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Academic Journal

Sphingosine 1-Phosphate Stimulates ER to Golgi Ceramide Traffic to Promote Survival in T98G Glioma Cells.

  • Authors : Giussani P; Department of Medical Biotechnology and Translational Medicine, Università degli Studi di Milano, LITA Segrate, Via Fratelli Cervi, 93, 20054 Segrate, Italy.; Brioschi L

Subjects: Lysophospholipids*/Lysophospholipids*/Lysophospholipids*/metabolism ; Lysophospholipids*/Lysophospholipids*/Lysophospholipids*/pharmacology ; Ceramides*/Ceramides*/Ceramides*/metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Jul 29; Vol. 25 (15). Date of Electronic Publication: 2024 Jul 29.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Sphingosine 1-phosphate receptor modulators in multiple sclerosis treatment: A practical review.

  • Authors : Coyle PK; Department of Neurology, Stony Brook Renaissance School of Medicine, Stony Brook University, Stony Brook, New York, USA.; Freedman MS

Subjects: Multiple Sclerosis*/Multiple Sclerosis*/Multiple Sclerosis*/drug therapy ; Sphingosine 1 Phosphate Receptor Modulators*/Sphingosine 1 Phosphate Receptor Modulators*/Sphingosine 1 Phosphate Receptor Modulators*/adverse effects; United States

  • Source: Annals of clinical and translational neurology [Ann Clin Transl Neurol] 2024 Apr; Vol. 11 (4), pp. 842-855. Date of Electronic Publication: 2024 Feb 16.Publisher: Wiley Periodicals, Inc on behalf of American Neurological Association Country of Publication: United States NLM ID: 101623278 Publication Model:

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Academic Journal

A Near-Infrared Fluorogenic Probe for Rapid, Specific, and Ultrasensitive Detection of Sphingosine in Living Cells and In Vivo.

  • Authors : Chen Y; State Key Laboratory of Coordination Chemistry, Chemistry and Biomedicine Innovation Center (ChemBIC), School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, 210023, China.; Hao T

Subjects: Sphingosine*/Sphingosine*/Sphingosine*/metabolism ; Sphingosine*/Sphingosine*/Sphingosine*/pharmacology ; Zebrafish*/Zebrafish*/Zebrafish*/metabolism

  • Source: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2024 Jan; Vol. 11 (2), pp. e2307598. Date of Electronic Publication: 2023 Nov 30.Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844

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Academic Journal

N -Acetylcysteine Alleviates Impaired Muscular Function Resulting from Sphingosine Phosphate Lyase Functional Deficiency-Induced Sphingoid Base and Ceramide Accumulation in Caenorhabditis elegans .

  • Authors : Liu M; Jiangxi Province Key Laboratory of Aging and Disease, Human Aging Research Institute (HARI), School of Life Science, Nanchang University, Nanchang 330031, China.; You Y

Subjects: Caenorhabditis elegans*/Caenorhabditis elegans*/Caenorhabditis elegans*/drug effects ; Acetylcysteine*/Acetylcysteine*/Acetylcysteine*/pharmacology ; Ceramides*/Ceramides*/Ceramides*/metabolism

  • Source: Nutrients [Nutrients] 2024 May 26; Vol. 16 (11). Date of Electronic Publication: 2024 May 26.Publisher: MDPI Publishing Country of Publication: Switzerland NLM ID: 101521595 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

AAV-SPL 2.0, a Modified Adeno-Associated Virus Gene Therapy Agent for the Treatment of Sphingosine Phosphate Lyase Insufficiency Syndrome.

  • Authors : Khan R; Department of Pediatrics, Division of Hematology/Oncology, University of California, San Francisco, CA 94143, USA.; Oskouian B

Subjects: Parvovirinae*/Parvovirinae*/Parvovirinae*/metabolism ; Sphingosine*/Sphingosine*/Sphingosine*/metabolism ; Genetic Therapy*Adeno-associated virus-2

  • Source: International journal of molecular sciences [Int J Mol Sci] 2023 Oct 25; Vol. 24 (21). Date of Electronic Publication: 2023 Oct 25.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Review article: the sphingosine 1 phosphate/sphingosine 1 phosphate receptor axis - a unique therapeutic target in inflammatory bowel disease.

  • Authors : Wang J; Henan Key Laboratory of Immunology and Targeted Drug, Xinxiang Medical University, Xinxiang, Henan Province, China.; Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA.

Subjects: Inflammatory Bowel Diseases*/Inflammatory Bowel Diseases*/Inflammatory Bowel Diseases*/drug therapy ; Sphingosine 1 Phosphate Receptor Modulators*/Sphingosine 1 Phosphate Receptor Modulators*/Sphingosine 1 Phosphate Receptor Modulators*/therapeutic use; Humans

  • Source: Alimentary pharmacology & therapeutics [Aliment Pharmacol Ther] 2022 Feb; Vol. 55 (3), pp. 277-291. Date of Electronic Publication: 2021 Dec 21.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 8707234 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Sphingosine Prevents Rhinoviral Infections.

  • Authors : Lang J; Department of Immunology, University Clinic, University of Duisburg-Essen, Hufelandstrasse 55, 45122 Essen, Germany.; Soddemann M

Subjects: Enterovirus Infections* ; Respiratory Tract Infections*; Humans

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Feb 20; Vol. 25 (5). Date of Electronic Publication: 2024 Feb 20.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Sphingosine 1-Phosphate Regulates Obesity and Glucose Homeostasis.

  • Authors : Kajita K; Department of Health and Nutrition, Faculty of Home Economics, Gifu Women's University, 80 Taromaru, Gifu 501-2592, Japan.; Ishii I

Subjects: Diabetes Mellitus, Type 2* ; Insulin Resistance* ; Lysophospholipids*

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Jan 11; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 11.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Sphingoid Bases Regulate the Sigma-1 Receptor-Sphingosine and N , N '-Dimethylsphingosine Are Endogenous Agonists.

  • Authors : Li J; Department of Surgery, School of Medicine, University of Virginia, Charlottesville, VA 22908, USA.; Satyshur KA

Subjects: Sphingosine* ; Receptors, sigma*; Animals

  • Source: International journal of molecular sciences [Int J Mol Sci] 2023 Feb 04; Vol. 24 (4). Date of Electronic Publication: 2023 Feb 04.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

miR-495 promotes intestinal epithelial cell apoptosis through downregulation of Sphingosine-1-phosphate.

  • Authors : Li R; Baltimore Veterans Affairs Medical Center, Baltimore, Maryland, USA.; Department of Surgery, Cell Biology Group, University of Maryland School of Medicine, Baltimore, Maryland, USA.

Subjects: MicroRNAs*/MicroRNAs*/MicroRNAs*/metabolism ; MicroRNAs*/MicroRNAs*/MicroRNAs*/genetics ; Lysophospholipids*/Lysophospholipids*/Lysophospholipids*/metabolism

  • Source: Physiological reports [Physiol Rep] 2024 Sep; Vol. 12 (17), pp. e70021.Publisher: published by Wiley Periodicals, Inc. on behalf of the American Physiological Society and The Physiological Society Country of Publication: United States NLM

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