نتائج البحث

Blood-brain barrier dysfunction in aging is mediated by brain endothelial senescence.

• Authors : Novo JP; CNC-UC Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal.; University of Coimbra, Institute for Interdisciplinary Research, Doctoral Programme in Experimental Biology and Biomedicine (PDBEB), Coimbra, Portugal.

Subjects: Blood-Brain Barrier*/Blood-Brain Barrier*/Blood-Brain Barrier*/metabolism ; Cellular Senescence*/Cellular Senescence*/Cellular Senescence*/physiology ; Aging*/Aging*/Aging*/physiology

• Source: Aging cell [Aging Cell] 2024 Sep; Vol. 23 (9), pp. e14270. Date of Electronic Publication: 2024 Aug 15.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Homocysteine potentiates amyloid β -induced death receptor 4- and 5-mediated cerebral endothelial cell apoptosis, blood brain barrier dysfunction and angiogenic impairment.

• Authors : Carey A; Department of Neural Sciences, Alzheimer's Center at Temple, Temple University Lewis Katz School of Medicine, Philadelphia, Pennsylvania, USA.; Parodi-Rullan R

Subjects: Amyloid beta-Peptides*/Amyloid beta-Peptides*/Amyloid beta-Peptides*/metabolism ; Apoptosis* ; Blood-Brain Barrier*/Blood-Brain Barrier*/Blood-Brain Barrier*/drug effects

• Source: Aging cell [Aging Cell] 2024 May; Vol. 23 (5), pp. e14106. Date of Electronic Publication: 2024 Feb 15.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Exosomal miR‐532‐5p induced by long‐term exercise rescues blood–brain barrier function in 5XFAD mice via downregulation of EPHA4.

• Authors : Liang, Xiaoyan¹ (AUTHOR); Fa, Wenxin² (AUTHOR); Wang, Nan¹ (AUTHOR)

• Source: Aging Cell. Jan2023, Vol. 22 Issue 1, p1-16. 16p.

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Blood–brain barrier dysfunction promotes astrocyte senescence through albumin‐induced TGFβ signaling activation.

• Authors : Preininger, Marcela K.^1,2 (AUTHOR); Zaytseva, Dasha^1,3 (AUTHOR); Lin, Jessica May¹ (AUTHOR)

• Source: Aging Cell. Feb2023, Vol. 22 Issue 2, p1-14. 14p.

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miR‐195 reduces age‐related blood–brain barrier leakage caused by thrombospondin‐1‐mediated selective autophagy.

• Authors : Chen, Chien‐Yuan¹ (AUTHOR); Chao, Yung‐Mei² (AUTHOR); Lin, Hsiu‐Fen^3,4 (AUTHOR)

• Source: Aging Cell. Nov2020, Vol. 19 Issue 11, p1-17. 17p.

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Alzheimer's amyloid β heterogeneous species differentially affect brain endothelial cell viability, blood‐brain barrier integrity, and angiogenesis.

• Authors : Parodi‐Rullán, Rebecca¹ (AUTHOR); Ghiso, Jorge^2,3 (AUTHOR); Cabrera, Erwin² (AUTHOR)

• Source: Aging Cell. Nov2020, Vol. 19 Issue 11, p1-15. 15p.

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High‐fat diet protects the blood–brain barrier in an Alzheimer's disease mouse model.

• Authors : Elhaik Goldman, Shirin^1,2; Goez, David³; Last, David³

• Source: Aging Cell. Oct2018, Vol. 17 Issue 5, p1-1. 10p.

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Melatonin alleviates lipopolysaccharide-compromised integrity of blood-brain barrier through activating AMP-activated protein kinase in old mice.

• Authors : Wang, Xiaona¹; Xue, Gai‐Xiu²; Liu, Wen‐Cao³

• Source: Aging Cell. Apr2017, Vol. 16 Issue 2, p414-421. 8p.

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Accelerated cerebromicrovascular senescence contributes to cognitive decline in a mouse model of paclitaxel (Taxol)‐induced chemobrain.

• Authors : Ahire, Chetan^1,2 (AUTHOR); Nyul‐Toth, Adam^1,2,3,4 (AUTHOR); DelFavero, Jordan^1,2 (AUTHOR)

• Source: Aging Cell. Jul2023, Vol. 22 Issue 7, p1-15. 15p.

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Enhanced microglial pro-inflammatory response to lipopolysaccharide correlates with brain infiltration and blood-brain barrier dysregulation in a mouse model of telomere shortening.

• Authors : Raj, Divya D. A.¹; Moser, Jill^2,3; Pol, Susanne M. A.⁴

• Source: Aging Cell. Dec2015, Vol. 14 Issue 6, p1003-1013. 11p.

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