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Academic Journal

Current perspectives in drug targeting intrinsically disordered proteins and biomolecular condensates.

  • Authors : Qin C; Department of Radiation Oncology, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, 510655, People's Republic of China.; GuangDong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, 510655, People's Republic of China.

Subjects: Intrinsically Disordered Proteins*/Intrinsically Disordered Proteins*/Intrinsically Disordered Proteins*/metabolism ; Intrinsically Disordered Proteins*/Intrinsically Disordered Proteins*/Intrinsically Disordered Proteins*/chemistry ; Biomolecular Condensates*/Biomolecular Condensates*/Biomolecular Condensates*/metabolism

  • Source: BMC biology [BMC Biol] 2025 May 06; Vol. 23 (1), pp. 118. Date of Electronic Publication: 2025 May 06.Publisher: BioMed Central Country of Publication: England NLM ID: 101190720 Publication Model: Electronic Cited Medium: Internet ISSN: 1741-7007

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Academic Journal

Motif-guided identification of KRAS-interacting proteins.

  • Source: BMC Biology. 11/19/2024, Vol. 22 Issue 1, p1-16. 16p.

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Academic Journal

CTCF-mediated insulation and chromatin environment modulate Car5b escape from X inactivation.

  • Authors : Fang H; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, 98195, USA.; Tronco AR

Subjects: Chromatin*/Chromatin*/Chromatin*/metabolism ; Chromatin*/Chromatin*/Chromatin*/genetics ; X Chromosome Inactivation*/X Chromosome Inactivation*/X Chromosome Inactivation*/genetics

  • Source: BMC biology [BMC Biol] 2025 Mar 03; Vol. 23 (1), pp. 68. Date of Electronic Publication: 2025 Mar 03.Publisher: BioMed Central Country of Publication: England NLM ID: 101190720 Publication Model: Electronic Cited Medium: Internet ISSN: 1741-7007

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Academic Journal

Another tail of two sites: activation of the Notch ligand Delta by Mindbomb1.

  • Authors : Vüllings N; Institute of Genetics, Heinrich-Heine-Universitaet Duesseldorf, Universitaetsstr. 1, Duesseldorf, 40225, Germany.; Airich A

Subjects: Drosophila*/Drosophila*/Drosophila*/growth & development ; Drosophila*/Drosophila*/Drosophila*/metabolism ; Receptors, Notch*/Receptors, Notch*/Receptors, Notch*/metabolism

  • Source: BMC biology [BMC Biol] 2025 Mar 06; Vol. 23 (1), pp. 71. Date of Electronic Publication: 2025 Mar 06.Publisher: BioMed Central Country of Publication: England NLM ID: 101190720 Publication Model: Electronic Cited Medium: Internet ISSN: 1741-7007

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Academic Journal

LADS: a powerful vaccine platform for cancer immunotherapy and prevention.

  • Authors : Sun J; Key Laboratory of Applied Biotechnology on Animal Science & Veterinary Medicine of Zhejiang Province, Zhejiang Engineering Research Center for Veterinary Diagnostics & Advanced Technology, Zhejiang International Science and Technology Cooperation Base for Veterinary Medicine and Health Management, Belt and Road International Joint Laboratory for One Health and Food Safety, China-Australia Joint Laboratory for Animal Health Big Data Analytics, College of Veterinary Medicine, Zhejiang A&F University, 666 Wusu Street, Lin'an District, Hangzhou, Zhejiang Province, 311300, China.; Wang J

Subjects: Cancer Vaccines*/Cancer Vaccines*/Cancer Vaccines*/immunology ; Immunotherapy*/Immunotherapy*/Immunotherapy*/methods ; Papillomavirus E7 Proteins*/Papillomavirus E7 Proteins*/Papillomavirus E7 Proteins*/immunology

  • Source: BMC biology [BMC Biol] 2024 Dec 18; Vol. 22 (1), pp. 291. Date of Electronic Publication: 2024 Dec 18.Publisher: BioMed Central Country of Publication: England NLM ID: 101190720 Publication Model: Electronic Cited Medium: Internet ISSN: 1741-7007

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Academic Journal

PPARα regulates YAP protein levels and activity by affecting its ubiquitination modification.

  • Authors : Zhou W; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening & Guangdong-Hongkong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, 510515, China.; Department of Pharmacy, The Sixth Affiliated Hospital, School of Medicine, South China University of Technology, Foshan, 528200, China.

Subjects: Ubiquitination* ; PPAR alpha*/PPAR alpha*/PPAR alpha*/metabolism ; PPAR alpha*/PPAR alpha*/PPAR alpha*/genetics

  • Source: BMC biology [BMC Biol] 2025 Feb 28; Vol. 23 (1), pp. 64. Date of Electronic Publication: 2025 Feb 28.Publisher: BioMed Central Country of Publication: England NLM ID: 101190720 Publication Model: Electronic Cited Medium: Internet ISSN: 1741-7007

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Academic Journal

The crotonylated and succinylated proteins of jujube involved in phytoplasma-stress responses.

  • Authors : Zhang L; College of Life Science, Hebei Agricultural University, Baoding, China.; Hebei Key Laboratory of Plant Physiology and Molecular Pathology, Hebei Agricultural University, Baoding, China.

Subjects: Ziziphus*/Ziziphus*/Ziziphus*/microbiology ; Ziziphus*/Ziziphus*/Ziziphus*/metabolism ; Phytoplasma*/Phytoplasma*/Phytoplasma*/physiology

  • Source: BMC biology [BMC Biol] 2024 May 15; Vol. 22 (1), pp. 113. Date of Electronic Publication: 2024 May 15.Publisher: BioMed Central Country of Publication: England NLM ID: 101190720 Publication Model: Electronic Cited Medium: Internet ISSN: 1741-7007

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