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Academic Journal

Multicomponent Reaction-Assisted Drug Discovery: A Time- and Cost-Effective Green Approach Speeding Up Identification and Optimization of Anticancer Drugs.

  • Authors : Graziano G; Department of Pharmacy-Pharmaceutical Sciences, University of Bari 'Aldo Moro', 70125 Bari, Italy.; Center for Research in Biological Chemistry and Molecular Materials (CiQUS), Department of Organic Chemistry, University of Santiago de Compostela, 15782 Santiago de Compostela, Spain.

Subjects: Drug Discovery* ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/therapeutic use; Cost-Benefit Analysis

  • Source: International journal of molecular sciences [Int J Mol Sci] 2023 Apr 01; Vol. 24 (7). Date of Electronic Publication: 2023 Apr 01.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Atropisomerism transforming anti-cancer drug discovery.

  • Authors : Patel S; SVKM's Dr Bhanuben Nanavati College of Pharmacy, Mumbai, India.; Sandha K

Subjects: Drug Discovery* ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/therapeutic use

  • Source: Chemical biology & drug design [Chem Biol Drug Des] 2023 Jan; Vol. 101 (1), pp. 138-157. Date of Electronic Publication: 2022 Oct 28.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101262549 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

canSAR: update to the cancer translational research and drug discovery knowledgebase.

  • Authors : di Micco P; The Department of Genomic Medicine & The Institute of Data Science in Oncology, MD Anderson Cancer Center, Houston, TX, USA.; The Department of Data Science, The Institute of Cancer Research, London, UK.

Subjects: Drug Discovery* ; Knowledge Bases* ; Translational Research, Biomedical*

  • Source: Nucleic acids research [Nucleic Acids Res] 2023 Jan 06; Vol. 51 (D1), pp. D1212-D1219.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

The discovery of a novel series of potential ERRα inverse agonists based on p-nitrobenzenesulfonamide template for triple-negative breast cancer in vivo .

  • Authors : Gao Z; School of Chemistry and Chemical Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan, P. R. China.; Wang T

Subjects: Drug Discovery*; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Nitrobenzenes/Nitrobenzenes/Nitrobenzenes/*pharmacology

  • Source: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2022 Dec; Vol. 37 (1), pp. 125-134.Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print Cited Medium: Internet ISSN: 1475-6374

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Academic Journal

Discovery of a novel Aurora B inhibitor GSK650394 with potent anticancer and anti- aspergillus fumigatus dual efficacies in vitro .

  • Authors : He Y; College of Chemistry, Fuzhou University, Fuzhou, China.; Fu W

Subjects: Drug Discovery*; Antifungal Agents/Antifungal Agents/Antifungal Agents/*pharmacology ; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology

  • Source: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2022 Dec; Vol. 37 (1), pp. 109-117.Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print Cited Medium: Internet ISSN: 1475-6374

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Academic Journal

Application of Pharmacokinetic Prediction Platforms in the Design of Optimized Anti-Cancer Drugs.

  • Authors : Beck TC; College of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.; Department of Drug Discovery and Biomedical Sciences, Medical University of South Carolina, Charleston, SC 29425, USA.

Subjects: Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/therapeutic use ; Drug Discovery*

  • Source: Molecules (Basel, Switzerland) [Molecules] 2022 Jun 08; Vol. 27 (12). Date of Electronic Publication: 2022 Jun 08.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

Designing strategies of small-molecule compounds for modulating non-coding RNAs in cancer therapy.

  • Authors : Zhao R; State Key Laboratory of Biotherapy and Cancer Center, and Department of Gastrointestinal Surgery, West China Hospital, Sichuan University, Chengdu, 610041, China.; Fu J

Subjects: Drug Discovery*; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Neoplasms/Neoplasms/Neoplasms/*drug therapy

  • Source: Journal of hematology & oncology [J Hematol Oncol] 2022 Feb 05; Vol. 15 (1), pp. 14. Date of Electronic Publication: 2022 Feb 05.Publisher: Biomed Central Country of Publication: England NLM ID: 101468937 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-8722

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Academic Journal

The Discovery of New Drug-Target Interactions for Breast Cancer Treatment.

  • Authors : Song J; Department of Biostatistics, School of Public Health, Peking University, Beijing 100191, China.; Xu Z

Subjects: Drug Discovery*; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*drug therapy

  • Source: Molecules (Basel, Switzerland) [Molecules] 2021 Dec 10; Vol. 26 (24). Date of Electronic Publication: 2021 Dec 10.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

Discovery of the natural product 3',4',7,8-tetrahydroxyflavone as a novel and potent selective BRD4 bromodomain 2 inhibitor.

  • Authors : Li J; School of Medicine & Holistic Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.; Zou W

Subjects: Drug Discovery*; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Biological Products/Biological Products/Biological Products/*pharmacology

  • Source: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2021 Dec; Vol. 36 (1), pp. 903-913.Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print Cited Medium: Internet ISSN: 1475-6374

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Academic Journal

Discovery of new quinolines as potent colchicine binding site inhibitors: design, synthesis, docking studies, and anti-proliferative evaluation.

  • Authors : Hagras M; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt.; El Deeb MA

Subjects: Drug Discovery* ; Molecular Docking Simulation*; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology

  • Source: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2021 Dec; Vol. 36 (1), pp. 640-658.Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print Cited Medium: Internet ISSN: 1475-6374

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