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Academic Journal

Diversity of mechanisms to control bacterial GTP homeostasis by the mutually exclusive binding of adenine and guanine nucleotides to IMP dehydrogenase.

Subjects: Guanine Nucleotides* ; IMP Dehydrogenase*/IMP Dehydrogenase*/IMP Dehydrogenase*/genetics ; IMP Dehydrogenase*/IMP Dehydrogenase*/IMP Dehydrogenase*/metabolism

  • Source: Protein science : a publication of the Protein Society [Protein Sci] 2022 May; Vol. 31 (5), pp. e4314.Publisher: Cold Spring Harbor Laboratory Press Country of Publication: United States NLM ID: 9211750 Publication Model: Print Cited Medium: Internet

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Academic Journal

IMPDH Inhibition Decreases TERT Expression and Synergizes the Cytotoxic Effect of Chemotherapeutic Agents in Glioblastoma Cells.

  • Authors : Liu X; Institute of Biosciences and Technology, Texas A&M University Health Science Center, Houston, TX 77030, USA.; Wang J

Subjects: Telomerase*/Telomerase*/Telomerase*/metabolism ; Telomerase*/Telomerase*/Telomerase*/antagonists & inhibitors ; Telomerase*/Telomerase*/Telomerase*/genetics

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 May 30; Vol. 25 (11). Date of Electronic Publication: 2024 May 30.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Insight into the role of the Bateman domain at the molecular and physiological levels through engineered IMP dehydrogenases.

  • Authors : Gedeon A; Institut Pasteur, Université Paris Cité, Unité de Chimie et Biocatalyse, CNRS UMR3523, Paris, France.; Ayoub N

Subjects: IMP Dehydrogenase*/IMP Dehydrogenase*/IMP Dehydrogenase*/genetics ; IMP Dehydrogenase*/IMP Dehydrogenase*/IMP Dehydrogenase*/metabolism ; Adenosine Triphosphate*

  • Source: Protein science : a publication of the Protein Society [Protein Sci] 2023 Aug; Vol. 32 (8), pp. e4703.Publisher: Cold Spring Harbor Laboratory Press Country of Publication: United States NLM ID: 9211750 Publication Model: Print Cited Medium: Internet

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Academic Journal

IMP dehydrogenase rod/ring structures in acral melanomas.

  • Authors : Keppeke GD; Rheumatology Division, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil.; Barcelos D

Subjects: IMP Dehydrogenase/IMP Dehydrogenase/IMP Dehydrogenase/*metabolism ; Melanoma/Melanoma/Melanoma/*enzymology ; Melanoma/Melanoma/Melanoma/*pathology

  • Source: Pigment cell & melanoma research [Pigment Cell Melanoma Res] 2020 May; Vol. 33 (3), pp. 490-497. Date of Electronic Publication: 2020 Jan 13.Publisher: Blackwell Munksgaard Country of Publication: England NLM ID: 101318927 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Mycophenolate Mofetil, an Inhibitor of Inosine Monophosphate Dehydrogenase, and Tofacitinib, a Janus Kinase Inhibitor, Attenuate Airway Inflammation and Hyperresponsiveness in a Mouse Model of Allergic Asthma.

  • Authors : Kravčenia B; Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego Street 13, 10-719 Olsztyn, Poland.; Maślanka T

Subjects: Asthma*/Asthma*/Asthma*/drug therapy ; Disease Models, Animal* ; Piperidines*/Piperidines*/Piperidines*/pharmacology

  • Source: Molecules (Basel, Switzerland) [Molecules] 2024 Nov 09; Vol. 29 (22). Date of Electronic Publication: 2024 Nov 09.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

The gateway to guanine nucleotides: Allosteric regulation of IMP dehydrogenases.

  • Authors : Buey RM; Metabolic Engineering Group, Department of Microbiology and Genetics, Universidad de Salamanca, Salamanca, Spain.; Fernández-Justel D

Subjects: Guanine Nucleotides* ; IMP Dehydrogenase*/IMP Dehydrogenase*/IMP Dehydrogenase*/genetics ; IMP Dehydrogenase*/IMP Dehydrogenase*/IMP Dehydrogenase*/metabolism

  • Source: Protein science : a publication of the Protein Society [Protein Sci] 2022 Sep; Vol. 31 (9), pp. e4399.Publisher: Cold Spring Harbor Laboratory Press Country of Publication: United States NLM ID: 9211750 Publication Model: Print Cited Medium: Internet

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Academic Journal

c-Myc-IMPDH1/2 axis promotes tumourigenesis by regulating GTP metabolic reprogramming.

  • Authors : Zhang Q; The Sixth Affiliated Hospital, School of Medicine, Sun Yat-sen University, Guangzhou, Guangdong, China.; Cui K

Subjects: Carcinogenesis*/Carcinogenesis*/Carcinogenesis*/genetics ; IMP Dehydrogenase*/IMP Dehydrogenase*/IMP Dehydrogenase*/genetics ; Proto-Oncogene Proteins c-myc*/Proto-Oncogene Proteins c-myc*/Proto-Oncogene Proteins c-myc*/genetics

  • Source: Clinical and translational medicine [Clin Transl Med] 2023 Jan; Vol. 13 (1), pp. e1164.Publisher: Wiley Country of Publication: United States NLM ID: 101597971 Publication Model: Print Cited Medium: Internet ISSN: 2001-1326

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Academic Journal

Mutants of Helicobacter pylori IMPDH: Kinetics and in silico Studies to Determine the Structural and Functional Role of Key Amino Acids.

  • Authors : Dilip H; Discipline of Chemistry, Indian Institute of Technology Gandhinagar, Palaj Village, Gandhinagar, Gujarat 382055, India.; Purushothaman G

Subjects: Helicobacter pylori*/Helicobacter pylori*/Helicobacter pylori*/metabolism ; IMP Dehydrogenase*/IMP Dehydrogenase*/IMP Dehydrogenase*/genetics ; IMP Dehydrogenase*/IMP Dehydrogenase*/IMP Dehydrogenase*/metabolism

  • Source: Chemistry, an Asian journal [Chem Asian J] 2022 May 02; Vol. 17 (9), pp. e202200125. Date of Electronic Publication: 2022 Mar 29.Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101294643 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1861-471X

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Academic Journal

Inosine monophosphate dehydrogenase type1 sustains tumor growth in hepatocellular carcinoma.

  • Authors : Jia X; College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou, China.; Liu Y

Subjects: Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/genetics ; IMP Dehydrogenase*/IMP Dehydrogenase*/IMP Dehydrogenase*/genetics ; IMP Dehydrogenase*/IMP Dehydrogenase*/IMP Dehydrogenase*/metabolism

  • Source: Journal of clinical laboratory analysis [J Clin Lab Anal] 2022 May; Vol. 36 (5), pp. e24416. Date of Electronic Publication: 2022 Apr 11.Publisher: Wiley Country of Publication: United States NLM ID: 8801384 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-2825

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Academic Journal

Anfractuous assemblies of IMP dehydrogenase and CTP synthase: new twists on regulation?

  • Authors : McCluskey GD; Department of Biochemistry & Molecular Biology, Dalhousie University, Halifax, Canada.; Bearne SL

Subjects: Carbon-Nitrogen Ligases*; IMP Dehydrogenase/IMP Dehydrogenase/IMP Dehydrogenase/*antagonists & inhibitors; Cell Line

  • Source: The FEBS journal [FEBS J] 2018 Oct; Vol. 285 (20), pp. 3724-3728. Date of Electronic Publication: 2018 Oct 04.Publisher: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies Country of Publication: England NLM ID: 101229646 Publication

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