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Content Provider : MEDLINE Subject : crispr-cas systems فلترة بواسطة : كلمات مفتاحية
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Academic Journal

Modulation of the microhomology-mediated end joining pathway suppresses large deletions and enhances homology-directed repair following CRISPR-Cas9-induced DNA breaks.

  • Authors : Yuan B; Bioscience Program, Biological and Environmental Science and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955-6900, Kingdom of Saudi Arabia.; Bi C

Subjects: CRISPR-Cas Systems* ; DNA End-Joining Repair* ; Gene Editing*/Gene Editing*/Gene Editing*/methods

  • Source: BMC biology [BMC Biol] 2024 Apr 29; Vol. 22 (1), pp. 101. Date of Electronic Publication: 2024 Apr 29.Publisher: BioMed Central Country of Publication: England NLM ID: 101190720 Publication Model: Electronic Cited Medium: Internet ISSN: 1741-7007

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Academic Journal

Fusion of histone variants to Cas9 suppresses non-homologous end joining.

  • Authors : Kato-Inui T; Tokyo Metropolitan Institute of Medical Science, Regenerative Medicine Project, Tokyo, Japan.; Takahashi G

Subjects: Histones*/Histones*/Histones*/metabolism ; Histones*/Histones*/Histones*/genetics ; DNA End-Joining Repair*

  • Source: PloS one [PLoS One] 2024 May 13; Vol. 19 (5), pp. e0288578. Date of Electronic Publication: 2024 May 13 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Proximal binding of dCas9 at a DNA double strand break stimulates homology-directed repair as a local inhibitor of classical non-homologous end joining.

  • Authors : Feng YL; Innovation Center for Minimally Invasive Technique and Device, Department of General Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310019, P.R. China.; Institute of Translational Medicine, Zhejiang University School of Medicine and Zhejiang University Cancer Center, Hangzhou, Zhejiang 310029, P.R. China.

Subjects: DNA Breaks, Double-Stranded* ; CRISPR-Cas Systems*; Animals

  • Source: Nucleic acids research [Nucleic Acids Res] 2023 Apr 11; Vol. 51 (6), pp. 2740-2758.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Characterization of sequence contexts that favor alternative end joining at Cas9-induced double-strand breaks.

  • Authors : Hanscom T; Department of Biology, Tufts University, 200 Boston Avenue, Suite 4700, Medford, MA 02155, USA.; Woodward N

Subjects: CRISPR-Cas Systems* ; DNA Breaks, Double-Stranded* ; DNA End-Joining Repair*

  • Source: Nucleic acids research [Nucleic Acids Res] 2022 Jul 22; Vol. 50 (13), pp. 7465-7478.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Current Strategies for Increasing Knock-In Efficiency in CRISPR/Cas9-Based Approaches.

  • Authors : Leal AF; Nemours Children's Health, Wilmington, DE 19803, USA.; Institute for the Study of Inborn Errors of Metabolism, Faculty of Science, Pontificia Universidad Javeriana, Bogotá 110231, Colombia.

Subjects: CRISPR-Cas Systems* ; Recombinational DNA Repair*; Animals

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Feb 20; Vol. 25 (5). Date of Electronic Publication: 2024 Feb 20.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Fusing an exonuclease with Cas9 enhances homologous recombination in Pichia pastoris.

  • Authors : Zhang K; Division of Biotechnology, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China.; Henan Engineering Laboratory for Bioconversion Technology of Functional Microbes, College of Life Sciences, Henan Normal University, Xinxiang, 453007, Henan, China.

Subjects: CRISPR-Cas Systems* ; DNA End-Joining Repair*; Coenzyme A Ligases Komagataella pastoris

  • Source: Microbial cell factories [Microb Cell Fact] 2022 Sep 07; Vol. 21 (1), pp. 182. Date of Electronic Publication: 2022 Sep 07.Publisher: BioMed Central Country of Publication: England NLM ID: 101139812 Publication Model: Electronic Cited Medium: Internet ISSN: 1475-2859

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Academic Journal

Efficient CRISPR/Cas9-based plant genomic fragment deletions by microhomology-mediated end joining.

  • Authors : Tan J; State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Guangzhou, China.; Guangdong Laboratory for Lingnan Modern Agriculture, Guangzhou, China.

Subjects: CRISPR-Cas Systems*/CRISPR-Cas Systems*/CRISPR-Cas Systems*/genetics ; Clustered Regularly Interspaced Short Palindromic Repeats*; DNA End-Joining Repair

  • Source: Plant biotechnology journal [Plant Biotechnol J] 2020 Nov; Vol. 18 (11), pp. 2161-2163. Date of Electronic Publication: 2020 May 22.Publisher: Wiley on behalf of the Society for Experimental Biology, Association of Applied Biologists Country of Publication: England NLM ID: 101201889 Publication

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Academic Journal

Long-read sequence analysis of MMEJ-mediated CRISPR genome editing reveals complex on-target vector insertions that may escape standard PCR-based quality control.

  • Authors : Higashitani Y; Department of Physiology II, Nara Medical University, Kashihara, Nara, 634-8521, Japan.; Horie K

Subjects: Gene Editing* ; CRISPR-Cas Systems*; Animals

  • Source: Scientific reports [Sci Rep] 2023 Jul 19; Vol. 13 (1), pp. 11652. Date of Electronic Publication: 2023 Jul 19.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Genome-scale CRISPR screens are efficient in non-homologous end-joining deficient cells.

  • Authors : Ferreira da Silva J; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Lazarettgasse 14, AKH BT 25.3, 1090, Vienna, Austria.; Salic S

Subjects: CRISPR-Cas Systems/CRISPR-Cas Systems/CRISPR-Cas Systems/*genetics ; Gene Editing/Gene Editing/Gene Editing/*methods; CRISPR-Associated Protein 9/CRISPR-Associated Protein 9/CRISPR-Associated Protein 9/metabolism

  • Source: Scientific reports [Sci Rep] 2019 Oct 31; Vol. 9 (1), pp. 15751. Date of Electronic Publication: 2019 Oct 31.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

A Multifunctional and Highly Adaptable Reporter System for CRISPR/Cas Editing.

  • Authors : Wettengel JM; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, OR 97006, USA.; Institute of Virology, Technical University of Munich/Helmholtz Zentrum München, 81675 München, Germany.

Subjects: CRISPR-Cas Systems*/CRISPR-Cas Systems*/CRISPR-Cas Systems*/genetics ; DNA Breaks, Double-Stranded*; Gene Editing

  • Source: International journal of molecular sciences [Int J Mol Sci] 2023 May 05; Vol. 24 (9). Date of Electronic Publication: 2023 May 05.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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  • 1-10 of  123 نتائج ل ""joining""