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Academic Journal

WSS25, a sulfated polysaccharide, inhibits RANKL-induced mouse osteoclast formation by blocking SMAD/ID1 signaling.

Authors : Chen C; Glycochemistry and Glycobiology Laboratory, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.; Institute of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.

Subjects: Bone Resorption/Bone Resorption/Bone Resorption/*drug therapy ; Glucans/Glucans/Glucans/*pharmacology ; Inhibitor of Differentiation Protein 1/Inhibitor of Differentiation Protein 1/Inhibitor of Differentiation Protein 1/*metabolism

Source: Acta pharmacologica Sinica [Acta Pharmacol Sin] 2015 Sep; Vol. 36 (9), pp. 1053-64. Date of Electronic Publication: 2015 Aug 24.Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 100956087 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Protease Omi cleaving Hax-1 protein contributes to OGD/R-induced mitochondrial damage in neuroblastoma N2a cells and cerebral injury in MCAO mice.

Authors : Wu JY; Laboratory of Molecular Neuropathology, Jiangsu Key Laboratory of Translational Research and Therapy for Neuro-Psycho-Diseases and College of Pharmaceutical Sciences, Soochow University, Suzhou 215021, China.; Li M

Subjects: Brain/Brain/Brain/*pathology ; Infarction, Middle Cerebral Artery/Infarction, Middle Cerebral Artery/Infarction, Middle Cerebral Artery/*metabolism ; Mitochondria/Mitochondria/Mitochondria/*pathology

Source: Acta pharmacologica Sinica [Acta Pharmacol Sin] 2015 Sep; Vol. 36 (9), pp. 1043-52. Date of Electronic Publication: 2015 Aug 24.Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 100956087 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Involvement of adrenoceptors, dopamine receptors and AMPA receptors in antidepressant-like action of 7-O-ethylfangchinoline in mice.

Authors : Sheng ZF; Department of Pharmacology, School of Basic Medical Science, Peking University, Beijing 100191, China.; Cui XY

Subjects: Antidepressive Agents/Antidepressive Agents/Antidepressive Agents/*pharmacology ; Benzylisoquinolines/Benzylisoquinolines/Benzylisoquinolines/*pharmacology ; Receptors, AMPA/Receptors, AMPA/Receptors, AMPA/*metabolism

Source: Acta pharmacologica Sinica [Acta Pharmacol Sin] 2015 Aug; Vol. 36 (8), pp. 949-56.Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 100956087 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Exogenous carbon monoxide suppresses Escherichia coli vitality and improves survival in an Escherichia coli-induced murine sepsis model.

Authors : Shen WC; Department of Burns and Plastic Surgery, Affiliated Hospital, Jiangsu University, Zhenjiang 212001, China.; Wang X

Subjects: Carbon Monoxide/Carbon Monoxide/Carbon Monoxide/*metabolism ; Escherichia coli/Escherichia coli/Escherichia coli/*drug effects ; Escherichia coli Infections/Escherichia coli Infections/Escherichia coli Infections/*drug therapy

Source: Acta pharmacologica Sinica [Acta Pharmacol Sin] 2014 Dec; Vol. 35 (12), pp. 1566-76. Date of Electronic Publication: 2014 Nov 17.Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 100956087 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

SHR3824, a novel selective inhibitor of renal sodium glucose cotransporter 2, exhibits antidiabetic efficacy in rodent models.

Authors : Yan PK; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.; Zhang LN

Subjects: Sodium-Glucose Transporter 2 Inhibitors*; Diabetes Mellitus, Experimental/Diabetes Mellitus, Experimental/Diabetes Mellitus, Experimental/*drug therapy ; Hypoglycemic Agents/Hypoglycemic Agents/Hypoglycemic Agents/*pharmacology

Source: Acta pharmacologica Sinica [Acta Pharmacol Sin] 2014 May; Vol. 35 (5), pp. 613-24.Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 100956087 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Exendin-4 ameliorates oxidized-LDL-induced inhibition of macrophage migration in vitro via the NF-κB pathway.

Authors : Ma GF; State Key Laboratory of Natural Medicines, School of Life Science and Technology, China Pharmaceutical University, Nanjing 210009, China.; Chen S

Subjects: Lipoproteins, LDL/Lipoproteins, LDL/Lipoproteins, LDL/*metabolism ; Macrophages/Macrophages/Macrophages/*drug effects ; NF-kappa B/NF-kappa B/NF-kappa B/*metabolism

Source: Acta pharmacologica Sinica [Acta Pharmacol Sin] 2014 Feb; Vol. 35 (2), pp. 195-202. Date of Electronic Publication: 2013 Dec 16.Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 100956087 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Exercise ameliorates the detrimental effect of chloroquine on skeletal muscles in mice via restoring autophagy flux.

Authors : Jiang D; Department of Pharmacology, Laboratory of Aging and Nervous Diseases (SZS0703), Soochow University School of Pharmaceutical Science, Suzhou 215123, China.; Chen K

Subjects: Autophagy/Autophagy/Autophagy/*physiology ; Chloroquine/Chloroquine/Chloroquine/*toxicity ; Muscle, Skeletal/Muscle, Skeletal/Muscle, Skeletal/*metabolism

Source: Acta pharmacologica Sinica [Acta Pharmacol Sin] 2014 Jan; Vol. 35 (1), pp. 135-42. Date of Electronic Publication: 2013 Dec 16.Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 100956087 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Autophagy and cathepsin L are involved in the antinociceptive effect of DMBC in a mouse acetic acid-writhing model.

Authors : Gu WW; Department of Pharmacology and Laboratory of Cerebrovascular Pharmacology, College of Pharmaceutical Science, Soochow University, Suzhou 215123, China.; Ao GZ

Subjects: Disease Models, Animal*; Acetic Acid/Acetic Acid/Acetic Acid/*toxicity ; Analgesics/Analgesics/Analgesics/*administration & dosage

Source: Acta pharmacologica Sinica [Acta Pharmacol Sin] 2013 Aug; Vol. 34 (8), pp. 1007-12.Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 100956087 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Pioglitazone ameliorates memory deficits in streptozotocin-induced diabetic mice by reducing brain β-amyloid through PPARγ activation.

Authors : Liu LP; Department of Pharmacy, the Second Hospital Affiliated to Anhui Medical University, Hefei 230031, China.; Yan TH

Subjects: Amyloid beta-Peptides/Amyloid beta-Peptides/Amyloid beta-Peptides/*metabolism ; Cerebral Cortex/Cerebral Cortex/Cerebral Cortex/*drug effects ; Diabetes Mellitus, Experimental/Diabetes Mellitus, Experimental/Diabetes Mellitus, Experimental/*drug therapy

Source: Acta pharmacologica Sinica [Acta Pharmacol Sin] 2013 Apr; Vol. 34 (4), pp. 455-63. Date of Electronic Publication: 2013 Mar 25.Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 100956087 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Acute and chronic administration of SHR117887, a novel and specific dipeptidyl peptidase-4 inhibitor, improves metabolic control in diabetic rodent models.

Authors : Liu X; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.; Zhang LN

Subjects: Disease Models, Animal*; Diabetes Mellitus, Type 2/Diabetes Mellitus, Type 2/Diabetes Mellitus, Type 2/*drug therapy ; Diabetes Mellitus, Type 2/Diabetes Mellitus, Type 2/Diabetes Mellitus, Type 2/*metabolism

Source: Acta pharmacologica Sinica [Acta Pharmacol Sin] 2012 Aug; Vol. 33 (8), pp. 1013-22. Date of Electronic Publication: 2012 Jul 30.Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 100956087 Publication Model: Print-Electronic Cited Medium: Internet

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نتائج البحث

فلترة النتائج

WSS25, a sulfated polysaccharide, inhibits RANKL-induced mouse osteoclast formation by blocking SMAD/ID1 signaling.

Protease Omi cleaving Hax-1 protein contributes to OGD/R-induced mitochondrial damage in neuroblastoma N2a cells and cerebral injury in MCAO mice.

Involvement of adrenoceptors, dopamine receptors and AMPA receptors in antidepressant-like action of 7-O-ethylfangchinoline in mice.

Exogenous carbon monoxide suppresses Escherichia coli vitality and improves survival in an Escherichia coli-induced murine sepsis model.

SHR3824, a novel selective inhibitor of renal sodium glucose cotransporter 2, exhibits antidiabetic efficacy in rodent models.

Exendin-4 ameliorates oxidized-LDL-induced inhibition of macrophage migration in vitro via the NF-κB pathway.

Exercise ameliorates the detrimental effect of chloroquine on skeletal muscles in mice via restoring autophagy flux.

Autophagy and cathepsin L are involved in the antinociceptive effect of DMBC in a mouse acetic acid-writhing model.

Pioglitazone ameliorates memory deficits in streptozotocin-induced diabetic mice by reducing brain β-amyloid through PPARγ activation.

Acute and chronic administration of SHR117887, a novel and specific dipeptidyl peptidase-4 inhibitor, improves metabolic control in diabetic rodent models.

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