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  • 1-10 ل  550 نتائج ل ""DNA damage""

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Academic Journal

Bone morphogenetic protein signaling is required for RAD51-mediated maintenance of genome integrity in vascular endothelial cells.

Subjects: Rare Diseases; Genetics; 2.1 Biological and endogenous factors

  • Source: Communications biology. 1(1)

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Academic Journal

Genome-scale CRISPR knockout screen identifies TIGAR as a modifier of PARP inhibitor sensitivity.

Subjects: Humans; DNA Damage; Piperazines

  • Source: Communications biology. 2(1)

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Academic Journal

Enzyme-free release of adhered cells from standard culture dishes using intermittent ultrasonic traveling waves.

Subjects: CHO Cells; Animals; Cricetulus

  • Source: Communications biology. 2(1)

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Academic Journal

A large CRISPR-induced bystander mutation causes immune dysregulation

Subjects: Biomedical and Clinical Sciences; Immunology; Biotechnology

  • Source: Communications Biology. 2(1)

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Academic Journal

Sumoylation regulates the stability and nuclease activity of Saccharomyces cerevisiae Dna2.

  • Authors : Ranjha L; 1Institute for Research in Biomedicine, Università della Svizzera italiana (USI), Faculty of Biomedical Sciences, Via Vincenzo Vela 6, 6500 Bellinzona, Switzerland.; Levikova M

Subjects: DNA Helicases/DNA Helicases/DNA Helicases/*chemistry ; DNA Helicases/DNA Helicases/DNA Helicases/*metabolism ; Saccharomyces cerevisiae/Saccharomyces cerevisiae/Saccharomyces cerevisiae/*enzymology

  • Source: Communications biology [Commun Biol] 2019 May 08; Vol. 2, pp. 174. Date of Electronic Publication: 2019 May 08 (Print Publication: 2019).Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: eCollection Cited Medium: Internet ISSN:

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Academic Journal

Identifying the murine mammary cell target of metformin exposure.

  • Authors : Shehata M; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7 Canada.; Kim H

Subjects: Hypoglycemic Agents/Hypoglycemic Agents/Hypoglycemic Agents/*pharmacology ; Mammary Glands, Animal/Mammary Glands, Animal/Mammary Glands, Animal/*drug effects ; Mammary Neoplasms, Animal/Mammary Neoplasms, Animal/Mammary Neoplasms, Animal/*drug therapy

  • Source: Communications biology [Commun Biol] 2019 May 20; Vol. 2, pp. 192. Date of Electronic Publication: 2019 May 20 (Print Publication: 2019).Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: eCollection Cited Medium: Internet ISSN:

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Academic Journal

Deep learning-based selection of human sperm with high DNA integrity.

  • Authors : McCallum C; 1Department of Mechanical and Industrial Engineering, University of Toronto, 5 King's College Road, Toronto, ON Canada M5S 3G8.; Riordon J

Subjects: Deep Learning*; DNA/DNA/DNA/*analysis ; Spermatozoa/Spermatozoa/Spermatozoa/*metabolism

  • Source: Communications biology [Commun Biol] 2019 Jul 03; Vol. 2, pp. 250. Date of Electronic Publication: 2019 Jul 03 (Print Publication: 2019).Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: eCollection Cited Medium: Internet ISSN:

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Academic Journal

Pre-existing H4K16ac levels in euchromatin drive DNA repair by homologous recombination in S-phase.

  • Authors : Horikoshi N; 1Department of Radiation Oncology, The Houston Methodist Research Institute, Houston, TX 77030 USA.; 5Present Address: Department of Radiation Oncology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 USA.

Subjects: DNA Breaks, Double-Stranded* ; DNA Repair* ; Homologous Recombination*

  • Source: Communications biology [Commun Biol] 2019 Jul 05; Vol. 2, pp. 253. Date of Electronic Publication: 2019 Jul 05 (Print Publication: 2019).Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: eCollection Cited Medium: Internet ISSN:

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Academic Journal

Targeting p16-induced senescence prevents cigarette smoke-induced emphysema by promoting IGF1/Akt1 signaling in mice.

  • Authors : Cottage CT; 1Research and Early Development, Respiratory, Inflammation and Autoimmune (RIA), BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD 20878 United States.; Peterson N

Subjects: Cellular Senescence* ; Signal Transduction*; Cyclin-Dependent Kinase Inhibitor p16/Cyclin-Dependent Kinase Inhibitor p16/Cyclin-Dependent Kinase Inhibitor p16/*metabolism

  • Source: Communications biology [Commun Biol] 2019 Aug 09; Vol. 2, pp. 307. Date of Electronic Publication: 2019 Aug 09 (Print Publication: 2019).Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: eCollection Cited Medium: Internet ISSN:

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Academic Journal

Cep55 overexpression promotes genomic instability and tumorigenesis in mice

Subjects: Biopsy; Gene Expression; Expression

  • Source: Commun Biol

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