نتائج البحث

Evaluation of Drug-Drug Interaction Potential of Enarodustat (JTZ-951) Using a Cytochrome P450 Probe Cocktail.

• Authors : Pai SM; Clinical Pharmacology, Akros Pharma, Inc., Princeton, New Jersey, USA.; Yamada H

Subjects: Cytochrome P-450 CYP1A2*/Cytochrome P-450 CYP1A2*/Cytochrome P-450 CYP1A2*/metabolism ; Cytochrome P-450 CYP2D6*/Cytochrome P-450 CYP2D6*/Cytochrome P-450 CYP2D6*/metabolism; Humans

• Source: Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2023 Jul; Vol. 12 (7), pp. 667-682. Date of Electronic Publication: 2023 Jun 02.Publisher: Wiley Country of Publication: United States NLM ID: 101572899 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Evaluation of Deutetrabenazine's Potential to Delay Cardiac Repolarization Using Concentration-QTc Analysis.

• Authors : Schneider F; Teva Pharmaceutical Industries Ltd, Berlin, Germany.; Darpo B

Subjects: Cytochrome P-450 CYP2D6* ; Huntington Disease*/Huntington Disease*/Huntington Disease*/drug therapy; Adult

• Source: Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2023 Jan; Vol. 12 (1), pp. 94-106. Date of Electronic Publication: 2022 Sep 13.Publisher: Wiley Country of Publication: United States NLM ID: 101572899 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Impact of Paroxetine, a Strong CYP2D6 Inhibitor, on SPN‐812 (Viloxazine Extended‐Release) Pharmacokinetics in Healthy Adults.

• Authors : Wang, Zhao¹ (AUTHOR); Kosheleff, Alisa R.¹ (AUTHOR); Adeojo, Lilian W.¹ (AUTHOR)

• Source: Clinical Pharmacology in Drug Development. Nov2021, Vol. 10 Issue 11, p1365-1374. 10p.

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Pharmacokinetic Evaluation of the CYP3A4 and CYP2D6 Drug-Drug Interaction and CYP3A4 Induction Potential of Omecamtiv Mecarbil: Two Open-Label Studies in Healthy Subjects.

• Authors : Trivedi A; Amgen Inc., Thousand Oaks, California, USA.; Malik FI

Subjects: Cytochrome P-450 CYP2D6* ; Cytochrome P-450 CYP3A*; Drug Interactions

• Source: Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2022 Feb; Vol. 11 (2), pp. 185-193. Date of Electronic Publication: 2021 Jun 19.Publisher: Wiley Country of Publication: United States NLM ID: 101572899 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Characterization of the Effect of Upadacitinib on the Pharmacokinetics of Bupropion, a Sensitive Cytochrome P450 2B6 Probe Substrate.

• Authors : Mohamed MF; AbbVie Inc., North Chicago, Illinois, USA.; Minocha M

Subjects: Bupropion/Bupropion/Bupropion/*pharmacokinetics ; Cytochrome P-450 CYP2B6/Cytochrome P-450 CYP2B6/Cytochrome P-450 CYP2B6/*drug effects ; Cytochrome P-450 CYP2D6 Inhibitors/Cytochrome P-450 CYP2D6 Inhibitors/Cytochrome P-450 CYP2D6 Inhibitors/*pharmacokinetics

• Source: Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2021 Mar; Vol. 10 (3), pp. 299-306. Date of Electronic Publication: 2020 Jul 09.Publisher: Wiley Country of Publication: United States NLM ID: 101572899 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Population Pharmacokinetic Modeling and Exposure‐Response Analysis for Aripiprazole Once Monthly in Subjects With Schizophrenia.

• Authors : Wang, Xiaofeng; Raoufinia, Arash; Bihorel, Sébastien

Subjects: BIOAVAILABILITY; ARIPIPRAZOLE; CYTOCHROME P-450

• Source: Clinical Pharmacology in Drug Development; Feb2022, Vol. 11 Issue 2, p150-164, 15p

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A Cocktail Interaction Study Evaluating the Drug-Drug Interaction Potential of the Perpetrator Drug ASP8477 at Multiple Ascending Dose Levels.

• Authors : Treijtel N; Department of Clinical Pharmacology and Exploratory Development, Astellas Pharma Europe BV, Leiden, The Netherlands.; Collins C

Subjects: Dextromethorphan/Dextromethorphan/Dextromethorphan/*administration & dosage ; Losartan/Losartan/Losartan/*administration & dosage ; Midazolam/Midazolam/Midazolam/*administration & dosage

• Source: Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2019 May; Vol. 8 (4), pp. 529-540. Date of Electronic Publication: 2019 Feb 07.Publisher: Wiley Country of Publication: United States NLM ID: 101572899 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Tramadol Hydrochloride at Steady State Lacks Clinically Relevant QTc Interval Increases in Healthy Adults.

• Authors : Massarella J; Janssen Research & Development, LLC, Raritan, NJ, USA.; Ariyawansa J

Subjects: Long QT Syndrome*; Analgesics, Opioid/Analgesics, Opioid/Analgesics, Opioid/*administration & dosage ; Heart/Heart/Heart/*drug effects

• Source: Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2019 Jan; Vol. 8 (1), pp. 95-106. Date of Electronic Publication: 2018 May 18.Publisher: Wiley Country of Publication: United States NLM ID: 101572899 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Impact of Paroxetine, a Strong CYP2D6 Inhibitor, on SPN‐812 (Viloxazine Extended‐Release) Pharmacokinetics in Healthy Adults

• Authors : Stefan Schwabe; Alisa R Kosheleff; Peibing Qin

Subjects: Adult; Male; CYP2D6

• Source: Clinical Pharmacology in Drug Development

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Single-Dose Pharmacokinetic Study of Tramadol Extended-Release Tablets in Children and Adolescents.

• Authors : Vandenbossche J; Janssen Research & Development, Beerse, Belgium. .; Van Peer A

Subjects: Analgesics, Opioid/Analgesics, Opioid/Analgesics, Opioid/*administration & dosage ; Pain/Pain/Pain/*drug therapy ; Tramadol/Tramadol/Tramadol/*administration & dosage

• Source: Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2016 Sep; Vol. 5 (5), pp. 343-53. Date of Electronic Publication: 2016 Jun 12.Publisher: Wiley Country of Publication: United States NLM ID: 101572899 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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