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Academic Journal

Dietary fructose as a risk factor for non-alcoholic fatty liver disease (NAFLD).

  • Authors : Alwahsh SM; Faculty of Medicine, Institute of Biochemistry, University of Leipzig, Johannisallee 30, 04103, Leipzig, Germany. .; MCR Centre for Regenerative Medicine, University of Edinburgh, 5 Little France Dr, EH16 4UU Edinburgh, UK. .

Subjects: Fructose/Fructose/Fructose/*adverse effects ; Non-alcoholic Fatty Liver Disease/Non-alcoholic Fatty Liver Disease/Non-alcoholic Fatty Liver Disease/*etiology ; Sweetening Agents/Sweetening Agents/Sweetening Agents/*adverse effects

  • Source: Archives of toxicology [Arch Toxicol] 2017 Apr; Vol. 91 (4), pp. 1545-1563. Date of Electronic Publication: 2016 Dec 19.Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Editorial & Opinion

Pharmacogenetics in early drug development for non-alcoholic steatohepatitis: missed chances and future opportunities.

  • Authors : Boeckmans J; In Vitro Liver Disease Modelling Team, Department of In Vitro Toxicology and Dermato-Cosmetology, Faculty of Medicine and Pharmacy, Vrije Universiteit Brussel, Laarbeeklaan 103, 1090, Brussels, Belgium. .; Metabolic Liver Research Center, Department of Medicine, University Medical Center Mainz, Mainz, Germany. .

Subjects: Pharmacogenetics* ; Non-alcoholic Fatty Liver Disease*/Non-alcoholic Fatty Liver Disease*/Non-alcoholic Fatty Liver Disease*/drug therapy ; Non-alcoholic Fatty Liver Disease*/Non-alcoholic Fatty Liver Disease*/Non-alcoholic Fatty Liver Disease*/genetics

  • Source: Archives of toxicology [Arch Toxicol] 2023 Jun; Vol. 97 (6), pp. 1825-1827. Date of Electronic Publication: 2023 May 06.Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Metabolic signature of HepaRG cells exposed to ethanol and tumor necrosis factor alpha to study alcoholic steatohepatitis by LC-MS-based untargeted metabolomics.

  • Authors : Iturrospe E; Toxicological Centre, University of Antwerp, Universiteitsplein 1, 2610, Antwerp, Belgium. .; Department of In Vitro Toxicology and Dermato-Cosmetology, Vrije Universiteit Brussel, Laarbeeklaan 103, 1090, Jette, Belgium. .

Subjects: Fatty Liver, Alcoholic*/Fatty Liver, Alcoholic*/Fatty Liver, Alcoholic*/metabolism ; Fatty Liver, Alcoholic*/Fatty Liver, Alcoholic*/Fatty Liver, Alcoholic*/pathology ; Non-alcoholic Fatty Liver Disease*/Non-alcoholic Fatty Liver Disease*/Non-alcoholic Fatty Liver Disease*/metabolism

  • Source: Archives of toxicology [Arch Toxicol] 2023 May; Vol. 97 (5), pp. 1335-1353. Date of Electronic Publication: 2023 Feb 24.Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Inflammation-associated suppression of metabolic gene networks in acute and chronic liver disease.

  • Authors : Campos G; IfADo-Leibniz Research Centre for Working Environment and Human Factors, Technical University Dortmund, Ardeystrasse 67, 44139, Dortmund, Germany.; Schmidt-Heck W

Subjects: Gene Regulatory Networks*; Chemical and Drug Induced Liver Injury, Chronic/Chemical and Drug Induced Liver Injury, Chronic/Chemical and Drug Induced Liver Injury, Chronic/*genetics ; Hepatitis, Chronic/Hepatitis, Chronic/Hepatitis, Chronic/*genetics

  • Source: Archives of toxicology [Arch Toxicol] 2020 Jan; Vol. 94 (1), pp. 205-217. Date of Electronic Publication: 2020 Jan 09.Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Inflammation-associated suppression of metabolic gene networks in acute and chronic liver disease

Subjects: Liver Cirrhosis; Male; 0301 basic medicine

  • Source: Campos, G, Schmidt-Heck, W, De Smedt, J, Widera, A, Ghallab, A, Pütter, L, González, D, Edlund, K, Cadenas, C, Marchan, R, Guthke, R, Verfaillie, C, Hetz, C, Sachinidis, A, Braeuning, A, Schwarz, M,

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