نتائج البحث

Assessment of re‐aggregated human pancreatic islets for secondary drug screening.

• Authors : Ramachandran, K.^1,2; Peng, X.³; Bokvist, K.³

• Source: British Journal of Pharmacology. Jun2014, Vol. 171 Issue 12, p3010-3022. 13p. 5 Charts, 9 Graphs.

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Assessment of re-aggregated human pancreatic islets for secondary drug screening

• Authors : K Ramachandran; X Peng; L Stehno-Bittel

Subjects: Pharmacology; endocrine system; medicine.medical_specialty

• Source: British Journal of Pharmacology. 171:3010-3022

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Inhibition of the hyaluronan matrix enhances metabolic anticancer therapy by dichloroacetate in vitro and in vivo.

• Authors : Twarock S; Institut für Pharmakologie und Klinische Pharmakologie, Universitätsklinikum der Heinrich-Heine-Universität, Düsseldorf, Germany.; Reichert C

Subjects: Esophageal Neoplasms/Esophageal Neoplasms/Esophageal Neoplasms/*drug therapy ; Esophageal Squamous Cell Carcinoma/Esophageal Squamous Cell Carcinoma/Esophageal Squamous Cell Carcinoma/*drug therapy ; Extracellular Matrix/Extracellular Matrix/Extracellular Matrix/*drug effects

• Source: British journal of pharmacology [Br J Pharmacol] 2019 Dec; Vol. 176 (23), pp. 4474-4490. Date of Electronic Publication: 2019 Dec 09.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381

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A non-covalent inhibitor XMU-MP-3 overrides ibrutinib-resistant Btk C481S mutation in B-cell malignancies.

• Authors : Gui F; State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, State-Province Joint Engineering Laboratory of Targeted Drugs from Natural Products, School of Life Science, Xiamen University, Xiamen, China.; Jiang J

Subjects: Agammaglobulinaemia Tyrosine Kinase/Agammaglobulinaemia Tyrosine Kinase/Agammaglobulinaemia Tyrosine Kinase/*antagonists & inhibitors ; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Drug Resistance, Neoplasm/Drug Resistance, Neoplasm/Drug Resistance, Neoplasm/*drug effects

• Source: British journal of pharmacology [Br J Pharmacol] 2019 Dec; Vol. 176 (23), pp. 4491-4509. Date of Electronic Publication: 2019 Dec 09.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381

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A novel 2-aminobenzimidazole-based compound Jzu 17 exhibits anti-angiogenesis effects by targeting VEGFR-2 signalling.

• Authors : Lien JC; School of Pharmacy, China Medical University, Taichung, Taiwan.; Department of Medical Research, Hospital of China Medical University, Taichung, Taiwan.

Subjects: Angiogenesis Inhibitors/Angiogenesis Inhibitors/Angiogenesis Inhibitors/*pharmacology ; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Lung Neoplasms/Lung Neoplasms/Lung Neoplasms/*drug therapy

• Source: British journal of pharmacology [Br J Pharmacol] 2019 Oct; Vol. 176 (20), pp. 4034-4049. Date of Electronic Publication: 2019 Sep 15.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381

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Salinomycin exerts anti-colorectal cancer activity by targeting the β-catenin/T-cell factor complex.

• Authors : Wang Z; Guangdong Key Laboratory for Genome Stability & Disease Prevention, Carson International Cancer Center, Department of Pharmacology, Shenzhen University Health Science Center, Shenzhen, China.; Zhou L

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Colorectal Neoplasms/Colorectal Neoplasms/Colorectal Neoplasms/*drug therapy ; Pyrans/Pyrans/Pyrans/*pharmacology

• Source: British journal of pharmacology [Br J Pharmacol] 2019 Sep; Vol. 176 (17), pp. 3390-3406. Date of Electronic Publication: 2019 Jul 24.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381

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Epigenetic events involved in organic cation transporter 1-dependent impaired response of hepatocellular carcinoma to sorafenib.

• Authors : Al-Abdulla R; Experimental Hepatology and Drug Targeting (HEVEFARM), IBSAL, University of Salamanca, Salamanca, Spain.; Lozano E

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/*drug therapy ; Epigenesis, Genetic/Epigenesis, Genetic/Epigenesis, Genetic/*drug effects

• Source: British journal of pharmacology [Br J Pharmacol] 2019 Mar; Vol. 176 (6), pp. 787-800. Date of Electronic Publication: 2019 Feb 11.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381

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Ex vivo culture of cells derived from circulating tumour cell xenograft to support small cell lung cancer research and experimental therapeutics.

• Authors : Lallo A; Clinical and Experimental Pharmacology Group, Cancer Research UK Manchester Institute, University of Manchester, Macclesfield, UK.; Gulati S

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Indazoles/Indazoles/Indazoles/*pharmacology ; Lung Neoplasms/Lung Neoplasms/Lung Neoplasms/*drug therapy

• Source: British journal of pharmacology [Br J Pharmacol] 2019 Feb; Vol. 176 (3), pp. 436-450. Date of Electronic Publication: 2018 Dec 13.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381

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Systems analysis of phosphorylation-regulated Bcl-2 interactions establishes a model to reconcile the controversy over the significance of Bcl-2 phosphorylation.

• Authors : Song T; State Key Laboratory of Fine Chemicals, School of Chemistry, Dalian University of Technology, Dalian, China.; Wang P

Subjects: Models, Biological* ; Surface Plasmon Resonance*; Proto-Oncogene Proteins c-bcl-2/Proto-Oncogene Proteins c-bcl-2/Proto-Oncogene Proteins c-bcl-2/*metabolism

• Source: British journal of pharmacology [Br J Pharmacol] 2019 Feb; Vol. 176 (3), pp. 491-504. Date of Electronic Publication: 2018 Dec 26.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381

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Discovery and pharmacological characterization of a novel series of highly selective inhibitors of cyclin-dependent kinases 4 and 6 as anticancer agents.

• Authors : Tadesse S; Centre for Drug Discovery and Development, Sansom Institute for Health Research, School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, SA, Australia.; Bantie L

Subjects: Drug Discovery*; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Cyclin-Dependent Kinase 4/Cyclin-Dependent Kinase 4/Cyclin-Dependent Kinase 4/*antagonists & inhibitors

• Source: British journal of pharmacology [Br J Pharmacol] 2018 Jun; Vol. 175 (12), pp. 2399-2413. Date of Electronic Publication: 2018 May 08.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381

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