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Academic Journal

Recommended testing algorithms for NTRK gene fusions in pediatric and selected adult cancers: Consensus of a Singapore Task Force.

  • Authors : Lim KHT; Division of Pathology, Department of Anatomical Pathology, Singapore General Hospital, Singapore.; Kong HL

Subjects: Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/therapeutic use ; Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/drug therapy ; Lung Neoplasms*/Lung Neoplasms*/Lung Neoplasms*/drug therapy

  • Source: Asia-Pacific journal of clinical oncology [Asia Pac J Clin Oncol] 2022 Aug; Vol. 18 (4), pp. 394-403. Date of Electronic Publication: 2021 Nov 21.Publisher: Blackwell Pub. Asia Country of Publication: Australia NLM ID: 101241430 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Biomarker LEPRE1 induces pelitinib-specific drug responsiveness by regulating ABCG2 expression and tumor transition states in human leukemia and lung cancer.

  • Authors : Lee AR; Department of Advanced Toxicology, Korea Institute of Toxicology (KIT), Daejeon, 34114, Republic of Korea.; Bio Center, LegoChem Biosciences, Inc., Daejeon, 34002, Republic of Korea.

Subjects: Biomarkers, Tumor*; ATP Binding Cassette Transporter, Subfamily G, Member 2/ATP Binding Cassette Transporter, Subfamily G, Member 2/ATP Binding Cassette Transporter, Subfamily G, Member 2/*genetics ; ATP Binding Cassette Transporter, Subfamily G, Member 2/ATP Binding Cassette Transporter, Subfamily G, Member 2/ATP Binding Cassette Transporter, Subfamily G, Member 2/*metabolism

  • Source: Scientific reports [Sci Rep] 2022 Feb 21; Vol. 12 (1), pp. 2928. Date of Electronic Publication: 2022 Feb 21.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Fucoidan suppresses the gastric cancer cell malignant phenotype and production of TGF-β1 via CLEC-2.

  • Authors : Xu L; NHC Key Laboratory of Glycoconjugate Research, Fudan University, 138 Yixueyuan Road, Shanghai 200032, China.; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, 138 Yixueyuan Road, Shanghai 200032, China.

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Lectins, C-Type/Lectins, C-Type/Lectins, C-Type/*antagonists & inhibitors ; Membrane Glycoproteins/Membrane Glycoproteins/Membrane Glycoproteins/*antagonists & inhibitors

  • Source: Glycobiology [Glycobiology] 2020 Apr 20; Vol. 30 (5), pp. 301-311.Publisher: IRL Press at Oxford University Press Country of Publication: England NLM ID: 9104124 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Eugenol-Induced Autophagy and Apoptosis in Breast Cancer Cells via PI3K/AKT/FOXO3a Pathway Inhibition.

  • Authors : Abdullah ML; Experimental Medicine Department, King Abdullah International Medical Research Center, King Saud bin Abdulaziz University for Health Sciences, MNGHA, Riyadh 11426, Saudi Arabia.; Pharmacology and Toxicology Department, King Saud University, Riyadh 11426, Saudi Arabia.

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Apoptosis/Apoptosis/Apoptosis/*drug effects ; Autophagy/Autophagy/Autophagy/*drug effects

  • Source: International journal of molecular sciences [Int J Mol Sci] 2021 Aug 26; Vol. 22 (17). Date of Electronic Publication: 2021 Aug 26.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Assessing Molecular Docking Tools to Guide Targeted Drug Discovery of CD38 Inhibitors.

  • Authors : Boittier ED; Cancer & Ageing Research Program, Institute of Health and Biomedical Innovation at the Translational Research Institute (TRI), Queensland University of Technology (QUT), Brisbane, Queensland 4102, Australia.; Tang YY

Subjects: ADP-ribosyl Cyclase 1/ADP-ribosyl Cyclase 1/ADP-ribosyl Cyclase 1/*antagonists & inhibitors ; ADP-ribosyl Cyclase 1/ADP-ribosyl Cyclase 1/ADP-ribosyl Cyclase 1/*chemistry ; Drug Discovery/Drug Discovery/Drug Discovery/*methods

  • Source: International journal of molecular sciences [Int J Mol Sci] 2020 Jul 22; Vol. 21 (15). Date of Electronic Publication: 2020 Jul 22.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Molecular and Functional Analysis of Choline Transporters and Antitumor Effects of Choline Transporter-Like Protein 1 Inhibitors in Human Pancreatic Cancer Cells.

  • Authors : Hirai K; Institute of Medical Science, Tokyo Medical University, 6-1-1 Shinjuku, Shinjuku-ku, Tokyo 160-8402, Japan.; Watanabe S

Subjects: Antigens, CD/Antigens, CD/Antigens, CD/*metabolism ; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Hemicholinium 3/Hemicholinium 3/Hemicholinium 3/*pharmacology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2020 Jul 22; Vol. 21 (15). Date of Electronic Publication: 2020 Jul 22.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

The Cytocidal Spectrum of Bacillus thuringiensis Toxins: From Insects to Human Cancer Cells.

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Bacillus thuringiensis Toxins/Bacillus thuringiensis Toxins/Bacillus thuringiensis Toxins/*pharmacology ; Endotoxins/Endotoxins/Endotoxins/*pharmacology

  • Source: Toxins [Toxins (Basel)] 2020 May 06; Vol. 12 (5). Date of Electronic Publication: 2020 May 06.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101530765 Publication Model: Electronic Cited Medium: Internet ISSN: 2072-6651

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Academic Journal

Discovery of a Highly Selective MC1R Agonists Pentapeptide to Be Used as a Skin Pigmentation Enhancer and with Potential Anti-Aging Properties.

  • Authors : Jackson E; DSM Nutritional Products, Personal Care and Aroma, 4303, Kaiseraugst, Switzerland.; Heidl M

Subjects: Drug Discovery* ; Oligopeptides*/Oligopeptides*/Oligopeptides*/chemistry ; Oligopeptides*/Oligopeptides*/Oligopeptides*/pharmacology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2019 Dec 05; Vol. 20 (24). Date of Electronic Publication: 2019 Dec 05.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

An Autophagy Modifier Screen Identifies Small Molecules Capable of Reducing Autophagosome Accumulation in a Model of CLN3-Mediated Neurodegeneration.

  • Authors : Petcherski A; Center for Genomic Medicine, Department of Neurology, Massachusetts General Hospital Research Institute, Harvard Medical School, Boston, MA 02114, USA.; Center for Membrane Proteomics, Goethe University of Frankfurt, 60438 Frankfurt am Main, Germany.

Subjects: Autophagosomes/Autophagosomes/Autophagosomes/*drug effects ; Drug Discovery/Drug Discovery/Drug Discovery/*methods ; Fluspirilene/Fluspirilene/Fluspirilene/*pharmacology

  • Source: Cells [Cells] 2019 Nov 27; Vol. 8 (12). Date of Electronic Publication: 2019 Nov 27.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

Trypanosoma brucei Interaction with Host: Mechanism of VSG Release as Target for Drug Discovery for African Trypanosomiasis.

  • Authors : Moreno CJG; Programa de Pós-graduação em Bioquímica, Centro de Biociências, Universidade Federal do Rio Grande do Norte, Natal 59064-741, Brazil. .; Temporão A

Subjects: Drug Discovery* ; Host-Parasite Interactions*; Membrane Glycoproteins/Membrane Glycoproteins/Membrane Glycoproteins/*metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2019 Mar 25; Vol. 20 (6). Date of Electronic Publication: 2019 Mar 25.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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