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Content Provider : MEDLINE Subject : b-lymphocytes Subject : translocation, genetic فلترة بواسطة : موضوع
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Academic Journal

DSB structure impacts DNA recombination leading to class switching and chromosomal translocations in human B cells.

  • Authors : So CC; Department of Immunology, University of Toronto, Toronto, Ontario, Canada.; Martin A

Subjects: DNA Breaks, Double-Stranded* ; Immunoglobulin Class Switching* ; Translocation, Genetic*

  • Source: PLoS genetics [PLoS Genet] 2019 Apr 04; Vol. 15 (4), pp. e1008101. Date of Electronic Publication: 2019 Apr 04 (Print Publication: 2019).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Tp53 deletion in B lineage cells predisposes mice to lymphomas with oncogenic translocations.

  • Authors : Rowh MA; Immunology Graduate Group, University of Pennsylvania School of Medicine, Philadelphia, PA, USA.; DeMicco A

Subjects: Cell Lineage* ; Translocation, Genetic*; B-Lymphocytes/B-Lymphocytes/B-Lymphocytes/*immunology

  • Source: Oncogene [Oncogene] 2011 Nov 24; Vol. 30 (47), pp. 4757-64. Date of Electronic Publication: 2011 May 30.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Genetic interaction between the non-homologous end-joining factors during B and T lymphocyte development: In vivo mouse models.

  • Authors : Castañeda-Zegarra S; Department of Clinical and Molecular Medicine (IKOM), Norwegian University of Science and Technology, Trondheim, Norway.; St. Olavs Hospital, Clinic of Medicine, Trondheim University Hospital, Trondheim, Norway.

Subjects: B-Lymphocytes/B-Lymphocytes/B-Lymphocytes/*immunology ; DNA End-Joining Repair/DNA End-Joining Repair/DNA End-Joining Repair/*immunology ; Immunoglobulin Class Switching/Immunoglobulin Class Switching/Immunoglobulin Class Switching/*immunology

  • Source: Scandinavian journal of immunology [Scand J Immunol] 2020 Oct; Vol. 92 (4), pp. e12936.Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 0323767 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

STAT3 imparts BRCAness by impairing homologous recombination repair in Epstein-Barr virus-transformed B lymphocytes.

  • Authors : McIntosh MT; Child Health Research Institute, Department of Pediatrics, University of Florida, Gainesville, FL, United States of America.; Department of Molecular Genetics and Microbiology, University of Florida, Gainesville, FL, United States of America.

Subjects: DNA Breaks, Double-Stranded* ; Recombinational DNA Repair*; B-Lymphocytes/B-Lymphocytes/B-Lymphocytes/*virology

  • Source: PLoS pathogens [PLoS Pathog] 2020 Oct 01; Vol. 16 (10), pp. e1008849. Date of Electronic Publication: 2020 Oct 01 (Print Publication: 2020).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Canonical non-homologous end-joining promotes genome mutagenesis and translocations induced by transcription-associated DNA topoisomerase 2 activity.

  • Authors : Olmedo-Pelayo J; Instituto de Biomedicina de Sevilla (IBiS), Hospital Virgen del Rocío-CSIC-Universidad de Sevilla, 41013 Seville, Spain.; Departamento de Genética, Universidad de Sevilla, 41080 Seville, Spain.

Subjects: Translocation, Genetic*; DNA End-Joining Repair/DNA End-Joining Repair/DNA End-Joining Repair/*genetics ; DNA Topoisomerases, Type II/DNA Topoisomerases, Type II/DNA Topoisomerases, Type II/*genetics

  • Source: Nucleic acids research [Nucleic Acids Res] 2020 Sep 18; Vol. 48 (16), pp. 9147-9160.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Kin17 facilitates multiple double-strand break repair pathways that govern B cell class switching.

  • Authors : Le MX; Department of Immunology, University of Toronto, Medical Sciences Building, Toronto, Ontario, M5S1A8, Canada.; Haddad D

Subjects: DNA Breaks, Double-Stranded*; B-Lymphocytes/B-Lymphocytes/B-Lymphocytes/*immunology ; DNA End-Joining Repair/DNA End-Joining Repair/DNA End-Joining Repair/*immunology

  • Source: Scientific reports [Sci Rep] 2016 Nov 17; Vol. 6, pp. 37215. Date of Electronic Publication: 2016 Nov 17.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

V(D)J recombination process and the Pre-B to immature B-cells transition are altered in Fanca -/- mice.

  • Authors : Nguyen TV; CNRS UMR 8200 - Gustave Roussy, Villejuif, France.; Université Paris Saclay, Orsay, France.

Subjects: B-Lymphocytes/B-Lymphocytes/B-Lymphocytes/*immunology ; Fanconi Anemia Complementation Group A Protein/Fanconi Anemia Complementation Group A Protein/Fanconi Anemia Complementation Group A Protein/*immunology ; Precursor Cells, B-Lymphoid/Precursor Cells, B-Lymphoid/Precursor Cells, B-Lymphoid/*immunology

  • Source: Scientific reports [Sci Rep] 2016 Nov 24; Vol. 6, pp. 36906. Date of Electronic Publication: 2016 Nov 24.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Requirement for Parp-1 and DNA ligases 1 or 3 but not of Xrcc1 in chromosomal translocation formation by backup end joining.

  • Authors : Soni A; Institute of Medical Radiation Biology, University of Duisburg-Essen Medical School, 45122 Essen, Germany.; Siemann M

Subjects: DNA End-Joining Repair* ; Translocation, Genetic*; DNA Ligases/DNA Ligases/DNA Ligases/*physiology

  • Source: Nucleic acids research [Nucleic Acids Res] 2014 Jun; Vol. 42 (10), pp. 6380-92. Date of Electronic Publication: 2014 Apr 19.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Histone deacetylase inhibitors selectively target homology dependent DNA repair defective cells and elevate non-homologous endjoining activity.

  • Authors : Smith S; Genome Instability Section, Genetics and Molecular Biology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America.; Fox J

Subjects: B-Lymphocytes/B-Lymphocytes/B-Lymphocytes/*metabolism ; DNA End-Joining Repair/DNA End-Joining Repair/DNA End-Joining Repair/*genetics ; DNA Repair/DNA Repair/DNA Repair/*genetics

  • Source: PloS one [PLoS One] 2014 Jan 23; Vol. 9 (1), pp. e87203. Date of Electronic Publication: 2014 Jan 23 (Print Publication: 2014).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Combined deletion of Xrcc4 and Trp53 in mouse germinal center B cells leads to novel B cell lymphomas with clonal heterogeneity.

  • Authors : Chen Z; Department of Immunology and Microbiology, University of Colorado, Anschutz Medical Campus, 12800 E. 19th Ave, Mail Stop 8333, Aurora, CO, 80045, USA.; Department of Biomedical Research, National Jewish Health, Denver, CO, 80206, USA.

Subjects: B-Lymphocytes/B-Lymphocytes/B-Lymphocytes/*metabolism ; DNA-Binding Proteins/DNA-Binding Proteins/DNA-Binding Proteins/*genetics ; Lymphoma, B-Cell/Lymphoma, B-Cell/Lymphoma, B-Cell/*genetics

  • Source: Journal of hematology & oncology [J Hematol Oncol] 2016 Jan 07; Vol. 9, pp. 2. Date of Electronic Publication: 2016 Jan 07.Publisher: Biomed Central Country of Publication: England NLM ID: 101468937 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-8722

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  • 1-10 of  32 نتائج ل ""joining""