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Electronic Resource

Limited sampling strategies for individualized BAX 855 prophylaxis in severe hemophilia A:in silico evaluation

Subjects: article

  • Source: Bukkems , L H , Goedhart , T M H J , Zwaan , C M , Cnossen , M H & Mathôt , R A A 2023 , ' Limited sampling strategies for individualized BAX 855 prophylaxis in severe

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Electronic Resource

Combined inhibition of BCL-2 and MCL-1 overcomes BAX deficiency-mediated resistance of TP53-mutant acute myeloid leukemia to individual BH3 mimetics

Subjects: Clinic for Oncology and Hematology; 610 Medicine & health; Journal Article

  • Source: Carter, Bing Z; Mak, Po Yee; Tao, Wenjing; Ayoub, Edward; Ostermann, Lauren B; Huang, Xuelin; Loghavi, Sanam; Boettcher, Steffen; Nishida, Yuki; Ruvolo, Vivian; Hughes, Paul E; Morrow, Phuong K;

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Modeling apoptosis resistance in CHO cells with CRISPR-mediated knockouts of Bak1, Bax, and Bok

Subjects: Apoptosis; Bayesian inference; Bioprocessing

  • Source: MacDonald , M A , Barry , C , Groves , T , Martínez , V S , Gray , P P , Baker , K , Shave , E , Mahler , S , Munro , T , Marcellin , E & Nielsen , L K 2022 , ' Modeling apoptosis resistance in CHO

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