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Academic Journal

IGF-1R inhibition enhances radiosensitivity and delays double-strand break repair by both non-homologous end-joining and homologous recombination.

  • Authors : Chitnis MM; 1] Department of Oncology Laboratories, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK [2] Department of Oncology, Cancer and Haematology Centre, The Churchill Hospital, Oxford, UK.; Lodhia KA

Subjects: DNA Breaks, Double-Stranded*; DNA End-Joining Repair/DNA End-Joining Repair/DNA End-Joining Repair/*genetics ; Receptor, IGF Type 1/Receptor, IGF Type 1/Receptor, IGF Type 1/*genetics

  • Source: Oncogene [Oncogene] 2014 Nov 06; Vol. 33 (45), pp. 5262-73. Date of Electronic Publication: 2013 Nov 04.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

A novel Ku70 function in colorectal homeostasis separate from nonhomologous end joining.

  • Authors : Puebla-Osorio N; Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Kim J

Subjects: DNA End-Joining Repair* ; Homeostasis*; Adenocarcinoma/Adenocarcinoma/Adenocarcinoma/*genetics

  • Source: Oncogene [Oncogene] 2014 May 22; Vol. 33 (21), pp. 2748-57. Date of Electronic Publication: 2013 Jun 10.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Possible involvement of LKB1-AMPK signaling in non-homologous end joining.

  • Authors : Ui A; 1] Division of Genome Biology, National Cancer Center Research Institute, Tokyo, Japan [2] Division of Dynamic Proteome, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan.; Ogiwara H

Subjects: DNA End-Joining Repair*; AMP-Activated Protein Kinases/AMP-Activated Protein Kinases/AMP-Activated Protein Kinases/*genetics ; AMP-Activated Protein Kinases/AMP-Activated Protein Kinases/AMP-Activated Protein Kinases/*metabolism

  • Source: Oncogene [Oncogene] 2014 Mar 27; Vol. 33 (13), pp. 1640-8. Date of Electronic Publication: 2013 Apr 15.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Rad18 and Rnf8 facilitate homologous recombination by two distinct mechanisms, promoting Rad51 focus formation and suppressing the toxic effect of nonhomologous end joining.

  • Authors : Kobayashi S; Department of Radiation Genetics, Kyoto University Graduate School of Medicine, Kyoto, Japan.; Kasaishi Y

Subjects: DNA End-Joining Repair/DNA End-Joining Repair/DNA End-Joining Repair/*genetics ; DNA-Binding Proteins/DNA-Binding Proteins/DNA-Binding Proteins/*genetics ; Homologous Recombination/Homologous Recombination/Homologous Recombination/*genetics

  • Source: Oncogene [Oncogene] 2015 Aug 13; Vol. 34 (33), pp. 4403-11. Date of Electronic Publication: 2014 Nov 24.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Opposite modifying effects of HR and NHEJ deficiency on cancer risk in Ptc1 heterozygous mouse cerebellum.

  • Authors : Tanori M; Laboratory of Radiation Biology and Biomedicine, Agenzia Nazionale per le Nuove Tecnologie, l'Energia e lo Sviluppo Economico Sostenibile (ENEA) CR-Casaccia, Rome, Italy.; Pasquali E

Subjects: DNA End-Joining Repair* ; Homologous Recombination*; Cerebellar Neoplasms/Cerebellar Neoplasms/Cerebellar Neoplasms/*etiology

  • Source: Oncogene [Oncogene] 2011 Nov 24; Vol. 30 (47), pp. 4740-9. Date of Electronic Publication: 2011 May 23.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Histone acetylation by CBP and p300 at double-strand break sites facilitates SWI/SNF chromatin remodeling and the recruitment of non-homologous end joining factors.

  • Authors : Ogiwara H; Division of Genome Biology, National Cancer Center Research Institute, Chuo-ku, Tokyo, Japan.; Ui A

Subjects: Chromatin Assembly and Disassembly*; Histones/Histones/Histones/*metabolism ; p300-CBP Transcription Factors/p300-CBP Transcription Factors/p300-CBP Transcription Factors/*physiology

  • Source: Oncogene [Oncogene] 2011 May 05; Vol. 30 (18), pp. 2135-46. Date of Electronic Publication: 2011 Jan 10.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Role of SUMO:SIM-mediated protein-protein interaction in non-homologous end joining.

  • Authors : Li YJ; Department of Molecular Medicine, Beckman Research Institute of the City of Hope, Duarte, CA 91010, USA.; Stark JM

Subjects: DNA Repair*/DNA Repair*/DNA Repair*/drug effects; SUMO-1 Protein/SUMO-1 Protein/SUMO-1 Protein/*metabolism; Amino Acid Motifs

  • Source: Oncogene [Oncogene] 2010 Jun 17; Vol. 29 (24), pp. 3509-18. Date of Electronic Publication: 2010 Apr 19.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

S-phase progression stimulates both the mutagenic KU-independent pathway and mutagenic processing of KU-dependent intermediates, for nonhomologous end joining.

  • Authors : Guirouilh-Barbat J; Institut de Radiobiologie Cellulaire et Moléculaire, UMR 217, CNRS, Fontenay-aux-Roses, France.; Huck S

Subjects: Antigens, Nuclear/Antigens, Nuclear/Antigens, Nuclear/*genetics ; DNA Repair/DNA Repair/DNA Repair/*genetics ; DNA-Binding Proteins/DNA-Binding Proteins/DNA-Binding Proteins/*genetics

  • Source: Oncogene [Oncogene] 2008 Mar 13; Vol. 27 (12), pp. 1726-36. Date of Electronic Publication: 2007 Sep 24.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

V(D)J and immunoglobulin class switch recombinations: a paradigm to study the regulation of DNA end-joining.

Subjects: Recombination, Genetic*; Immunoglobulin Class Switching/Immunoglobulin Class Switching/Immunoglobulin Class Switching/*genetics ; VDJ Recombinases/VDJ Recombinases/VDJ Recombinases/*metabolism

  • Source: Oncogene [Oncogene] 2007 Dec 10; Vol. 26 (56), pp. 7780-91.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Non-homologous end-joining, a sticky affair.

  • Authors : van Gent DC; Department of Cell Biology and Genetics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands. ; van der Burg M

Subjects: DNA Damage* ; DNA Repair* ; Recombination, Genetic*

  • Source: Oncogene [Oncogene] 2007 Dec 10; Vol. 26 (56), pp. 7731-40.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print Cited Medium: Internet ISSN:

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