نتائج البحث

Early life interventions metformin and trodusquemine metabolically reprogram the developing mouse liver through transcriptomic alterations.

• Authors : Ashiqueali SA; Burnett School of Biomedical Sciences, University of Central Florida College of Medicine, Orlando, Florida, USA.; Schneider A

Subjects: Liver*/Liver*/Liver*/metabolism ; Liver*/Liver*/Liver*/drug effects ; Metformin*/Metformin*/Metformin*/pharmacology

• Source: Aging cell [Aging Cell] 2024 Sep; Vol. 23 (9), pp. e14227. Date of Electronic Publication: 2024 May 27.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Metformin treatment results in distinctive skeletal muscle mitochondrial remodeling in rats with different intrinsic aerobic capacities.

• Authors : Bubak MP; Aging and Metabolism Research Program, The Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA.; Davidyan A

Subjects: Metformin*/Metformin*/Metformin*/pharmacology ; Muscle, Skeletal*/Muscle, Skeletal*/Muscle, Skeletal*/drug effects ; Muscle, Skeletal*/Muscle, Skeletal*/Muscle, Skeletal*/metabolism

• Source: Aging cell [Aging Cell] 2024 Sep; Vol. 23 (9), pp. e14235. Date of Electronic Publication: 2024 Jun 24.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Cell‐type specific impact of metformin on monocyte epigenetic age reversal in virally suppressed older people living with HIV.

• Authors : Corley, Michael J.¹ (AUTHOR); Pang, Alina P. S.¹ (AUTHOR); Shikuma, Cecilia M.² (AUTHOR)

• Source: Aging Cell. Jan2024, Vol. 23 Issue 1, p1-5. 5p.

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Disuse‐induced muscle fibrosis, cellular senescence, and senescence‐associated secretory phenotype in older adults are alleviated during re‐ambulation with metformin pre‐treatment.

• Authors : Petrocelli, Jonathan J.¹ (AUTHOR); McKenzie, Alec I.¹ (AUTHOR); de Hart, Naomi M. M. P.² (AUTHOR)

• Source: Aging Cell. Nov2023, Vol. 22 Issue 11, p1-13. 13p.

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Metformin has heterogeneous effects on model organism lifespans and is beneficial when started at an early age in Caenorhabditis elegans: A systematic review and meta‐analysis.

• Authors : Parish, Austin J.^1,2 (AUTHOR) ; Swindell, William R.³ (AUTHOR)

• Source: Aging Cell. Dec2022, Vol. 21 Issue 12, p1-10. 10p.

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Rapamycin/metformin co‐treatment normalizes insulin sensitivity and reduces complications of metabolic syndrome in type 2 diabetic mice

• Authors : Reifsnyder, Peter C; Flurkey, Kevin; Doty, Rosalinda

Subjects: Biomedical and Clinical Sciences; Clinical Sciences; Diabetes

• Source: Aging Cell. 21(9)

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Metformin treatment of diverse Caenorhabditis species reveals the importance of genetic background in longevity and healthspan extension outcomes.

• Authors : Onken, Brian¹ (AUTHOR); Sedore, Christine A.² (AUTHOR); Coleman‐Hulbert, Anna L.² (AUTHOR)

• Source: Aging Cell. Jan2022, Vol. 21 Issue 1, p1-11. 11p.

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Metformin inhibits chronic kidney disease‐induced DNA damage and senescence of mesenchymal stem cells.

• Authors : Kim, Hyoungnae^1,2 (AUTHOR); Yu, Mi Ra² (AUTHOR); Lee, Haekyung¹ (AUTHOR)

• Source: Aging Cell. Feb2021, Vol. 20 Issue 2, p1-12. 12p.

تفاصيل العنوان

Metformin induces S-adenosylmethionine restriction to extend the Caenorhabditis elegans healthspan through H3K4me3 modifiers.

• Authors : Xiao Y; Institute of life sciences, Zunyi Medical University, Zunyi, China.; Guizhou Provincial College-based Key Lab for Tumor Prevention and Treatment with Distinctive Medicines, Zunyi Medical University, Zunyi, China.

Subjects: Caenorhabditis elegans Proteins*/Caenorhabditis elegans Proteins*/Caenorhabditis elegans Proteins*/genetics ; Caenorhabditis elegans Proteins*/Caenorhabditis elegans Proteins*/Caenorhabditis elegans Proteins*/metabolism ; Diabetes Mellitus, Type 2*/Diabetes Mellitus, Type 2*/Diabetes Mellitus, Type 2*/drug therapy

• Source: Aging cell [Aging Cell] 2022 Mar; Vol. 21 (3), pp. e13567. Date of Electronic Publication: 2022 Feb 11.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Metformin treatment in late middle age improves cognitive function with alleviation of microglial activation and enhancement of autophagy in the hippocampus.

• Authors : Kodali, Maheedhar¹ (AUTHOR); Attaluri, Sahithi¹ (AUTHOR); Madhu, Leelavathi N.¹ (AUTHOR)

• Source: Aging Cell. Feb2021, Vol. 20 Issue 2, p1-19. 19p.

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