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Academic Journal

Cholesterol 25-Hydroxylase Protects Against Diabetic Kidney Disease by Regulating ADP Ribosylation Factor 4.

Authors : Zhang L; Department of Medicine, Division of Nephrology, Icahn School of Medicine at Mount Sinai, New York, NY, Box 1243, USA.; Fang Z

Subjects: ADP-Ribosylation Factors*/ADP-Ribosylation Factors*/ADP-Ribosylation Factors*/metabolism ; ADP-Ribosylation Factors*/ADP-Ribosylation Factors*/ADP-Ribosylation Factors*/genetics ; Diabetic Nephropathies*/Diabetic Nephropathies*/Diabetic Nephropathies*/metabolism

Source: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2024 Aug; Vol. 11 (29), pp. e2309642. Date of Electronic Publication: 2024 May 30.Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844

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Academic Journal

Characterization of two steroid hydroxylases from different Streptomyces spp. and their ligand-bound and -unbound crystal structures.

Authors : Dangi B; Department of Life Science and Biochemical Engineering, Sunmoon University, Asansi, Korea.; Lee CW

Subjects: Bacterial Proteins/Bacterial Proteins/Bacterial Proteins/*chemistry ; Steroid Hydroxylases/Steroid Hydroxylases/Steroid Hydroxylases/*chemistry ; Streptomyces/Streptomyces/Streptomyces/*enzymology

Source: The FEBS journal [FEBS J] 2019 May; Vol. 286 (9), pp. 1683-1699. Date of Electronic Publication: 2018 Dec 31.Publisher: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies Country of Publication: England NLM ID: 101229646 Publication

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Academic Journal

25-hydroxycholesterol promotes brain cytokine production and leukocyte infiltration in a mouse model of lipopolysaccharide-induced neuroinflammation.

Authors : Romero J; Department of Psychiatry, Washington University School of Medicine, St Louis, MO, 63110, USA.; Toral-Rios D

Subjects: Lipopolysaccharides*/Lipopolysaccharides*/Lipopolysaccharides*/toxicity ; Lipopolysaccharides*/Lipopolysaccharides*/Lipopolysaccharides*/pharmacology ; Hydroxycholesterols*/Hydroxycholesterols*/Hydroxycholesterols*/metabolism

Source: Journal of neuroinflammation [J Neuroinflammation] 2024 Oct 05; Vol. 21 (1), pp. 251. Date of Electronic Publication: 2024 Oct 05.Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094

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Academic Journal

An Unexpected Enzyme in Vascular Smooth Muscle Cells: Angiotensin II Upregulates Cholesterol-25-Hydroxylase Gene Expression.

Authors : Kovács KB; Department of Physiology, Semmelweis University, 1094 Budapest, Hungary.; Szalai L

Subjects: Angiotensin II*/Angiotensin II*/Angiotensin II*/metabolism ; Muscle, Smooth, Vascular*/Muscle, Smooth, Vascular*/Muscle, Smooth, Vascular*/enzymology ; Steroid Hydroxylases*/Steroid Hydroxylases*/Steroid Hydroxylases*/genetics

Source: International journal of molecular sciences [Int J Mol Sci] 2023 Feb 16; Vol. 24 (4). Date of Electronic Publication: 2023 Feb 16.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Role of Cholesterol 25-Hydroxylase (Ch25h) in Mediating Innate Immune Responses to Streptococcus pneumoniae Infection.

Authors : Cho SJ; Weill Cornell Medicine, New York, NY 10021, USA.; Pronko A

Subjects: Lung*/Lung*/Lung*/metabolism ; Pneumococcal Infections* ; Steroid Hydroxylases*

Source: Cells [Cells] 2023 Feb 10; Vol. 12 (4). Date of Electronic Publication: 2023 Feb 10.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

Modification of B-Nor Steroids Mediated by Filamentous Fungus Fusarium culmorum : Focus on 15α-Hydroxylase Activity.

Authors : Świzdor A; Department of Food Chemistry and Biocatalysis, Wrocław University of Environmental and Life Sciences, Norwida 25, 50-375 Wrocław, Poland.; Janeczko T

Subjects: Fusarium*/Fusarium*/Fusarium*/metabolism ; Fusarium*/Fusarium*/Fusarium*/enzymology ; Biotransformation*

Source: International journal of molecular sciences [Int J Mol Sci] 2024 Nov 06; Vol. 25 (22). Date of Electronic Publication: 2024 Nov 06.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

In Silico Prediction of the Metabolic Resistance of Vitamin D Analogs against CYP3A4 Metabolizing Enzyme.

Authors : Żołek T; Department of Organic Chemistry, Faculty of Pharmacy, Medical University of Warsaw, 1 Banacha, 02-097 Warsaw, Poland.; Yasuda K

Subjects: Steroid Hydroxylases*/Steroid Hydroxylases*/Steroid Hydroxylases*/metabolism ; Vitamin D*/Vitamin D*/Vitamin D*/metabolism; Cytochrome P-450 CYP3A

Source: International journal of molecular sciences [Int J Mol Sci] 2022 Jul 16; Vol. 23 (14). Date of Electronic Publication: 2022 Jul 16.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Bacterial steroid hydroxylases: enzyme classes, their functions and comparison of their catalytic mechanisms.

Authors : Szaleniec M; Jerzy Haber Institute of Catalysis and Surface Chemistry, Polish Academy of Sciences, Niezapominajek 8, 30-239, Kraków, Poland. .; Wojtkiewicz AM

Subjects: Bacterial Proteins/Bacterial Proteins/Bacterial Proteins/*metabolism ; Steroid Hydroxylases/Steroid Hydroxylases/Steroid Hydroxylases/*metabolism; Animals

Source: Applied microbiology and biotechnology [Appl Microbiol Biotechnol] 2018 Oct; Vol. 102 (19), pp. 8153-8171. Date of Electronic Publication: 2018 Jul 21.Publisher: Springer International Country of Publication: Germany NLM ID: 8406612 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Association of CYP7B1 expression with the prognosis of endometrial cancer: a retrospective study.

Authors : Lu XF; Department of Epidemiology, School of Medicine, Jinan University, No. 601, Huangpu Avenue West, Tianhe District, Guangzhou, 510632, China.; Huang T

Subjects: Endometrial Neoplasms*/Endometrial Neoplasms*/Endometrial Neoplasms*/pathology ; Endometrial Neoplasms*/Endometrial Neoplasms*/Endometrial Neoplasms*/metabolism ; Endometrial Neoplasms*/Endometrial Neoplasms*/Endometrial Neoplasms*/mortality

Source: World journal of surgical oncology [World J Surg Oncol] 2024 Sep 17; Vol. 22 (1), pp. 251. Date of Electronic Publication: 2024 Sep 17.Publisher: BioMed Central Country of Publication: England NLM ID: 101170544 Publication Model: Electronic Cited Medium: Internet ISSN: 1477-7819

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Academic Journal

Tumor Necrosis Factor-alpha utilizes MAPK/NFκB pathways to induce cholesterol-25 hydroxylase for amplifying pro-inflammatory response via 25-hydroxycholesterol-integrin-FAK pathway.

Authors : Pokharel SM; Department of Veterinary Microbiology and Pathology, College of Veterinary Medicine, Washington State University, Pullman, Washington, United States of America.; Chiok K

Subjects: Signal Transduction/Signal Transduction/Signal Transduction/*drug effects ; Steroid Hydroxylases/Steroid Hydroxylases/Steroid Hydroxylases/*metabolism ; Tumor Necrosis Factor-alpha/Tumor Necrosis Factor-alpha/Tumor Necrosis Factor-alpha/*pharmacology

Source: PloS one [PLoS One] 2021 Sep 22; Vol. 16 (9), pp. e0257576. Date of Electronic Publication: 2021 Sep 22 (Print Publication: 2021).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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فلترة النتائج

Cholesterol 25-Hydroxylase Protects Against Diabetic Kidney Disease by Regulating ADP Ribosylation Factor 4.

Characterization of two steroid hydroxylases from different Streptomyces spp. and their ligand-bound and -unbound crystal structures.

25-hydroxycholesterol promotes brain cytokine production and leukocyte infiltration in a mouse model of lipopolysaccharide-induced neuroinflammation.

An Unexpected Enzyme in Vascular Smooth Muscle Cells: Angiotensin II Upregulates Cholesterol-25-Hydroxylase Gene Expression.

Role of Cholesterol 25-Hydroxylase (Ch25h) in Mediating Innate Immune Responses to Streptococcus pneumoniae Infection.

Modification of B-Nor Steroids Mediated by Filamentous Fungus Fusarium culmorum : Focus on 15α-Hydroxylase Activity.

In Silico Prediction of the Metabolic Resistance of Vitamin D Analogs against CYP3A4 Metabolizing Enzyme.

Bacterial steroid hydroxylases: enzyme classes, their functions and comparison of their catalytic mechanisms.

Association of CYP7B1 expression with the prognosis of endometrial cancer: a retrospective study.

Tumor Necrosis Factor-alpha utilizes MAPK/NFκB pathways to induce cholesterol-25 hydroxylase for amplifying pro-inflammatory response via 25-hydroxycholesterol-integrin-FAK pathway.

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