Authors : Pluska, Lukas¹ (AUTHOR); Jarosch, Ernst¹ (AUTHOR); Zauber, Henrik¹ (AUTHOR)

Subjects: *UBIQUITIN; *UBIQUITIN-conjugating enzymes; *ENZYMES

Source: EMBO Journal. Mar2021, Vol. 40 Issue 6, p1-19. 19p.

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A non‐canonical scaffold‐type E3 ligase complex mediates protein UFMylation.

Authors : Peter, Joshua J¹ (AUTHOR); Magnussen, Helge M¹ (AUTHOR); DaRosa, Paul A² (AUTHOR)

Subjects: *UBIQUITIN ligases; *UBIQUITIN-conjugating enzymes; *POST-translational modification

Source: EMBO Journal. 11/2/2022, Vol. 41 Issue 21, p1-19. 19p.

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E2/E3‐independent ubiquitin‐like protein conjugation by Urm1 is directly coupled to cysteine persulfidation.

Authors : Ravichandran, Keerthiraju E^1,2 (AUTHOR); Kaduhr, Lars³ (AUTHOR); Skupien‐Rabian, Bozena¹ (AUTHOR)

Subjects: *TRANSFER RNA; *UBIQUITINATION; *CARRIER proteins

Source: EMBO Journal. 10/17/2022, Vol. 41 Issue 20, p1-23. 23p.

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SHP‐1 dephosphorylates histone H2B to facilitate its ubiquitination during transcription.

Authors : Tathe, Prajakta^1,2 (AUTHOR); Chowdary, K V S Rammohan¹ (AUTHOR); Murmu, Krushna Chandra³ (AUTHOR)

Subjects: *UBIQUITINATION; *UBIQUITIN-conjugating enzymes; *RNA polymerases

Source: EMBO Journal. 10/4/2022, Vol. 41 Issue 19, p1-21. 21p.

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نتائج البحث

فلترة النتائج

Determinants of chemoselectivity in ubiquitination by the J2 family of ubiquitin-conjugating enzymes.

RHEB neddylation by the UBE2F-SAG axis enhances mTORC1 activity and aggravates liver tumorigenesis.

Functional conservation and divergence of the helix‐turn‐helix motif of E2 ubiquitin‐conjugating enzymes.

Shared and distinct mechanisms of UBA1 inactivation across different diseases.

Structural basis for RAD18 regulation by MAGEA4 and its implications for RING ubiquitin ligase binding by MAGE family proteins.

The SMC5/6 complex recruits the PAF1 complex to facilitate DNA double‐strand break repair in Arabidopsis.

The UBA domain of conjugating enzyme Ubc1/Ube2K facilitates assembly of K48/K63‐branched ubiquitin chains.

A non‐canonical scaffold‐type E3 ligase complex mediates protein UFMylation.

E2/E3‐independent ubiquitin‐like protein conjugation by Urm1 is directly coupled to cysteine persulfidation.

SHP‐1 dephosphorylates histone H2B to facilitate its ubiquitination during transcription.

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