نتائج البحث

The cancer-associated fibroblast facilitates YAP liquid-liquid phase separation to promote cancer cell stemness in HCC.

• Authors : Chen W; Department of Gastroenterology and Hepatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Road, No.1095, Wuhan, 430030, China.; School of Life Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, 999077, China.

Subjects: Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/pathology ; Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/genetics ; Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/metabolism

• Source: Cell communication and signaling : CCS [Cell Commun Signal] 2025 May 24; Vol. 23 (1), pp. 238. Date of Electronic Publication: 2025 May 24.Publisher: BioMed Central Country of Publication: England NLM ID: 101170464 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-811X

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The liprin-α/RIM complex regulates the dynamic assembly of presynaptic active zones via liquid-liquid phase separation.

• Authors : Jin G; Shenzhen Key Laboratory of Biomolecular Assembling and Regulation, Southern University of Science and Technology, Shenzhen, China.; Brain Research Center, Southern University of Science and Technology, Shenzhen, China.

Subjects: Presynaptic Terminals*/Presynaptic Terminals*/Presynaptic Terminals*/metabolism ; Adaptor Proteins, Signal Transducing*/Adaptor Proteins, Signal Transducing*/Adaptor Proteins, Signal Transducing*/metabolism ; Adaptor Proteins, Signal Transducing*/Adaptor Proteins, Signal Transducing*/Adaptor Proteins, Signal Transducing*/chemistry

• Source: PLoS biology [PLoS Biol] 2025 Jun 10; Vol. 23 (6), pp. e3002817. Date of Electronic Publication: 2025 Jun 10 (Print Publication: 2025).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101183755 Publication Model: eCollection Cited Medium: Internet

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LncRNA-MEG3 Regulates Muscle Mass and Metabolic Homeostasis by Facilitating SUZ12 Liquid-Liquid Phase Separation.

• Authors : Yao Y; Shenzhen Branch, Guangdong Laboratory of Lingnan Modern Agriculture, Key Laboratory of Livestock and Poultry Multi-omics of MARA, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen, 518124, China.; Kunpeng Institute of Modern Agriculture at Foshan, Chinese Academy of Agricultural Sciences, Foshan, 528226, China.

Subjects: RNA, Long Noncoding*/RNA, Long Noncoding*/RNA, Long Noncoding*/genetics ; RNA, Long Noncoding*/RNA, Long Noncoding*/RNA, Long Noncoding*/metabolism ; Homeostasis*/Homeostasis*/Homeostasis*/genetics

• Source: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2025 Jun; Vol. 12 (23), pp. e2417715. Date of Electronic Publication: 2025 Apr 26.Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844

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Yield of Protein Crystallization from Metastable Liquid-Liquid Phase Separation.

• Authors : Thomas S; Department of Chemistry and Biochemistry, Texas Christian University, Fort Worth, TX 76109, USA.; Dougay JA

Subjects: Muramidase*/Muramidase*/Muramidase*/chemistry ; Proteins*/Proteins*/Proteins*/chemistry; Crystallization

• Source: Molecules (Basel, Switzerland) [Molecules] 2025 May 29; Vol. 30 (11). Date of Electronic Publication: 2025 May 29.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Roles of Supersaturation and Liquid-Liquid Phase Separation for Enhanced Oral Absorption of Poorly Soluble Drugs from Amorphous Solid Dispersions.

• Authors : Kawakami K; Research Center for Macromolecules and Biomaterials, National Institute for Materials Science, 1-1 Namiki, Tsukuba 305-0044, Ibaraki, Japan.; Graduate School of Science and Technology, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8577, Ibaraki, Japan.

• Source: Pharmaceutics [Pharmaceutics] 2025 Feb 16; Vol. 17 (2). Date of Electronic Publication: 2025 Feb 16.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101534003 Publication Model: Electronic Cited Medium: Print ISSN: 1999-4923 (Print)

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RPS 2.0: an updated database of RNAs involved in liquid-liquid phase separation.

• Authors : He Y; School of Life Sciences, State Key Laboratory of Oncology in South China, Cancer Center, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University, Guangzhou 510060, China.; Bao X

Subjects: RNA*/RNA*/RNA*/metabolism ; RNA*/RNA*/RNA*/chemistry ; RNA*/RNA*/RNA*/genetics

• Source: Nucleic acids research [Nucleic Acids Res] 2025 Jan 06; Vol. 53 (D1), pp. D299-D309.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Liquid-liquid phase separation of microtubule-binding proteins in the regulation of spindle assembly.

• Authors : Sun S; Center for Cell Structure and Function, Shandong Provincial Key Laboratory of Animal Resistance Biology, Collaborative Innovation Center of Cell Biology in Universities of Shandong, Institute of Biomedical Sciences, College of Life Sciences, Shandong Normal University, Jinan, China.; Yang Y

Subjects: Spindle Apparatus*/Spindle Apparatus*/Spindle Apparatus*/metabolism ; Microtubules*/Microtubules*/Microtubules*/metabolism ; Microtubule-Associated Proteins*/Microtubule-Associated Proteins*/Microtubule-Associated Proteins*/metabolism

• Source: Cell proliferation [Cell Prolif] 2024 Oct; Vol. 57 (10), pp. e13649. Date of Electronic Publication: 2024 May 13.Publisher: Published for the Cell Kinetics Society, the European Study Group for Cell Proliferation, and the International Cell Cycle Society by Blackwell Scientific Publications

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Development and validation of a novel liquid-liquid phase separation gene signature for bladder cancer.

• Authors : Guo S; Department of Clinical Laboratory, First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, Guangxi, China.; Department of Clinical Laboratory, Songjiang Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 201600, China.

Subjects: Urinary Bladder Neoplasms*/Urinary Bladder Neoplasms*/Urinary Bladder Neoplasms*/genetics ; Urinary Bladder Neoplasms*/Urinary Bladder Neoplasms*/Urinary Bladder Neoplasms*/pathology ; Urinary Bladder Neoplasms*/Urinary Bladder Neoplasms*/Urinary Bladder Neoplasms*/mortality

• Source: Scientific reports [Sci Rep] 2024 Sep 29; Vol. 14 (1), pp. 22552. Date of Electronic Publication: 2024 Sep 29.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Role of liquid-liquid phase separation in cancer: Mechanisms and therapeutic implications.

• Authors : Li X; School of Clinical Medicine Tsinghua University Beijing China.; Yu Z

• Source: Cancer innovation [Cancer Innov] 2024 Sep 17; Vol. 3 (5), pp. e144. Date of Electronic Publication: 2024 Sep 17 (Print Publication: 2024).Publisher: John Wiley & Sons Australia, Ltd Country of Publication: England NLM ID: 9918713888606676 Publication Model: eCollection Cited Medium:

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Emerging roles of liquid-liquid phase separation in liver innate immunity.

• Authors : Zhang X; Department of Blood Transfusion, Xiangya Hospital, Central South University, 87 Xiangya Road, Changsha, Hunan Province, 410008, China.; NHC Key Laboratory of Cancer Proteomics, Xiangya Hospital, Central South University, 87 Xiangya Road, Changsha, Hunan Province, 410008, China.

Subjects: Immunity, Innate* ; Liver*/Liver*/Liver*/metabolism ; Liver*/Liver*/Liver*/immunology

• Source: Cell communication and signaling : CCS [Cell Commun Signal] 2024 Sep 03; Vol. 22 (1), pp. 430. Date of Electronic Publication: 2024 Sep 03.Publisher: BioMed Central Country of Publication: England NLM ID: 101170464 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-811X

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