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Academic Journal

Knockout or inhibition of DHPS suppresses ovarian tumor growth and metastasis by attenuating the TGFβ pathway.

  • Authors : Zhao G; Department of Pathology and Laboratory Medicine, Collage of Medicine, the University of Tennessee Health Science Center, Memphis, TN, 38163, United States.; Center for Cancer Research, Collage of Medicine, the University of Tennessee Health Science Center, Memphis, TN, 38163, USA.

Subjects: Ovarian Neoplasms*/Ovarian Neoplasms*/Ovarian Neoplasms*/pathology ; Ovarian Neoplasms*/Ovarian Neoplasms*/Ovarian Neoplasms*/genetics ; Ovarian Neoplasms*/Ovarian Neoplasms*/Ovarian Neoplasms*/metabolism

  • Source: Scientific reports [Sci Rep] 2025 Jan 06; Vol. 15 (1), pp. 917. Date of Electronic Publication: 2025 Jan 06.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

TGFβ-mediated inhibition of hypodermal adipocyte progenitor differentiation promotes wound-induced skin fibrosis.

  • Authors : Yin M; State Key Laboratory of Cellular Stress Biology, School of Pharmaceutical Sciences, Xiamen University, Xiamen, China.; Sun L

Subjects: Fibrosis* ; Transforming Growth Factor beta*/Transforming Growth Factor beta*/Transforming Growth Factor beta*/metabolism ; Cell Differentiation*/Cell Differentiation*/Cell Differentiation*/drug effects

  • Source: Cell proliferation [Cell Prolif] 2025 Jan; Vol. 58 (1), pp. e13722. Date of Electronic Publication: 2024 Jul 29.Publisher: Published for the Cell Kinetics Society, the European Study Group for Cell Proliferation, and the International Cell Cycle Society by Blackwell Scientific Publications

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Academic Journal

Kisspeptin Alleviates Human Hepatic Fibrogenesis by Inhibiting TGFβ Signaling in Hepatic Stellate Cells.

  • Authors : Prasad K; Department of Medicine, Robert Wood Johnson Medical School, Rutgers University, New Brunswick, NJ 08901, USA.; Bhattacharya D

Subjects: Hepatic Stellate Cells*/Hepatic Stellate Cells*/Hepatic Stellate Cells*/metabolism ; Hepatic Stellate Cells*/Hepatic Stellate Cells*/Hepatic Stellate Cells*/pathology ; Hepatic Stellate Cells*/Hepatic Stellate Cells*/Hepatic Stellate Cells*/drug effects

  • Source: Cells [Cells] 2024 Oct 04; Vol. 13 (19). Date of Electronic Publication: 2024 Oct 04.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

Lumican/Lumikine Promotes Healing of Corneal Epithelium Debridement by Upregulation of EGFR Ligand Expression via Noncanonical Smad-Independent TGFβ/TBRs Signaling.

  • Authors : Kao WWY; Department of Ophthalmology, University of Cincinnati, Cincinnati, OH 45267, USA.; Zhang J

Subjects: Lumican*/Lumican*/Lumican*/metabolism ; Epithelium, Corneal*/Epithelium, Corneal*/Epithelium, Corneal*/drug effects ; Epithelium, Corneal*/Epithelium, Corneal*/Epithelium, Corneal*/metabolism

  • Source: Cells [Cells] 2024 Sep 24; Vol. 13 (19). Date of Electronic Publication: 2024 Sep 24.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

45S5 Bioactive Glass-Ointment Positively Effects on Wound Healing in Rats by Regulating TNFα, Il-10, VEGF, and TGFβ.

  • Authors : Kırgız Ö; Department of Surgery, Faculty of Veterinary Medicine, Hatay Mustafa Kemal University, Hatay, Turkey.; Altuğ ME

Subjects: Wound Healing*/Wound Healing*/Wound Healing*/drug effects ; Vascular Endothelial Growth Factor A*/Vascular Endothelial Growth Factor A*/Vascular Endothelial Growth Factor A*/metabolism ; Vascular Endothelial Growth Factor A*/Vascular Endothelial Growth Factor A*/Vascular Endothelial Growth Factor A*/genetics

  • Source: Journal of clinical laboratory analysis [J Clin Lab Anal] 2024 Sep; Vol. 38 (17-18), pp. e25094. Date of Electronic Publication: 2024 Sep 05.Publisher: Wiley Country of Publication: United States NLM ID: 8801384 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-2825

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Academic Journal

ΔNp63 bookmarks and creates an accessible epigenetic environment for TGFβ-induced cancer cell stemness and invasiveness.

  • Authors : Vasilaki E; Department of Medical Biochemistry and Microbiology, Science for Life Laboratory, Uppsala University, Box 582, Uppsala, SE-751 23, Sweden. .; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, SE-751 85, Sweden. .

Subjects: Transforming Growth Factor beta*/Transforming Growth Factor beta*/Transforming Growth Factor beta*/metabolism ; Epigenesis, Genetic*/Epigenesis, Genetic*/Epigenesis, Genetic*/genetics ; Tumor Suppressor Proteins*/Tumor Suppressor Proteins*/Tumor Suppressor Proteins*/metabolism

  • Source: Cell communication and signaling : CCS [Cell Commun Signal] 2024 Aug 23; Vol. 22 (1), pp. 411. Date of Electronic Publication: 2024 Aug 23.Publisher: BioMed Central Country of Publication: England NLM ID: 101170464 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-811X

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Academic Journal

The TGFβ Induced MicroRNAome of the Trabecular Meshwork.

  • Authors : Doyle C; Centre for Genomic Medicine, Biomedical Sciences Research Institute, Ulster University, Coleraine Campus, Coleraine BT52 1SA, UK.; Callaghan B

Subjects: Trabecular Meshwork*/Trabecular Meshwork*/Trabecular Meshwork*/metabolism ; Trabecular Meshwork*/Trabecular Meshwork*/Trabecular Meshwork*/drug effects ; Trabecular Meshwork*/Trabecular Meshwork*/Trabecular Meshwork*/pathology

  • Source: Cells [Cells] 2024 Jun 19; Vol. 13 (12). Date of Electronic Publication: 2024 Jun 19.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

Multiple Endocrine Neoplasia Type 1 Regulates TGFβ-Mediated Suppression of Tumor Formation and Metastasis in Melanoma.

  • Authors : Boudreault J; Cancer Research Program, Department of Medicine, Research Institute of McGill University Health Center, Montreal, QC H4A 3J1, Canada.; Canaff L

Subjects: Melanoma*/Melanoma*/Melanoma*/genetics ; Melanoma*/Melanoma*/Melanoma*/pathology ; Melanoma*/Melanoma*/Melanoma*/metabolism

  • Source: Cells [Cells] 2024 Jun 04; Vol. 13 (11). Date of Electronic Publication: 2024 Jun 04.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

TSPYL1 as a Critical Regulator of TGFβ Signaling through Repression of TGFBR1 and TSPYL2.

  • Authors : Tan H; Department of Paediatrics and Adolescent Medicine, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.; Miao MX

Subjects: Receptor, Transforming Growth Factor-beta Type I*/Receptor, Transforming Growth Factor-beta Type I*/Receptor, Transforming Growth Factor-beta Type I*/metabolism ; Receptor, Transforming Growth Factor-beta Type I*/Receptor, Transforming Growth Factor-beta Type I*/Receptor, Transforming Growth Factor-beta Type I*/genetics ; Signal Transduction*/Signal Transduction*/Signal Transduction*/genetics

  • Source: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2024 Jun; Vol. 11 (21), pp. e2306486. Date of Electronic Publication: 2024 Apr 08.Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844

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Academic Journal

An Inherited Allele Confers Prostate Cancer Progression and Drug Resistance via RFX6/HOXA10-Orchestrated TGFβ Signaling.

  • Authors : Zhong M; MOE Key Laboratory of Metabolism and Molecular Medicine & Department of Biochemistry and Molecular Biology of School of Basic Medical Sciences, and Fudan University Shanghai Cancer Center, Cancer Institutes, Department of Oncology, Shanghai Medical College of Fudan University, Shanghai, 200032, China.; Xu W

Subjects: Alleles* ; Disease Progression* ; Drug Resistance, Neoplasm*/Drug Resistance, Neoplasm*/Drug Resistance, Neoplasm*/genetics

  • Source: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2024 Aug; Vol. 11 (32), pp. e2401492. Date of Electronic Publication: 2024 Jun 26.Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844

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