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Academic Journal

Leveraging multi-omics data to empower quantitative systems pharmacology in immuno-oncology.

  • Authors : Arulraj T; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.; Wang H

Subjects: Neoplasms*/Neoplasms*/Neoplasms*/drug therapy ; Neoplasms*/Neoplasms*/Neoplasms*/genetics ; Pharmacology*

  • Source: Briefings in bioinformatics [Brief Bioinform] 2024 Mar 27; Vol. 25 (3).Publisher: Oxford University Press Country of Publication: England NLM ID: 100912837 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Novel systems biology experimental pipeline reveals matairesinol's antimetastatic potential in prostate cancer: an integrated approach of network pharmacology, bioinformatics, and experimental validation.

  • Authors : Rajadnya R; Cancer Biology, Interactive Research School for Health Affairs (IRSHA), Bharati Vidyapeeth (Deemed to be University), Pune-Satara Road, Dhankawadi, Pune, Maharashtra 411043, India.; Sharma N

Subjects: Prostatic Neoplasms*/Prostatic Neoplasms*/Prostatic Neoplasms*/drug therapy ; Prostatic Neoplasms*/Prostatic Neoplasms*/Prostatic Neoplasms*/pathology ; Prostatic Neoplasms*/Prostatic Neoplasms*/Prostatic Neoplasms*/metabolism

  • Source: Briefings in bioinformatics [Brief Bioinform] 2024 Jul 25; Vol. 25 (5).Publisher: Oxford University Press Country of Publication: England NLM ID: 100912837 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

DEWNA: dynamic entropy weight network analysis and its application to the DNA-binding proteome in A549 cells with cisplatin-induced damage.

  • Authors : Wang S; Department of General Surgery and Liver Transplant Center, Proteomics-Metabolomics Analysis Platform, NHC Key Lab of Transplant Engineering and Immunology, West China Hospital, Sichuan University, Chengdu, China.; Institutes for Systems Genetics, Frontiers Science Center for Disease-Related Molecular Network, West China Hospital, Sichuan University, Chengdu, China.

Subjects: Cisplatin*/Cisplatin*/Cisplatin*/pharmacology ; DNA Damage* ; Proteome*/Proteome*/Proteome*/metabolism

  • Source: Briefings in bioinformatics [Brief Bioinform] 2024 Sep 23; Vol. 25 (6).Publisher: Oxford University Press Country of Publication: England NLM ID: 100912837 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Eravacycline, an antibacterial drug, repurposed for pancreatic cancer therapy: insights from a molecular-based deep learning model.

  • Authors : Jabarin A; Department of Clinical Biochemistry and Pharmacology, Ben-Gurion University of the Negev (BGU), P.O.B. 653, Beer-Sheva 8410501, Israel.; Shtar G

Subjects: Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/drug therapy ; Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/pathology ; Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/metabolism

  • Source: Briefings in bioinformatics [Brief Bioinform] 2024 Mar 27; Vol. 25 (3).Publisher: Oxford University Press Country of Publication: England NLM ID: 100912837 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

A granularity-level information fusion strategy on hypergraph transformer for predicting synergistic effects of anticancer drugs.

  • Authors : Wang W; College of Computer and Information Engineering, Henan Normal University, 453007 Xinxiang, China.; Key Laboratory of Artificial Intelligence and Personalized Learning in Education of Henan Province  453007, China.

Subjects: Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology; Antineoplastic Combined Chemotherapy Protocols/Antineoplastic Combined Chemotherapy Protocols/Antineoplastic Combined Chemotherapy Protocols/pharmacology ; Cell Line

  • Source: Briefings in bioinformatics [Brief Bioinform] 2023 Nov 22; Vol. 25 (1).Publisher: Oxford University Press Country of Publication: England NLM ID: 100912837 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Machine learning for synergistic network pharmacology: a comprehensive overview.

  • Authors : Noor F; Department of Bioinformatics and Biotechnology, Government College University, Faisalabad 38000, Pakistan.; Asif M

Subjects: Network Pharmacology* ; Pharmacology*/Pharmacology*/Pharmacology*/methods; Drug Discovery/Drug Discovery/Drug Discovery/methods

  • Source: Briefings in bioinformatics [Brief Bioinform] 2023 May 19; Vol. 24 (3).Publisher: Oxford University Press Country of Publication: England NLM ID: 100912837 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Optimized patient-specific immune checkpoint inhibitor therapies for cancer treatment based on tumor immune microenvironment modeling.

  • Authors : Yao Y; School of Data Science, City University of Hong Kong, Kowloon, Hong Kong SAR 00001, China.; Chen YF

Subjects: Tumor Microenvironment*/Tumor Microenvironment*/Tumor Microenvironment*/immunology ; Immune Checkpoint Inhibitors*/Immune Checkpoint Inhibitors*/Immune Checkpoint Inhibitors*/therapeutic use ; Immune Checkpoint Inhibitors*/Immune Checkpoint Inhibitors*/Immune Checkpoint Inhibitors*/pharmacology

  • Source: Briefings in bioinformatics [Brief Bioinform] 2024 Sep 23; Vol. 25 (6).Publisher: Oxford University Press Country of Publication: England NLM ID: 100912837 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

BANDRP: a bilinear attention network for anti-cancer drug response prediction based on fingerprint and multi-omics.

  • Authors : Cao C; Hunan Provincial Key Lab on Bioinformatics, School of Computer Science and Engineering, Central South University, Changsha 410083, China.; Zhao H

Subjects: Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/therapeutic use ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology; Humans

  • Source: Briefings in bioinformatics [Brief Bioinform] 2024 Sep 23; Vol. 25 (6).Publisher: Oxford University Press Country of Publication: England NLM ID: 100912837 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Herb-CMap: a multimodal fusion framework for deciphering the mechanisms of action in traditional Chinese medicine using Suhuang antitussive capsule as a case study.

  • Authors : Wang Y; Department of TCMs Pharmaceuticals, School of Traditional Chinese Pharmacy, China Pharmaceutical University, No. 639 Longmian Avenue, Nanjing 211198, PR China.; Sui Y

Subjects: Drugs, Chinese Herbal*/Drugs, Chinese Herbal*/Drugs, Chinese Herbal*/pharmacology ; Drugs, Chinese Herbal*/Drugs, Chinese Herbal*/Drugs, Chinese Herbal*/therapeutic use ; Medicine, Chinese Traditional*/Medicine, Chinese Traditional*/Medicine, Chinese Traditional*/methods

  • Source: Briefings in bioinformatics [Brief Bioinform] 2024 Jul 25; Vol. 25 (5).Publisher: Oxford University Press Country of Publication: England NLM ID: 100912837 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Designing antimicrobial peptides using deep learning and molecular dynamic simulations.

  • Authors : Cao Q; Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, 5 Yushan Road, Qingdao 266003, China.; Qingdao National Laboratory for Marine Science and Technology, Qingdao 266003, China.

Subjects: Anti-Bacterial Agents*/Anti-Bacterial Agents*/Anti-Bacterial Agents*/pharmacology ; Deep Learning*; Antimicrobial Cationic Peptides/Antimicrobial Cationic Peptides/Antimicrobial Cationic Peptides/pharmacology

  • Source: Briefings in bioinformatics [Brief Bioinform] 2023 Mar 19; Vol. 24 (2).Publisher: Oxford University Press Country of Publication: England NLM ID: 100912837 Publication Model: Print Cited Medium: Internet ISSN:

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