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Academic Journal

Identification of SARS-CoV-2 Papain-like Protease (PLpro) Inhibitors Using Combined Computational Approach.

  • Authors : Sencanski M; Laboratory of Bioinformatics and Computational Chemistry Institute of Nuclear Sciences Vinca National Institute of the Republic of Serbia, University of Belgrade, Mike Petrovica Alasa 12-14, 11000, Belgrade, Serbia.; Perovic V

Subjects: Coronavirus Papain-Like Proteases/Coronavirus Papain-Like Proteases/Coronavirus Papain-Like Proteases/*chemistry ; SARS-CoV-2/SARS-CoV-2/SARS-CoV-2/*chemistry; COVID-19

  • Source: ChemistryOpen [ChemistryOpen] 2022 Feb; Vol. 11 (2), pp. e202100248.Publisher: Wiley-VCH Verlag Country of Publication: Germany NLM ID: 101594811 Publication Model: Print Cited Medium: Internet ISSN: 2191-1363

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Academic Journal

Beyond the vaccines: a glance at the small molecule and peptide-based anti-COVID19 arsenal.

  • Authors : Nepali K; School of Pharmacy, College of Pharmacy, Taipei Medical University, 250 Wuxing Street, Taipei, 11031, Taiwan.; TMU Research Center for Drug Discovery, Taipei Medical University, Taipei, 11031, Taiwan.

Subjects: COVID-19*/COVID-19*/COVID-19*/prevention & control ; Vaccines* ; COVID-19 Drug Treatment*SARS-CoV-2 variants

  • Source: Journal of biomedical science [J Biomed Sci] 2022 Sep 06; Vol. 29 (1), pp. 65. Date of Electronic Publication: 2022 Sep 06.Publisher: BioMed Central Country of Publication: England NLM ID: 9421567 Publication Model: Electronic Cited Medium: Internet ISSN: 1423-0127

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Academic Journal

An ISG15-Based High-Throughput Screening Assay for Identification and Characterization of SARS-CoV-2 Inhibitors Targeting Papain-like Protease.

  • Authors : Samrat SK; Department of Pharmacology and Toxicology, R Ken Coit College of Pharmacy, The University of Arizona, 1703 E Mabel St, Tucson, AZ 85721, USA.; Kumar P

Subjects: SARS-CoV-2*/SARS-CoV-2*/SARS-CoV-2*/drug effects ; SARS-CoV-2*/SARS-CoV-2*/SARS-CoV-2*/enzymology ; Antiviral Agents*/Antiviral Agents*/Antiviral Agents*/pharmacology

  • Source: Viruses [Viruses] 2024 Aug 01; Vol. 16 (8). Date of Electronic Publication: 2024 Aug 01.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915

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Academic Journal

Natural-Target-Mimicking Translocation-Based Fluorescent Sensor for Detection of SARS-CoV-2 PLpro Protease Activity and Virus Infection in Living Cells.

  • Authors : Sokolinskaya EL; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Miklukho-Maklaya 16/10, 117997 Moscow, Russia.; Ivanova ON

Subjects: SARS-CoV-2*/SARS-CoV-2*/SARS-CoV-2*/metabolism ; COVID-19*/COVID-19*/COVID-19*/virology ; COVID-19*/COVID-19*/COVID-19*/diagnosis

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Jun 17; Vol. 25 (12). Date of Electronic Publication: 2024 Jun 17.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

In Situ Endothelial SARS-CoV-2 Presence and PROS1 Plasma Levels Alteration in SARS-CoV-2-Associated Coagulopathies.

  • Authors : Baroni M; Department of Life Sciences and Biotechnology (SVEB), University of Ferrara, 44121 Ferrara, Italy.; Beltrami S

  • Source: Life (Basel, Switzerland) [Life (Basel)] 2024 Feb 08; Vol. 14 (2). Date of Electronic Publication: 2024 Feb 08.Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101580444 Publication Model: Electronic Cited Medium: Print ISSN: 2075-1729

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Academic Journal

Combining computational and experimental evidence on the activity of antimalarial drugs on papain-like protease of SARS-CoV-2: A repurposing study.

  • Authors : Ribaudo G; Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.; Yun X

Subjects: Antimalarials* ; COVID-19*; Humans

  • Source: Chemical biology & drug design [Chem Biol Drug Des] 2023 Apr; Vol. 101 (4), pp. 809-818. Date of Electronic Publication: 2022 Dec 14.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101262549 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

A Review of In Silico Research, SARS-CoV-2, and Neurodegeneration: Focus on Papain-Like Protease.

  • Authors : Rieder AS; Laboratory of Neuroprotection and Neurometabolic Diseases, Wyse's Lab, Department of Biochemistry, ICBS, Universidade Federal Do Rio Grande Do Sul (UFRGS), Rua Ramiro Barcelos, 2600-Anexo, Porto Alegre, RS, 90035-003, Brazil.; Deniz BF

Subjects: Curcumin* ; COVID-19 Drug Treatment*; Glycyrrhizic Acid

  • Source: Neurotoxicity research [Neurotox Res] 2022 Oct; Vol. 40 (5), pp. 1553-1569. Date of Electronic Publication: 2022 Aug 02.Publisher: Springer Country of Publication: United States NLM ID: 100929017 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Discovery of the Cryptic Sites of SARS-CoV-2 Papain-like Protease and Analysis of Its Druggability.

  • Authors : Qiu Y; Dr. Neher's Biophysics Laboratory for Innovative Drug Discovery, State Key Laboratory of Quality Research in Chinese Medicine, Macau Institute for Applied Research in Medicine and Health, Macau University of Science and Technology, Taipa, Macau, China.; Liu Q

Subjects: Papain*/Papain*/Papain*/metabolism ; COVID-19 Drug Treatment*; Amino Acid Sequence

  • Source: International journal of molecular sciences [Int J Mol Sci] 2022 Sep 24; Vol. 23 (19). Date of Electronic Publication: 2022 Sep 24.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Genetically Encoded Fluorescent Sensors for SARS-CoV-2 Papain-like Protease PLpro.

  • Authors : Sokolinskaya EL; Center for Molecular and Cellular Biology, Skolkovo Institute of Science and Technology, Bolshoy Blvd 30, bld. 1, 121205 Moscow, Russia.; Putlyaeva LV

Subjects: COVID-19* ; SARS-CoV-2*/SARS-CoV-2*/SARS-CoV-2*/genetics; Coronavirus Papain-Like Proteases

  • Source: International journal of molecular sciences [Int J Mol Sci] 2022 Jul 15; Vol. 23 (14). Date of Electronic Publication: 2022 Jul 15.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Unraveling the unbinding pathways of SARS-CoV-2 Papain-like proteinase known inhibitors by Supervised Molecular Dynamics simulation.

  • Authors : Sohraby F; Department of Biology, Faculty of Science, Golestan University, Gorgan, Iran.; Aryapour H

Subjects: COVID-19 Drug Treatment*; Coronavirus Papain-Like Proteases/Coronavirus Papain-Like Proteases/Coronavirus Papain-Like Proteases/*antagonists & inhibitors ; Protease Inhibitors/Protease Inhibitors/Protease Inhibitors/*pharmacology

  • Source: PloS one [PLoS One] 2021 May 19; Vol. 16 (5), pp. e0251910. Date of Electronic Publication: 2021 May 19 (Print Publication: 2021).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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