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Academic Journal

TGFβ1 Restores Energy Homeostasis of Human Trophoblast Cells Under Hyperglycemia In Vitro by Inducing PPARγ Expression, AMPK Activation, and HIF1α Degradation.

Authors : Khiat N; Groupe de Recherche en Signalisation Cellulaire (GRSC), Département de Biologie Médicale, Université du Québec à Trois-Rivières, 3351 Boulevard des Forges, Trois-Rivières, QC G8Z 4M3, Canada.; Centre de Recherche Interuniversitaire en Reproduction et Développement-Réseau Québécois en Reproduction (CIRD-RQR), Université de Montréal, St-Hyacinthe, QC J2S 2M2, Canada.

Subjects: Trophoblasts*/Trophoblasts*/Trophoblasts*/metabolism ; Trophoblasts*/Trophoblasts*/Trophoblasts*/drug effects ; Hypoxia-Inducible Factor 1, alpha Subunit*/Hypoxia-Inducible Factor 1, alpha Subunit*/Hypoxia-Inducible Factor 1, alpha Subunit*/metabolism

Source: Cells [Cells] 2025 Jan 03; Vol. 14 (1). Date of Electronic Publication: 2025 Jan 03.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

Molecular Markers in Embryo Non-Development: Analysis of Gene Expressions ( Ki-67 , hTERT , HIF-1α ) in Spent Embryo Culture Medium.

Authors : Kılıç NÖ; Department of Histology and Embryology, Medical Faculty, Maltepe University, 34844 İstanbul, Turkey.; Kütük D

Subjects: Hypoxia-Inducible Factor 1, alpha Subunit*/Hypoxia-Inducible Factor 1, alpha Subunit*/Hypoxia-Inducible Factor 1, alpha Subunit*/metabolism ; Hypoxia-Inducible Factor 1, alpha Subunit*/Hypoxia-Inducible Factor 1, alpha Subunit*/Hypoxia-Inducible Factor 1, alpha Subunit*/genetics ; Telomerase*/Telomerase*/Telomerase*/metabolism

Source: Cells [Cells] 2024 Dec 18; Vol. 13 (24). Date of Electronic Publication: 2024 Dec 18.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

Single-Cell RNA Sequencing Reveals HIF1A as a Severity-Sensitive Immunological Scar in Circulating Monocytes of Convalescent Comorbidity-Free COVID-19 Patients.

Authors : May L; Leibniz Institute for Natural Products Research and Infection Biology, Department of Infection Immunology, 07745 Jena, Germany.; Center for Translational Cancer Research (TranslaTUM) & Institute of Virology, Technical University of Munich, 81675 Munich, Germany.

Subjects: COVID-19*; Humans ; SARS-CoV-2

Source: Cells [Cells] 2024 Feb 06; Vol. 13 (4). Date of Electronic Publication: 2024 Feb 06.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

USP10 Contributes to Colon Carcinogenesis via mTOR/S6K Mediated HIF-1α but Not HIF-2α Protein Synthesis.

Authors : Kubaichuk K; Faculty of Biochemistry and Molecular Biology, University of Oulu, 90570 Oulu, Finland.; Kietzmann T

Subjects: Colonic Neoplasms*/Colonic Neoplasms*/Colonic Neoplasms*/pathology; Humans ; Carcinogenesis

Source: Cells [Cells] 2023 Jun 08; Vol. 12 (12). Date of Electronic Publication: 2023 Jun 08.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

Normoxic HIF-1α Stabilization Caused by Local Inflammatory Factors and Its Consequences in Human Coronary Artery Endothelial Cells.

Authors : Abdi Sarabi M; Department of Internal Medicine, Division of Cardiology and Angiology, Otto-von-Guericke University, 39120 Magdeburg, Germany.; Shiri A

Subjects: Endothelial Cells*/Endothelial Cells*/Endothelial Cells*/metabolism ; Hypoxia-Inducible Factor 1, alpha Subunit*/Hypoxia-Inducible Factor 1, alpha Subunit*/Hypoxia-Inducible Factor 1, alpha Subunit*/metabolism; Humans

Source: Cells [Cells] 2022 Dec 01; Vol. 11 (23). Date of Electronic Publication: 2022 Dec 01.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

HIF-1α Regulates Bone Homeostasis and Angiogenesis, Participating in the Occurrence of Bone Metabolic Diseases.

Authors : Chen W; Microsurgery & Reconstruction Research Center, Xiangya Hospital, Central South University, Changsha 410008, China.; Wu P

Subjects: Hypoxia-Inducible Factor 1, alpha Subunit* ; Metabolic Diseases*; Humans

Source: Cells [Cells] 2022 Nov 10; Vol. 11 (22). Date of Electronic Publication: 2022 Nov 10.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

HOCI Probe CPP Induces the Differentiation of Human Dermal Fibroblasts into Vascular Endothelial Cells through PHD2/HIF-1α/HEY1 Signaling Pathway.

Authors : Cui X; Shandong Provincial Key Laboratory of Animal Cells and Developmental Biology, School of Life Science, Shandong University, Qingdao 266237, China.; Wen J

Subjects: Endothelial Cells*/Endothelial Cells*/Endothelial Cells*/metabolism ; Hypoxia-Inducible Factor-Proline Dioxygenases*; Humans

Source: Cells [Cells] 2022 Oct 04; Vol. 11 (19). Date of Electronic Publication: 2022 Oct 04.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

HIF-1α Stabilization in Flagellin-Stimulated Human Bronchial Cells Impairs Barrier Function.

Authors : Ramirez-Moral I; Center of Experimental and Molecular Medicine, Amsterdam Infection & Immunity Institute, Amsterdam UMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.; Ferreira BL

Subjects: Bronchi*/Bronchi*/Bronchi*/cytology ; Flagellin*/Flagellin*/Flagellin*/pharmacology ; Hypoxia-Inducible Factor 1, alpha Subunit*/Hypoxia-Inducible Factor 1, alpha Subunit*/Hypoxia-Inducible Factor 1, alpha Subunit*/metabolism

Source: Cells [Cells] 2022 Jan 24; Vol. 11 (3). Date of Electronic Publication: 2022 Jan 24.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

Identification of the Cysteine Protease Legumain as a Potential Chronic Hypoxia-Specific Multiple Myeloma Target Gene.

Authors : Clees AS; Department of Medicine, Hematology/Oncology, University Hospital Frankfurt, Goethe-University Frankfurt, 60590 Frankfurt, Germany.; Stolp V

Subjects: Molecular Targeted Therapy*; Cysteine Endopeptidases/Cysteine Endopeptidases/Cysteine Endopeptidases/*genetics ; Multiple Myeloma/Multiple Myeloma/Multiple Myeloma/*enzymology

Source: Cells [Cells] 2022 Jan 15; Vol. 11 (2). Date of Electronic Publication: 2022 Jan 15.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

miR-140-5p Attenuates Hypoxia-Induced Breast Cancer Progression by Targeting Nrf2/HO-1 Axis in a Keap1-Independent Mechanism.

Authors : Mahajan M; Redox Biology Laboratory, National Centre for Cell Science (NCCS), Pune 411007, India.; Sitasawad S

Subjects: Disease Progression*; Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*genetics ; Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*pathology

Source: Cells [Cells] 2021 Dec 22; Vol. 11 (1). Date of Electronic Publication: 2021 Dec 22.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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نتائج البحث

فلترة النتائج

TGFβ1 Restores Energy Homeostasis of Human Trophoblast Cells Under Hyperglycemia In Vitro by Inducing PPARγ Expression, AMPK Activation, and HIF1α Degradation.

Molecular Markers in Embryo Non-Development: Analysis of Gene Expressions ( Ki-67 , hTERT , HIF-1α ) in Spent Embryo Culture Medium.

Single-Cell RNA Sequencing Reveals HIF1A as a Severity-Sensitive Immunological Scar in Circulating Monocytes of Convalescent Comorbidity-Free COVID-19 Patients.

USP10 Contributes to Colon Carcinogenesis via mTOR/S6K Mediated HIF-1α but Not HIF-2α Protein Synthesis.

Normoxic HIF-1α Stabilization Caused by Local Inflammatory Factors and Its Consequences in Human Coronary Artery Endothelial Cells.

HIF-1α Regulates Bone Homeostasis and Angiogenesis, Participating in the Occurrence of Bone Metabolic Diseases.

HOCI Probe CPP Induces the Differentiation of Human Dermal Fibroblasts into Vascular Endothelial Cells through PHD2/HIF-1α/HEY1 Signaling Pathway.

HIF-1α Stabilization in Flagellin-Stimulated Human Bronchial Cells Impairs Barrier Function.

Identification of the Cysteine Protease Legumain as a Potential Chronic Hypoxia-Specific Multiple Myeloma Target Gene.

miR-140-5p Attenuates Hypoxia-Induced Breast Cancer Progression by Targeting Nrf2/HO-1 Axis in a Keap1-Independent Mechanism.

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