نتائج البحث

Functional role of coupling the endothelial TRPV4 and KCa3.1 channels in regulating coronary vascular tone.

• Authors : Mao, Aiqin¹ (AUTHOR); He, Dongxu¹ (AUTHOR); Zhang, Ka¹ (AUTHOR)

• Source: British Journal of Pharmacology. Sep2023, Vol. 180 Issue 17, p2266-2279. 14p. 2 Charts, 2 Graphs.

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TRPV1 and TRPM8 antagonists reduce cystitis‐induced bladder hypersensitivity via inhibition of different sensitised classes of bladder afferents in guinea pigs.

• Authors : Ramsay, Stewart¹ (AUTHOR); Keightley, Lauren¹ (AUTHOR); Brookes, Simon¹ (AUTHOR)

• Source: British Journal of Pharmacology. Jun2023, Vol. 180 Issue 11, p1482-1499. 18p. 10 Graphs.

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KS0365, a novel activator of the transient receptor potential vanilloid 3 (TRPV3) channel, accelerates keratinocyte migration.

• Authors : Maier M; Medical Faculty, Rudolf-Boehm-Institute of Pharmacology and Toxicology, Leipzig University, Leipzig, Germany.; Olthoff S

Subjects: Keratinocytes* ; TRPV Cation Channels*/TRPV Cation Channels*/TRPV Cation Channels*/agonists ; TRPV Cation Channels*/TRPV Cation Channels*/TRPV Cation Channels*/physiology

• Source: British journal of pharmacology [Br J Pharmacol] 2022 Dec; Vol. 179 (24), pp. 5290-5304. Date of Electronic Publication: 2022 Sep 20.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381

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Structural determinants of TRPV4 inhibition and identification of new antagonists with antiviral activity.

• Authors : Doñate‐Macian, Pablo¹ (AUTHOR); Duarte, Yorley^2,3 (AUTHOR); Rubio‐Moscardo, Fanny¹ (AUTHOR)

• Source: British Journal of Pharmacology. Jul2022, Vol. 179 Issue 14, p3576-3591. 16p. 4 Diagrams, 7 Graphs.

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Glucosylsphingosine evokes pruritus via activation of 5-HT 2A receptor and TRPV4 in sensory neurons.

• Authors : Sanjel B; College of Pharmacy, Gachon University, Incheon, South Korea.; Gachon Institute of Pharmaceutical Sciences, Incheon, South Korea.

Subjects: Pruritus*/Pruritus*/Pruritus*/chemically induced ; Pruritus*/Pruritus*/Pruritus*/metabolism ; Psychosine*/Psychosine*/Psychosine*/analogs & derivatives

• Source: British journal of pharmacology [Br J Pharmacol] 2022 May; Vol. 179 (10), pp. 2193-2207. Date of Electronic Publication: 2022 Feb 04.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381

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Transient Receptor Potential channels, TRPV1 and TRPA1 in melanocytes synergize UV‐dependent and UV‐independent melanogenesis.

• Authors : Jia, Qi^1,2 (AUTHOR); Tian, Weifeng^3,4 (AUTHOR); Li, Binbin⁵ (AUTHOR)

• Source: British Journal of Pharmacology. Dec2021, Vol. 178 Issue 23, p4646-4662. 17p. 6 Graphs.

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20-hydroxyeicosatetraenoic acid (20-HETE) is a pivotal endogenous ligand for TRPV1-mediated neurogenic inflammation in the skin.

• Authors : Hamers A; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Primus CP

Subjects: Hydroxyeicosatetraenoic Acids*/Hydroxyeicosatetraenoic Acids*/Hydroxyeicosatetraenoic Acids*/metabolism ; Hydroxyeicosatetraenoic Acids*/Hydroxyeicosatetraenoic Acids*/Hydroxyeicosatetraenoic Acids*/pharmacology ; Neurogenic Inflammation*/Neurogenic Inflammation*/Neurogenic Inflammation*/chemically induced

• Source: British journal of pharmacology [Br J Pharmacol] 2022 Apr; Vol. 179 (7), pp. 1450-1469. Date of Electronic Publication: 2022 Feb 14.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381

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Oxoglaucine alleviates osteoarthritis by activation of autophagy via blockade of Ca 2+ influx and TRPV5/calmodulin/CAMK-II pathway.

• Authors : Eid N; Department of Anatomy, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, UAE.; Ito Y

Subjects: Apomorphine*/Apomorphine*/Apomorphine*/analogs & derivatives ; Apomorphine*/Apomorphine*/Apomorphine*/therapeutic use ; Calcium-Calmodulin-Dependent Protein Kinase Type 2*/Calcium-Calmodulin-Dependent Protein Kinase Type 2*/Calcium-Calmodulin-Dependent Protein Kinase Type 2*/metabolism

• Source: British journal of pharmacology [Br J Pharmacol] 2022 Mar; Vol. 179 (6), pp. 1282-1283. Date of Electronic Publication: 2021 Nov 03.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381

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Mitochondria regulate TRPV4-mediated release of ATP.

• Authors : Zhang X; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, UK.; Lee MD

Subjects: Calcium Signaling* ; TRPV Cation Channels*/TRPV Cation Channels*/TRPV Cation Channels*/metabolism; Adenosine Triphosphate/Adenosine Triphosphate/Adenosine Triphosphate/metabolism

• Source: British journal of pharmacology [Br J Pharmacol] 2022 Mar; Vol. 179 (5), pp. 1017-1032. Date of Electronic Publication: 2021 Nov 02.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381

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Surfactant cocamide monoethanolamide causes eye irritation by activating nociceptor TRPV1 channels.

• Authors : Zhao, Fang¹ (AUTHOR) ; Wang, Shuangyan¹ (AUTHOR) ; Li, Yan¹ (AUTHOR)

• Source: British Journal of Pharmacology. Sep2021, Vol. 178 Issue 17, p3448-3462. 15p. 2 Diagrams, 3 Graphs.

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