Item request has been placed! ×
Item request cannot be made. ×
loading  Processing Request
Item request has been placed! ×
Item request cannot be made. ×
loading  Processing Request
Academic Journal

Mutations in UBA3 Confer Resistance to the NEDD8-Activating Enzyme Inhibitor MLN4924 in Human Leukemic Cells

Subjects: Biology and Life Sciences; Biochemistry; Medicine and Health Sciences

  • Source: Xu, G. W., J. I. Toth, S. R. da Silva, S. Paiva, J. L. Lukkarila, R. Hurren, N. Maclean, et al. 2014. “Mutations in UBA3 Confer Resistance to the NEDD8-Activating Enzyme Inhibitor MLN4924 in Human

تفاصيل العنوان

×
Academic Journal

Regulation of MYC Expression and Differential JQ1 Sensitivity in Cancer Cells

Subjects: Biology; Biochemistry; Genetics

  • Source: Fowler, Trent, Payel Ghatak, David H. Price, Ronald Conaway, Joan Conaway, Cheng-Ming Chiang, James E. Bradner, Ali Shilatifard, and Ananda L. Roy. 2014. “Regulation of MYC Expression and

تفاصيل العنوان

×
Academic Journal

Identification of a New Epitope in uPAR as a Target for the Cancer Therapeutic Monoclonal Antibody ATN-658, a Structural Homolog of the uPAR Binding Integrin CD11b (αM)

Subjects: Biology; Biochemistry; Proteins

  • Source: Xu, X., Y. Cai, Y. Wei, F. Donate, J. Juarez, G. Parry, L. Chen, et al. 2014. “Identification of a New Epitope in uPAR as a Target for the Cancer Therapeutic Monoclonal Antibody ATN-658, a

تفاصيل العنوان

×
Academic Journal

Shifts in the Distribution of Mass Densities Is a Signature of Caloric Restriction in Caenorhabditis elegans

Subjects: Biology; Biochemistry; Drug Discovery

  • Source: Reina, Alfonso, Anand Bala Subramaniam, Anna Laromaine, Aravinthan D. T. Samuel, and George M. Whitesides. 2013. “Shifts in the Distribution of Mass Densities Is a Signature of Caloric Restriction

تفاصيل العنوان

×
Academic Journal

Genotype Directed Therapy in Murine Mismatch Repair Deficient Tumors

Subjects: Biology; Biochemistry; Drug Discovery

  • Source: Kucherlapati, Melanie H., Shadi Esfahani, Peiman Habibollahi, Junning Wang, Eric R. Still, Roderick T. Bronson, Umar Mahmood, and Raju S. Kucherlapati. 2013. “Genotype Directed Therapy in Murine

تفاصيل العنوان

×
Academic Journal

A Selective HDAC 1/2 Inhibitor Modulates Chromatin and Gene Expression in Brain and Alters Mouse Behavior in Two Mood-Related Tests

Subjects: Biology; Biochemistry; Drug Discovery

  • Source: Schroeder, F. A., M. C. Lewis, D. M. Fass, F. F. Wagner, Y. Zhang, K. M. Hennig, J. Gale, et al. 2013. “A Selective HDAC 1/2 Inhibitor Modulates Chromatin and Gene Expression in Brain and Alters

تفاصيل العنوان

×
Academic Journal

Differential Disruption of EWS-FLI1 Binding by DNA-Binding Agents

Subjects: Biology; Biochemistry; Proteins

  • Source: Chen, Changmin, Diane R. Wonsey, Madeleine E. Lemieux, and Andrew L. Kung. 2013. “Differential Disruption of EWS-FLI1 Binding by DNA-Binding Agents.” PLoS ONE 8 (7): e69714.

تفاصيل العنوان

×
Academic Journal

A New Class of Small Molecule Inhibitor of BMP Signaling

Subjects: Biology; Biochemistry; Chemical Biology

  • Source: Sanvitale, Caroline E., Georgina Kerr, Apirat Chaikuad, Marie-Christine Ramel, Agustin H. Mohedas, Sabine Reichert, You Wang, et al. 2013. A new class of small molecule inhibitor of bmp signaling.

تفاصيل العنوان

×
Academic Journal

Machine Learning Prediction of Cancer Cell Sensitivity to Drugs Based on Genomic and Chemical Properties

Subjects: Biology; Biochemistry; Drug Discovery

  • Source: Menden, Michael P., Francesco Iorio, Mathew Garnett, Ultan McDermott, Cyril H. Benes, Pedro J. Ballester, and Julio Saez-Rodriguez. 2013. Machine learning prediction of cancer cell sensitivity to

تفاصيل العنوان

×
Academic Journal

Identification of Anziaic Acid, a Lichen Depside from Hypotrachyna sp., as a New Topoisomerase Poison Inhibitor

Subjects: Biology; Biochemistry; Enzymes

  • Source: Cheng, Bokun, Shugeng Cao, Victor Vasquez, Thirunavukkarasu Annamalai, Giselle Tamayo-Castillo, Jon Clardy, and Yuk-Ching Tse-Dinh. 2013. Identification of anziaic acid, a lichen depside from

تفاصيل العنوان

×
  • 1-10 of  28 نتائج ل ""Drug discovery""