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Academic Journal

CLN5 and CLN3 function as a complex to regulate endolysosome function.

  • Authors : Yasa S; Centre Armand-Frappier Santé Biotechnologie, Institut national de la recherche scientifique, Laval H7V 1B7, Canada.; Sauvageau E

Subjects: Adaptor Proteins, Signal Transducing/Adaptor Proteins, Signal Transducing/Adaptor Proteins, Signal Transducing/*metabolism ; Adaptor Proteins, Vesicular Transport/Adaptor Proteins, Vesicular Transport/Adaptor Proteins, Vesicular Transport/*metabolism ; Endosomes/Endosomes/Endosomes/*metabolism

  • Source: The Biochemical journal [Biochem J] 2021 Jun 25; Vol. 478 (12), pp. 2339-2357.Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R Publication Model: Print Cited

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Academic Journal

The biophysical basis of receptor tyrosine kinase ligand functional selectivity: Trk-B case study.

  • Authors : Ahmed F; Department of Materials Science and Engineering, Johns Hopkins University, 3400 Charles Street, Baltimore, MD 21218, U.S.A.; Institute for NanoBioTechnology, Johns Hopkins University, 3400 Charles Street, Baltimore, MD 21218, U.S.A.

Subjects: Protein Multimerization*; Brain-Derived Neurotrophic Factor/Brain-Derived Neurotrophic Factor/Brain-Derived Neurotrophic Factor/*metabolism ; Cell Membrane/Cell Membrane/Cell Membrane/*metabolism

  • Source: The Biochemical journal [Biochem J] 2020 Dec 11; Vol. 477 (23), pp. 4515-4526.Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R Publication Model: Print Cited

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Academic Journal

Activation of glycoprotein VI (GPVI) and C-type lectin-like receptor-2 (CLEC-2) underlies platelet activation by diesel exhaust particles and other charged/hydrophobic ligands.

  • Authors : Alshehri OM; Centre for Cardiovascular Sciences, Institute of Biomedical Research, The Medical School, University of Birmingham, Birmingham B15 2TT, U.K.; Montague S

Subjects: Air Pollutants/Air Pollutants/Air Pollutants/*toxicity ; CD36 Antigens/CD36 Antigens/CD36 Antigens/*chemistry ; Coagulants/Coagulants/Coagulants/*pharmacology

  • Source: The Biochemical journal [Biochem J] 2015 Jun 15; Vol. 468 (3), pp. 459-73. Date of Electronic Publication: 2015 Apr 07.Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R Publication Model:

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Academic Journal

LL-37-induced host cell cytotoxicity depends on cellular expression of the globular C1q receptor (p33).

  • Authors : Svensson D; Department of Experimental Medical Science, Lund University, BMC D12, SE-22184 Lund, Sweden.; Wilk L

Subjects: Antimicrobial Cationic Peptides/Antimicrobial Cationic Peptides/Antimicrobial Cationic Peptides/*toxicity ; Cell Membrane/Cell Membrane/Cell Membrane/*drug effects ; Cell Membrane/Cell Membrane/Cell Membrane/*metabolism

  • Source: The Biochemical journal [Biochem J] 2016 Jan 01; Vol. 473 (1), pp. 87-98. Date of Electronic Publication: 2015 Oct 27.Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R Publication Model:

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Academic Journal

Akt activation increases cellular cholesterol by promoting the proteasomal degradation of Niemann-Pick C1.

  • Authors : Du X; School of Biotechnology and Biomolecular Sciences, the University of New South Wales, Sydney, NSW 2052, Australia .; Zhang Y

Subjects: Proteolysis*; Carrier Proteins/Carrier Proteins/Carrier Proteins/*metabolism ; Cholesterol/Cholesterol/Cholesterol/*metabolism

  • Source: The Biochemical journal [Biochem J] 2015 Oct 15; Vol. 471 (2), pp. 243-53. Date of Electronic Publication: 2015 Aug 17.Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R Publication Model:

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Academic Journal

C/EBP homologous protein (CHOP) contributes to hepatocyte death via the promotion of ERO1α signalling in acute liver failure.

  • Authors : Rao J; Liver Transplantation Center of First Affiliated Hospital and Translational Medicine Research Center of Jiangning Hospital, Nanjing Medical University, Nanjing 210029, People's Republic of China.; Zhang C

Subjects: MAP Kinase Signaling System*; Glycoproteins/Glycoproteins/Glycoproteins/*metabolism ; Hepatocytes/Hepatocytes/Hepatocytes/*metabolism

  • Source: The Biochemical journal [Biochem J] 2015 Mar 01; Vol. 466 (2), pp. 369-78.Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R Publication Model: Print Cited

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Academic Journal

Identification of NOX2 regions for normal biosynthesis of cytochrome b558 in phagocytes highlighting essential residues for p22phox binding.

  • Authors : Beaumel S; Chronic Granulomatous Disease Diagnosis and Research Centre, Therex-TIMC/Imag, UMR CNRS 5525, Université Grenoble Alpes, Grenoble, F-38041, France.; Grunwald D

Subjects: Protein Interaction Domains and Motifs*/Protein Interaction Domains and Motifs*/Protein Interaction Domains and Motifs*/genetics; Cytochrome b Group/Cytochrome b Group/Cytochrome b Group/*biosynthesis ; Membrane Glycoproteins/Membrane Glycoproteins/Membrane Glycoproteins/*chemistry

  • Source: The Biochemical journal [Biochem J] 2014 Dec 15; Vol. 464 (3), pp. 425-37.Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R Publication Model: Print Cited

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Academic Journal

Hepatocyte growth factor activator inhibitor type 2 (HAI-2) modulates hepcidin expression by inhibiting the cell surface protease matriptase-2.

  • Authors : Maurer E; Pharmaceutical Institute, University of Bonn, An der Immenburg 4, 53121 Bonn, Germany.; Gütschow M

Subjects: Antimicrobial Cationic Peptides/Antimicrobial Cationic Peptides/Antimicrobial Cationic Peptides/*genetics ; Membrane Glycoproteins/Membrane Glycoproteins/Membrane Glycoproteins/*physiology ; Membrane Proteins/Membrane Proteins/Membrane Proteins/*antagonists & inhibitors

  • Source: The Biochemical journal [Biochem J] 2013 Mar 15; Vol. 450 (3), pp. 583-93.Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R Publication Model: Print Cited

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Academic Journal

Insights into the regulation of the matriptase-prostasin proteolytic system.

  • Authors : Holt-Danborg L; Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3, DK-2200 Copenhagen N, Denmark.; Skovbjerg S

Subjects: Proteolysis*; Enzyme Precursors/Enzyme Precursors/Enzyme Precursors/*metabolism ; Serine Endopeptidases/Serine Endopeptidases/Serine Endopeptidases/*metabolism

  • Source: The Biochemical journal [Biochem J] 2020 Nov 27; Vol. 477 (22), pp. 4349-4365.Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R Publication Model: Print Cited

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