نتائج البحث

Photosensitive and dual-targeted chromium nanoparticle delivering small interfering RNA YTHDF1 for molecular-targeted immunotherapy in liver cancer.

• Authors : Chen S; Department of Laboratory Medicine, Huazhong University of Science and Technology Union Shenzhen Hospital (Nanshan Hospital), Shenzhen University, Shenzhen, 518052, People's Republic of China.; Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, National-Regional Key Technology Engineering Laboratory for Medical Ultrasound, School of Biomedical Engineering, Shenzhen University Medical School, Shenzhen, 518060, People's Republic of China.

Subjects: Immunotherapy*/Immunotherapy*/Immunotherapy*/methods ; RNA, Small Interfering* ; Liver Neoplasms*/Liver Neoplasms*/Liver Neoplasms*/therapy

• Source: Journal of nanobiotechnology [J Nanobiotechnology] 2024 Jun 19; Vol. 22 (1), pp. 348. Date of Electronic Publication: 2024 Jun 19.Publisher: BioMed Central Country of Publication: England NLM ID: 101152208 Publication Model: Electronic Cited Medium: Internet ISSN: 1477-3155

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Cholesterol Conjugates of Small Interfering RNA: Linkers and Patterns of Modification.

• Authors : Chernikov IV; Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Academic Lavrentiev Avenue 8, 630090 Novosibirsk, Russia.; Ponomareva UA

Subjects: RNA, Double-Stranded* ; Cholesterol*; Humans

• Source: Molecules (Basel, Switzerland) [Molecules] 2024 Feb 08; Vol. 29 (4). Date of Electronic Publication: 2024 Feb 08.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Evaluation of on- and off-target effects of self-assembled epidermal growth factor receptor small interfering RNA delivery system.

• Authors : Guo H; Nanjing Drum Tower Hospital Center of Molecular Diagnostic and Therapy, State Key Laboratory of Pharmaceutical Biotechnology, Jiangsu Engineering Research Center for MicroRNA Biology and Biotechnology, NJU Advanced Institute of Life Sciences (NAILS), School of Life Sciences, Nanjing University, Nanjing, China.; Chemistry and Biomedicine Innovation Center (ChemBIC), Nanjing University, Nanjing, China.

Subjects: ErbB Receptors*/ErbB Receptors*/ErbB Receptors*/genetics ; ErbB Receptors*/ErbB Receptors*/ErbB Receptors*/metabolism; RNA, Small Interfering/RNA, Small Interfering/RNA, Small Interfering/genetics

• Source: Clinical and translational medicine [Clin Transl Med] 2024 Feb; Vol. 14 (2), pp. e1579.Publisher: Wiley Country of Publication: United States NLM ID: 101597971 Publication Model: Print Cited Medium: Internet ISSN: 2001-1326

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The Efficacy and Safety of Polyethylene Glycol Cholesterol- and Tocopherol Polyethylene Glycol 1000 Succinate-Modified Transforming Growth Factor β1 Small Interfering RNA Lipid Nanoparticles in the Treatment of Paclitaxel-Resistant Non-Small-Cell Lung Cancer.

• Authors : Zeng Z; School of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China.; Zeng X

• Source: Pharmaceutics [Pharmaceutics] 2024 Jan 04; Vol. 16 (1). Date of Electronic Publication: 2024 Jan 04.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101534003 Publication Model: Electronic Cited Medium: Print ISSN: 1999-4923 (Print)

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Molecular Therapies in Cardiovascular Diseases: Small Interfering RNA in Atherosclerosis, Heart Failure, and Hypertension.

• Authors : Sarzani R; Internal Medicine and Geriatrics, ESH 'Hypertension Excellence Centre', SISA LIPIGEN Centre, IRCCS INRCA, 60127 Ancona, Italy.; Department of Clinical and Molecular Sciences, University 'Politecnica delle Marche', 60126 Ancona, Italy.

Subjects: Cardiovascular Diseases*/Cardiovascular Diseases*/Cardiovascular Diseases*/genetics ; Cardiovascular Diseases*/Cardiovascular Diseases*/Cardiovascular Diseases*/therapy ; Heart Failure*/Heart Failure*/Heart Failure*/genetics

• Source: International journal of molecular sciences [Int J Mol Sci] 2023 Dec 26; Vol. 25 (1). Date of Electronic Publication: 2023 Dec 26.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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[Retracted] Inhibiting proliferation and migration of lung cancer using small interfering RNA targeting on Aldo‑keto reductase family 1 member B10.

• Authors : Zhou Z; Department of Lung Tumor Clinical Center, Shanghai Chest Hospital, Shanghai Jiaotong University, Shanghai 200030, P.R. China.; Zhao Y

• Source: Molecular medicine reports [Mol Med Rep] 2023 Nov; Vol. 28 (5). Date of Electronic Publication: 2023 Oct 06.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Small interfering RNA (siRNA)-based therapeutic applications against viruses: principles, potential, and challenges.

• Authors : Kang H; Department of Life Sciences, College of Life Sciences and Bioengineering, Incheon National University, Academy-Ro 119, Yeonsu-Gu, Incheon, 22012, South Korea.; Ga YJ

Subjects: COVID-19*/COVID-19*/COVID-19*/genetics ; COVID-19*/COVID-19*/COVID-19*/therapy ; Viruses*/Viruses*/Viruses*/genetics

• Source: Journal of biomedical science [J Biomed Sci] 2023 Oct 16; Vol. 30 (1), pp. 88. Date of Electronic Publication: 2023 Oct 16.Publisher: BioMed Central Country of Publication: England NLM ID: 9421567 Publication Model: Electronic Cited Medium: Internet ISSN: 1423-0127

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Proprotein convertase subtilisn/kexin type 9 inhibitors and small interfering RNA therapy for cardiovascular risk reduction: A systematic review and meta-analysis.

• Authors : Imran TF; Providence VA Medical Center, Providence, Rhode Island, United States of America.; Lifespan Cardiovascular Institute, Rhode Island and Miriam Hospitals, Providence, Rhode Island, United States of America.

Subjects: Myocardial Infarction*/Myocardial Infarction*/Myocardial Infarction*/drug therapy ; Atherosclerosis*/Atherosclerosis*/Atherosclerosis*/drug therapy ; Anticholesteremic Agents*/Anticholesteremic Agents*/Anticholesteremic Agents*/therapeutic use

• Source: PloS one [PLoS One] 2023 Dec 06; Vol. 18 (12), pp. e0295359. Date of Electronic Publication: 2023 Dec 06 (Print Publication: 2023).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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The N-Acetylgalactosamine-conjugated small interfering RNA inclisiran can be coadministered safely with atorvastatin in cynomolgus monkeys resulting in additive low-density lipoprotein cholesterol reductions.

• Authors : Lehoux D; Targanta Therapeutics Inc., Saint Laurent, Quebec, Canada.; Kallend D

Subjects: Anticholesteremic Agents*/Anticholesteremic Agents*/Anticholesteremic Agents*/adverse effects ; Hydroxymethylglutaryl-CoA Reductase Inhibitors*/Hydroxymethylglutaryl-CoA Reductase Inhibitors*/Hydroxymethylglutaryl-CoA Reductase Inhibitors*/therapeutic use; Animals

• Source: Pharmacology research & perspectives [Pharmacol Res Perspect] 2023 Apr; Vol. 11 (2), pp. e01080.Publisher: John Wiley & Sons Ltd, British Pharmacological Society and American Society for Pharmacology and Experimental Therapeutics Country of Publication: United States

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Inclisiran-Safety and Effectiveness of Small Interfering RNA in Inhibition of PCSK-9.

• Authors : Wołowiec Ł; Department of Cardiology and Clinical Pharmacology, Faculty of Health Sciences, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University, 87-100 Toruń, Poland.; Osiak J

• Source: Pharmaceutics [Pharmaceutics] 2023 Jan 18; Vol. 15 (2). Date of Electronic Publication: 2023 Jan 18.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101534003 Publication Model: Electronic Cited Medium: Print ISSN: 1999-4923 (Print)

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