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Academic Journal

Bioequivalence of rimegepant, a small molecule CGRP receptor antagonist, administered as an oral tablet, a sublingual orally disintegrating tablet, and a supralingual orally disintegrating tablet: two phase 1 randomized studies in healthy adults.

Authors : Croop R; Biohaven Pharmaceuticals, New Haven, CT, USA.; Bhardwaj R

Subjects: Calcitonin Gene-Related Peptide Receptor Antagonists* ; Piperidines* ; Pyridines*

Source: Cephalalgia : an international journal of headache [Cephalalgia] 2024 Feb; Vol. 44 (2), pp. 3331024231219505.Publisher: Country of Publication: England NLM ID: 8200710 Publication Model: Print Cited Medium: Internet ISSN: 1468-2982 (Electronic)

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Academic Journal

CGRP receptor antagonist MK-8825 attenuates cortical spreading depression induced pain behavior.

Authors : Filiz A; 1 Department of Neurology and Algology, Gazi University Medical School, Besevler, Ankara, Turkey.; Tepe N

Subjects: Calcitonin Gene-Related Peptide Receptor Antagonists/Calcitonin Gene-Related Peptide Receptor Antagonists/Calcitonin Gene-Related Peptide Receptor Antagonists/*therapeutic use ; Cortical Spreading Depression/Cortical Spreading Depression/Cortical Spreading Depression/*drug effects ; Pain/Pain/Pain/*drug therapy

Source: Cephalalgia : an international journal of headache [Cephalalgia] 2019 Mar; Vol. 39 (3), pp. 354-365. Date of Electronic Publication: 2017 Oct 03.Publisher: Country of Publication: England NLM ID: 8200710 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1468-2982

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Academic Journal

CGRP receptor antagonist activity of olcegepant depends on the signalling pathway measured.

Authors : Walker CS; 1 School of Biological Sciences, University of Auckland, Auckland, New Zealand.; 2 Centre for Brain Research, University of Auckland, Auckland, New Zealand.

Subjects: Calcitonin Gene-Related Peptide Receptor Antagonists/Calcitonin Gene-Related Peptide Receptor Antagonists/Calcitonin Gene-Related Peptide Receptor Antagonists/*pharmacology ; Dipeptides/Dipeptides/Dipeptides/*pharmacology ; Neurons/Neurons/Neurons/*drug effects

Source: Cephalalgia : an international journal of headache [Cephalalgia] 2018 Mar; Vol. 38 (3), pp. 437-451. Date of Electronic Publication: 2017 Feb 06.Publisher: Country of Publication: England NLM ID: 8200710 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1468-2982

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Academic Journal

Randomized controlled trial of the CGRP receptor antagonist telcagepant for prevention of headache in women with perimenstrual migraine.

Authors : Ho TW; Merck & Co. Inc, Department of Clinical Research, USA.; Ho AP

Subjects: Azepines/Azepines/Azepines/*therapeutic use ; Imidazoles/Imidazoles/Imidazoles/*therapeutic use ; Migraine Disorders/Migraine Disorders/Migraine Disorders/*prevention & control

Source: Cephalalgia : an international journal of headache [Cephalalgia] 2016 Feb; Vol. 36 (2), pp. 148-61. Date of Electronic Publication: 2015 Apr 29.Publisher: Country of Publication: England NLM ID: 8200710 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1468-2982

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Academic Journal

The novel CGRP receptor antagonist BIBN4096BS alleviates a postoperative intestinal inflammation and prevents postoperative ileus.

Authors : Glowka TR; Department of Surgery, University of Bonn, Bonn, Germany.; Steinebach A

Subjects: Ileus/Ileus/Ileus/*prevention & control ; Inflammation/Inflammation/Inflammation/*drug therapy ; Intestines/Intestines/Intestines/*drug effects

Source: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society [Neurogastroenterol Motil] 2015 Jul; Vol. 27 (7), pp. 1038-49. Date of Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 9432572 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Lack of hemodynamic interaction between CGRP-receptor antagonist telcagepant (MK-0974) and sumatriptan: results from a randomized study in patients with migraine.

Authors : Depré M; Center for Clinical Pharmacology, University Hospitals Leuven, Belgium.; Macleod C

Subjects: Analgesics/Analgesics/Analgesics/*administration & dosage ; Azepines/Azepines/Azepines/*administration & dosage ; Blood Pressure/Blood Pressure/Blood Pressure/*drug effects

Source: Cephalalgia : an international journal of headache [Cephalalgia] 2013 Dec; Vol. 33 (16), pp. 1292-301. Date of Electronic Publication: 2013 Jun 24.Publisher: Country of Publication: England NLM ID: 8200710 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1468-2982

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Academic Journal

Randomized controlled trial of the CGRP receptor antagonist MK-3207 in the acute treatment of migraine.

Authors : Hewitt DJ; Merck & Co. Inc., North Wales, PA 19454-1099, USA. ; Aurora SK

Subjects: Calcitonin Gene-Related Peptide Receptor Antagonists*; Bridged Bicyclo Compounds, Heterocyclic/Bridged Bicyclo Compounds, Heterocyclic/Bridged Bicyclo Compounds, Heterocyclic/*administration & dosage ; Migraine Disorders/Migraine Disorders/Migraine Disorders/*drug therapy

Source: Cephalalgia : an international journal of headache [Cephalalgia] 2011 Apr; Vol. 31 (6), pp. 712-22. Date of Electronic Publication: 2011 Mar 07.Publisher: Country of Publication: England NLM ID: 8200710 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1468-2982

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Academic Journal

Sustained pain freedom and no adverse events as an endpoint in clinical trials of acute migraine treatments: application to patient-level data from a trial of the CGRP receptor antagonist, telcagepant, and zolmitriptan.

Authors : Dodick DW; Department of Neurology, Mayo Clinic Arizona, 5777 E. Mayo Blvd., Phoenix, AZ 85054, USA. ; Kost J

Subjects: Calcitonin Gene-Related Peptide Receptor Antagonists* ; Research Design*; Analgesics/Analgesics/Analgesics/*adverse effects

Source: Cephalalgia : an international journal of headache [Cephalalgia] 2011 Feb; Vol. 31 (3), pp. 296-300. Date of Electronic Publication: 2010 Oct 11.Publisher: Country of Publication: England NLM ID: 8200710 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1468-2982

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Academic Journal

CGRP receptor antagonist olcegepant (BIBN4096BS) does not prevent glyceryl trinitrate-induced migraine.

Authors : Tvedskov JF; Department of Neurology, Danish Headache Center, Denmark. ; Tfelt-Hansen P

Subjects: Calcitonin Gene-Related Peptide Receptor Antagonists*; Dipeptides/Dipeptides/Dipeptides/*pharmacology ; Migraine Disorders/Migraine Disorders/Migraine Disorders/*drug therapy

Source: Cephalalgia : an international journal of headache [Cephalalgia] 2010 Nov; Vol. 30 (11), pp. 1346-53. Date of Electronic Publication: 2010 Apr 07.Publisher: Country of Publication: England NLM ID: 8200710 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1468-2982

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Academic Journal

Effect of the calcitonin gene-related peptide (CGRP) receptor antagonist telcagepant in human cranial arteries.

Authors : Edvinsson L; Department of Internal Medicine, Lund University Hospital, Lund, Sweden. ; Chan KY

Subjects: Calcitonin Gene-Related Peptide Receptor Antagonists*; Azepines/Azepines/Azepines/*pharmacology ; Imidazoles/Imidazoles/Imidazoles/*pharmacology

Source: Cephalalgia : an international journal of headache [Cephalalgia] 2010 Oct; Vol. 30 (10), pp. 1233-40. Date of Electronic Publication: 2010 Mar 26.Publisher: Country of Publication: England NLM ID: 8200710 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1468-2982

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فلترة النتائج

Bioequivalence of rimegepant, a small molecule CGRP receptor antagonist, administered as an oral tablet, a sublingual orally disintegrating tablet, and a supralingual orally disintegrating tablet: two phase 1 randomized studies in healthy adults.

CGRP receptor antagonist MK-8825 attenuates cortical spreading depression induced pain behavior.

CGRP receptor antagonist activity of olcegepant depends on the signalling pathway measured.

Randomized controlled trial of the CGRP receptor antagonist telcagepant for prevention of headache in women with perimenstrual migraine.

The novel CGRP receptor antagonist BIBN4096BS alleviates a postoperative intestinal inflammation and prevents postoperative ileus.

Lack of hemodynamic interaction between CGRP-receptor antagonist telcagepant (MK-0974) and sumatriptan: results from a randomized study in patients with migraine.

Randomized controlled trial of the CGRP receptor antagonist MK-3207 in the acute treatment of migraine.

Sustained pain freedom and no adverse events as an endpoint in clinical trials of acute migraine treatments: application to patient-level data from a trial of the CGRP receptor antagonist, telcagepant, and zolmitriptan.

CGRP receptor antagonist olcegepant (BIBN4096BS) does not prevent glyceryl trinitrate-induced migraine.

Effect of the calcitonin gene-related peptide (CGRP) receptor antagonist telcagepant in human cranial arteries.

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