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Academic Journal

Evaluation of Possible Proarrhythmic Potency: Comparison of the Effect of Dofetilide, Cisapride, Sotalol, Terfenadine, and Verapamil on hERG and Native IKr Currents and on Cardiac Action Potential.

  • Authors : Orvos P; Department of Pharmacology and Pharmacotherapy, Faculty of Medicine.; Department of Ophthalmology, University of Szeged, Szeged H-6720, Hungary.

Subjects: Action Potentials/Action Potentials/Action Potentials/*drug effects ; Anti-Arrhythmia Agents/Anti-Arrhythmia Agents/Anti-Arrhythmia Agents/*toxicity ; Heart Ventricles/Heart Ventricles/Heart Ventricles/*drug effects

  • Source: Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2019 Apr 01; Vol. 168 (2), pp. 365-380.Publisher: Oxford University Press Country of Publication: United States NLM ID: 9805461 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Relationship between ion currents and membrane capacitance in canine ventricular myocytes.

  • Authors : Horváth B; Department of Physiology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary. .; Faculty of Pharmacy, University of Debrecen, Debrecen, Hungary. .

Subjects: Myocytes, Cardiac*/Myocytes, Cardiac*/Myocytes, Cardiac*/metabolism ; Myocytes, Cardiac*/Myocytes, Cardiac*/Myocytes, Cardiac*/physiology ; Electric Capacitance*

  • Source: Scientific reports [Sci Rep] 2024 May 16; Vol. 14 (1), pp. 11241. Date of Electronic Publication: 2024 May 16.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Na V 1.8 as Proarrhythmic Target in a Ventricular Cardiac Stem Cell Model.

  • Authors : Hartmann N; Clinic for Cardiology and Pneumology, University Medical Center, 37075 Göttingen, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Göttingen and Rhein Main, 61231 Bad Nauheim, Germany.

Subjects: NAV1.8 Voltage-Gated Sodium Channel*/NAV1.8 Voltage-Gated Sodium Channel*/NAV1.8 Voltage-Gated Sodium Channel*/metabolism ; NAV1.8 Voltage-Gated Sodium Channel*/NAV1.8 Voltage-Gated Sodium Channel*/NAV1.8 Voltage-Gated Sodium Channel*/genetics ; Induced Pluripotent Stem Cells*/Induced Pluripotent Stem Cells*/Induced Pluripotent Stem Cells*/metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Jun 02; Vol. 25 (11). Date of Electronic Publication: 2024 Jun 02.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Cellular mechanisms underlying carry-over effects after magnetic stimulation.

  • Authors : Ye H; Department of Biology, Loyola University Chicago, Quinlan Life Sciences Education and Research Center, 1032 W. Sheridan Rd., Chicago, IL, 60660, USA. .; Dima M

Subjects: Neurons*/Neurons*/Neurons*/physiology ; Ion Channels*/Ion Channels*/Ion Channels*/physiology; Membrane Potentials/Membrane Potentials/Membrane Potentials/physiology

  • Source: Scientific reports [Sci Rep] 2024 Mar 02; Vol. 14 (1), pp. 5167. Date of Electronic Publication: 2024 Mar 02.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Ionic Mechanisms of Propagated Repolarization in a One-Dimensional Strand of Human Ventricular Myocyte Model.

  • Authors : Himeno Y; Department of Bioinformatics, College of Life Sciences, Ritsumeikan University, Shiga 525-8577, Japan.; Zhang Y

Subjects: Heart Ventricles* ; Myocytes, Cardiac*/Myocytes, Cardiac*/Myocytes, Cardiac*/physiology; Humans

  • Source: International journal of molecular sciences [Int J Mol Sci] 2023 Oct 19; Vol. 24 (20). Date of Electronic Publication: 2023 Oct 19.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Sex-specific repolarization heterogeneity in mouse left ventricle: Optical mapping combined with mathematical modeling predict the contribution of specific ionic currents.

  • Authors : Moussavi-Torshizi SE; Institute of Neural and Sensory Physiology, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, 40225, Düsseldorf, Germany.; Cardiovascular Research Institute Düsseldorf (CARID), Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, 40225, Düsseldorf, Germany.

Subjects: Heart Ventricles*/Heart Ventricles*/Heart Ventricles*/metabolism ; Electrocardiography*; Female

  • Source: Physiological reports [Physiol Rep] 2023 Jun; Vol. 11 (11), pp. e15670.Publisher: published by Wiley Periodicals, Inc. on behalf of the American Physiological Society and The Physiological Society Country of Publication: United States NLM

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Academic Journal

A computational model of rabbit geometry and ECG: Optimizing ventricular activation sequence and APD distribution.

  • Authors : Moss R; Institute for Experimental Cardiovascular Medicine, University Heart Center Freiburg ⋅ Bad Krozingen, Medical Center-University of Freiburg, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Subjects: Endocardium*/Endocardium*/Endocardium*/physiology ; Heart Ventricles*/Heart Ventricles*/Heart Ventricles*/diagnostic imaging ; Heart Ventricles*/Heart Ventricles*/Heart Ventricles*/metabolism

  • Source: PloS one [PLoS One] 2022 Jun 30; Vol. 17 (6), pp. e0270559. Date of Electronic Publication: 2022 Jun 30 (Print Publication: 2022).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

The development of L-type Ca 2+ current mediated alternans does not depend on the restitution slope in canine ventricular myocardium.

  • Authors : Tóth N; Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Szeged, Dóm tér 12, P.O. Box 427, 6720, Szeged, Hungary.; Szlovák J

Subjects: Action Potentials*; Calcium/Calcium/Calcium/*metabolism ; Heart Ventricles/Heart Ventricles/Heart Ventricles/*physiopathology

  • Source: Scientific reports [Sci Rep] 2021 Aug 17; Vol. 11 (1), pp. 16652. Date of Electronic Publication: 2021 Aug 17.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Pacemaking function of two simplified cell models.

  • Authors : Ryzhii M; Complex Systems Modeling Laboratory, University of Aizu, Aizu-Wakamatsu, Japan.; Ryzhii E

Subjects: Ion Channels* ; Sinoatrial Node*/Sinoatrial Node*/Sinoatrial Node*/physiology; Action Potentials/Action Potentials/Action Potentials/physiology

  • Source: PloS one [PLoS One] 2022 Apr 11; Vol. 17 (4), pp. e0257935. Date of Electronic Publication: 2022 Apr 11 (Print Publication: 2022).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Inferiority complex: why do sensory ion channels multimerize?

  • Authors : Gamper N; School of Biomedical Sciences, Faculty of Biological Sciences, University of Leeds, Leeds, U.K.; Shah S

Subjects: Ion Channels*/Ion Channels*/Ion Channels*/metabolism ; Sensory Receptor Cells*/Sensory Receptor Cells*/Sensory Receptor Cells*/metabolism; Action Potentials

  • Source: Biochemical Society transactions [Biochem Soc Trans] 2022 Feb 28; Vol. 50 (1), pp. 213-222.Publisher: Portland Press On The Behalf Of The Biochemical Society Country of Publication: England NLM ID: 7506897 Publication Model: Print Cited Medium:

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