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Academic Journal

Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining.

  • Authors : Maruyama T; Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, USA.; Dougan SK

Subjects: CRISPR-Cas Systems/CRISPR-Cas Systems/CRISPR-Cas Systems/*genetics ; DNA End-Joining Repair/DNA End-Joining Repair/DNA End-Joining Repair/*genetics ; DNA Ligases/DNA Ligases/DNA Ligases/*genetics

  • Source: Nature biotechnology [Nat Biotechnol] 2015 May; Vol. 33 (5), pp. 538-42. Date of Electronic Publication: 2015 Mar 23.Publisher: Nature America Publishing Country of Publication: United States NLM ID: 9604648 Publication Model: Print-Electronic

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Academic Journal

Increasing the size of rAAV-mediated expression cassettes in vivo by intermolecular joining of two complementary vectors.

  • Authors : Nakai H; Program in Human Gene Therapy, Department of Pediatrics and Genetics, Stanford University, Stanford, CA 94305, USA.; Storm TA

Subjects: Recombination, Genetic*; Dependovirus/Dependovirus/Dependovirus/*genetics ; Genetic Vectors/Genetic Vectors/Genetic Vectors/*administration & dosage

  • Source: Nature biotechnology [Nat Biotechnol] 2000 May; Vol. 18 (5), pp. 527-32.Publisher: Nature America Publishing Country of Publication: United States NLM ID: 9604648 Publication Model: Print Cited

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Academic Journal

Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells.

  • Authors : Chu VT; Max-Delbrück-Center for Molecular Medicine, Berlin, Germany.; Weber T

Subjects: CRISPR-Cas Systems/CRISPR-Cas Systems/CRISPR-Cas Systems/*genetics ; DNA End-Joining Repair/DNA End-Joining Repair/DNA End-Joining Repair/*genetics ; Genetic Engineering/Genetic Engineering/Genetic Engineering/*methods

  • Source: Nature biotechnology [Nat Biotechnol] 2015 May; Vol. 33 (5), pp. 543-8. Date of Electronic Publication: 2015 Mar 24.Publisher: Nature America Publishing Country of Publication: United States NLM ID: 9604648 Publication Model: Print-Electronic

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Academic Journal

Photoactivatable CRISPR-Cas9 for optogenetic genome editing.

  • Authors : Nihongaki Y; Graduate School of Arts and Sciences, The University of Tokyo, Komaba, Meguro-ku, Tokyo, Japan.; Kawano F

Subjects: CRISPR-Cas Systems/CRISPR-Cas Systems/CRISPR-Cas Systems/*genetics ; CRISPR-Cas Systems/CRISPR-Cas Systems/CRISPR-Cas Systems/*radiation effects ; Genetic Engineering/Genetic Engineering/Genetic Engineering/*methods

  • Source: Nature biotechnology [Nat Biotechnol] 2015 Jul; Vol. 33 (7), pp. 755-60. Date of Electronic Publication: 2015 Jun 15.Publisher: Nature America Publishing Country of Publication: United States NLM ID: 9604648 Publication Model: Print-Electronic

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Academic Journal

A load driver device for engineering modularity in biological networks.

  • Authors : Mishra D; 1] Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA. [2] Synthetic Biology Center, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.; Rivera PM

Subjects: Gene Regulatory Networks* ; Models, Theoretical*; Binding Sites

  • Source: Nature biotechnology [Nat Biotechnol] 2014 Dec; Vol. 32 (12), pp. 1268-75. Date of Electronic Publication: 2014 Nov 24.Publisher: Nature America Publishing Country of Publication: United States NLM ID: 9604648 Publication Model: Print-Electronic

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Academic Journal

Simultaneous editing of three homoeoalleles in hexaploid bread wheat confers heritable resistance to powdery mildew.

  • Authors : Wang Y; 1] State Key Laboratory of Plant Cell and Chromosome Engineering, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China. [2].; Cheng X

Subjects: Alleles* ; RNA Editing*; Ascomycota/Ascomycota/Ascomycota/*pathogenicity

  • Source: Nature biotechnology [Nat Biotechnol] 2014 Sep; Vol. 32 (9), pp. 947-51. Date of Electronic Publication: 2014 Jul 20.Publisher: Nature America Publishing Country of Publication: United States NLM ID: 9604648 Publication Model: Print-Electronic

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Academic Journal

An unbiased genome-wide analysis of zinc-finger nuclease specificity.

  • Authors : Gabriel R; Department of Translational Oncology, National Center for Tumor Diseases (NCT) and German Cancer Research Center (DKFZ), Heidelberg, Germany.; Lombardo A

Subjects: DNA Breaks, Double-Stranded*; Endodeoxyribonucleases/Endodeoxyribonucleases/Endodeoxyribonucleases/*genetics ; HIV Integrase/HIV Integrase/HIV Integrase/*genetics

  • Source: Nature biotechnology [Nat Biotechnol] 2011 Aug 07; Vol. 29 (9), pp. 816-23. Date of Electronic Publication: 2011 Aug 07.Publisher: Nature America Publishing Country of Publication: United States NLM ID: 9604648 Publication Model: Electronic

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Academic Journal

Targeted integration in rat and mouse embryos with zinc-finger nucleases.

  • Authors : Cui X; Sigma Advanced Genetic Engineering Labs, Sigma-Aldrich Biotechnology, St. Louis, Missouri, USA. ; Ji D

Subjects: Gene Targeting* ; Recombination, Genetic*; Deoxyribonucleases, Type II Site-Specific/Deoxyribonucleases, Type II Site-Specific/Deoxyribonucleases, Type II Site-Specific/*genetics

  • Source: Nature biotechnology [Nat Biotechnol] 2011 Jan; Vol. 29 (1), pp. 64-7. Date of Electronic Publication: 2010 Dec 12.Publisher: Nature America Publishing Country of Publication: United States NLM ID: 9604648 Publication Model: Print-Electronic

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Academic Journal

Autocatalytic aptazymes enable ligand-dependent exponential amplification of RNA.

  • Authors : Lam BJ; Department of Chemistry, The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.; Joyce GF

Subjects: Aptamers, Nucleotide/Aptamers, Nucleotide/Aptamers, Nucleotide/*metabolism ; Polynucleotide Ligases/Polynucleotide Ligases/Polynucleotide Ligases/*metabolism ; RNA/RNA/RNA/*metabolism

  • Source: Nature biotechnology [Nat Biotechnol] 2009 Mar; Vol. 27 (3), pp. 288-92. Date of Electronic Publication: 2009 Feb 22.Publisher: Nature America Publishing Country of Publication: United States NLM ID: 9604648 Publication Model: Print-Electronic

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Academic Journal

Can China's supply of scientific talent keep up with demand?

  • Authors : Wong G; ActoKine Therapeutics, 12 Middlesex Road, #411, Chestnut Hill, Massachusetts 02467, USA.

Subjects: Biotechnology*/Biotechnology*/Biotechnology*/trends ; Drug Industry*/Drug Industry*/Drug Industry*/trends ; Professional Competence*

  • Source: Nature biotechnology [Nat Biotechnol] 2008 Feb; Vol. 26 (2), pp. 243-4.Publisher: Nature America Publishing Country of Publication: United States NLM ID: 9604648 Publication Model: Print Cited

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